Detalhe da pesquisa
1.
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.
Proc Natl Acad Sci U S A
; 109(15): 5687-92, 2012 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22451937
2.
Analysis of AcrB and AcrB/DARPin ligand complexes by LILBID MS.
Biochim Biophys Acta
; 1808(9): 2189-96, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21616055
3.
Structural and functional aspects of the multidrug efflux pump AcrB.
Biol Chem
; 390(8): 693-9, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19453279
4.
Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB.
Elife
; 32014 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25248080
5.
The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance.
Curr Drug Targets
; 9(9): 729-49, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18781920
6.
Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB.
Nat Struct Mol Biol
; 15(2): 199-205, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18223659