Detalhe da pesquisa
1.
The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development.
Int J Toxicol
; 41(6): 431-441, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36112859
2.
Nonclinical evaluation of abuse liability of the dual orexin receptor antagonist lemborexant.
Regul Toxicol Pharmacol
; 127: 105053, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34619288
3.
Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation.
Regul Toxicol Pharmacol
; 113: 104624, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32126256
4.
Lack of value of juvenile animal toxicity studies for supporting the safety of pediatric oncology phase I trials.
Regul Toxicol Pharmacol
; 96: 167-177, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29763632
5.
Regulatory Forum commentary: alternative mouse models for future cancer risk assessment.
Toxicol Pathol
; 42(5): 799-806, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23965809
6.
Pharmacokinetics, metabolism and excretion of 14C-monoethyl phthalate (MEP) and 14C-diethyl phthalate (DEP) after single oral and IV administration in the juvenile dog.
Xenobiotica
; 42(4): 389-97, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22054055
7.
Evaluation of Therapeutics for Severely Debilitating or Life-Threatening Diseases or Conditions: Defining Scope to Enable Global Guidance Development.
Clin Pharmacol Ther
; 107(3): 514-520, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31608984