Detalhe da pesquisa
1.
Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex.
Proc Natl Acad Sci U S A
; 118(48)2021 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34819376
2.
Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts.
J Struct Biol
; 208(2): 182-190, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31476368
3.
Evolutionary dynamics of tipifarnib in HRAS mutated head and neck squamous cell carcinoma.
Oral Oncol
; 149: 106688, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38219706
4.
High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun
; 14(1): 4851, 2023 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37563123
5.
B-Cell Infiltrate in the Tumor Microenvironment Is Associated With Improved Survival in Resected Lung Adenocarcinoma.
JTO Clin Res Rep
; 4(7): 100527, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37521368
6.
Deciphering the origin and therapeutic targets of cancer of unknown primary: a case report that illustrates the power of integrative whole-exome and transcriptome sequencing analysis.
Front Oncol
; 13: 1274163, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38318324
7.
Increasing Inhibition of the Rat Brain 2-Oxoglutarate Dehydrogenase Decreases Glutathione Redox State, Elevating Anxiety and Perturbing Stress Adaptation.
Pharmaceuticals (Basel)
; 15(2)2022 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35215295
8.
Delayed Impact of 2-Oxoadipate Dehydrogenase Inhibition on the Rat Brain Metabolism Is Linked to Protein Glutarylation.
Front Med (Lausanne)
; 9: 896263, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35721081
9.
Administration of Phosphonate Inhibitors of Dehydrogenases of 2-Oxoglutarate and 2-Oxoadipate to Rats Elicits Target-Specific Metabolic and Physiological Responses.
Front Chem
; 10: 892284, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35795216
10.
Case report: Metastatic urothelial cancer with an exceptional response to immunotherapy and comprehensive understanding of the tumor and the tumor microenvironment.
Front Oncol
; 12: 1006017, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36387205
11.
Severe Spinal Cord Injury in Rats Induces Chronic Changes in the Spinal Cord and Cerebral Cortex Metabolism, Adjusted by Thiamine That Improves Locomotor Performance.
Front Mol Neurosci
; 14: 620593, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33867932
12.
Physiological and Biochemical Markers of the Sex-Specific Sensitivity to Epileptogenic Factors, Delayed Consequences of Seizures and Their Response to Vitamins B1 and B6 in a Rat Model.
Pharmaceuticals (Basel)
; 14(8)2021 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34451834
13.
A novel variant m.641A>T in the mitochondrial MT-TF gene is associated with epileptic encephalopathy in adolescent.
Mitochondrion
; 47: 10-17, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31009750
14.
Delayed Influence of Spinal Cord Injury on the Amino Acids of NO⢠Metabolism in Rat Cerebral Cortex Is Attenuated by Thiamine.
Front Med (Lausanne)
; 4: 249, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29379782