Detalhe da pesquisa
1.
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription.
Nucleic Acids Res
; 50(5): 2566-2586, 2022 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35150567
2.
Different class IIa HDACs repressive complexes regulate specific epigenetic responses related to cell survival in leiomyosarcoma cells.
Nucleic Acids Res
; 48(2): 646-664, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31754707
3.
The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness.
PLoS Genet
; 13(4): e1006752, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28419090
4.
Genetic Programs Driving Oncogenic Transformation: Lessons from in Vitro Models.
Int J Mol Sci
; 20(24)2019 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31842516
5.
The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro.
J Cell Sci
; 128(21): 3961-76, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26403201
6.
Selective class IIa HDAC inhibitors: myth or reality.
Cell Mol Life Sci
; 72(1): 73-86, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25189628
7.
A receptor-interacting protein 1 (RIP1)-independent necrotic death under the control of protein phosphatase PP2A that involves the reorganization of actin cytoskeleton and the action of cofilin-1.
J Biol Chem
; 289(37): 25699-710, 2014 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25096578
8.
Class IIa HDACs repressive activities on MEF2-depedent transcription are associated with poor prognosis of ER⺠breast tumors.
FASEB J
; 27(3): 942-54, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23159930
9.
Transcription of endogenous retroviruses in senescent cells contributes to the accumulation of double-stranded RNAs that trigger an anti-viral response that reinforces senescence.
Cell Death Dis
; 15(2): 157, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383514
10.
Changes in chromatin accessibility and transcriptional landscape induced by HDAC inhibitors in TP53 mutated patient-derived colon cancer organoids.
Biomed Pharmacother
; 173: 116374, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38447451
11.
Folding of Class IIa HDAC Derived Peptides into α-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
J Mol Biol
; 436(9): 168541, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38492719
12.
In Vitro and In Vivo Evaluation of the Effects of Drug 2c and Derivatives on Ovarian Cancer Cells.
Pharmaceutics
; 16(5)2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38794326
13.
Acetylation and Phosphorylation in the Regulation of Hypoxia-Inducible Factor Activities: Additional Options to Modulate Adaptations to Changes in Oxygen Levels.
Life (Basel)
; 14(1)2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38276269
14.
HDAC4 in cancer: A multitasking platform to drive not only epigenetic modifications.
Front Mol Biosci
; 10: 1116660, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36762207
15.
Super-enhancer landscape rewiring in cancer: The epigenetic control at distal sites.
Int Rev Cell Mol Biol
; 380: 97-148, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37657861
16.
HDACs and the epigenetic plasticity of cancer cells: Target the complexity.
Pharmacol Ther
; 238: 108190, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35430294
17.
Novel synthesis of 1,2-diaza-1,3-dienes with potential biological activity from cinnamic acids and diazonium salts of anilines.
RSC Adv
; 13(1): 456-463, 2022 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36605622
18.
Proteotoxic stress-induced apoptosis in cancer cells: understanding the susceptibility and enhancing the potency.
Cell Death Discov
; 8(1): 407, 2022 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36195608
19.
Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy.
J Cachexia Sarcopenia Muscle
; 13(2): 1339-1359, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35170869
20.
Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis.
J Cell Mol Med
; 15(9): 1833-46, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21435179