Detalhe da pesquisa
1.
Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria.
Proc Natl Acad Sci U S A
; 121(15): e2317274121, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38579010
2.
Western boundary currents regulated by interaction between ocean eddies and the atmosphere.
Nature
; 535(7613): 533-7, 2016 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466126
3.
Computational studies of molecular pre-organization through macrocyclization: Conformational distribution analysis of closely related non-macrocyclic and macrocyclic analogs.
Bioorg Med Chem
; 49: 116399, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34601455
4.
Design of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization.
Chemistry
; 26(31): 7131-7139, 2020 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32255539
5.
Conformational analysis of macrocycles: comparing general and specialized methods.
J Comput Aided Mol Des
; 34(3): 231-252, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31965404
6.
Docking of Macrocycles: Comparing Rigid and Flexible Docking in Glide.
J Chem Inf Model
; 57(2): 190-202, 2017 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28079375
7.
Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB).
Bioorg Med Chem
; 25(3): 897-911, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28038943
8.
Interannual atmospheric variability forced by the deep equatorial Atlantic Ocean.
Nature
; 473(7348): 497-500, 2011 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21593764
9.
Synthesis of 11C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation.
Molecules
; 22(10)2017 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28994734
10.
Discovery of pyrazinone based compounds that potently inhibit the drug-resistant enzyme variant R155K of the hepatitis C virus NS3 protease.
Bioorg Med Chem
; 24(12): 2603-20, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27160057
11.
Toward a benchmarking data set able to evaluate ligand- and structure-based virtual screening using public HTS data.
J Chem Inf Model
; 55(2): 343-53, 2015 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25564966
12.
Coastal trapped waves and tidal mixing control primary production in the tropical Angolan upwelling system.
Sci Adv
; 10(4): eadj6686, 2024 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38277464
13.
Enhanced reporting of deaths among Aboriginal and Torres Strait Islander peoples using linked administrative health datasets.
BMC Med Res Methodol
; 12: 91, 2012 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22747900
14.
Diastereoselective Synthesis of N-Methylspiroindolines by Intramolecular Mizoroki-Heck Annulations.
ACS Omega
; 7(36): 32525-32535, 2022 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36120037
15.
Synthesis and In Vitro Biological Evaluation of Quinolinyl Pyrimidines Targeting Type II NADH-Dehydrogenase (NDH-2).
ACS Infect Dis
; 8(3): 482-498, 2022 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35184552
16.
Imitation of ß-lactam binding enables broad-spectrum metallo-ß-lactamase inhibitors.
Nat Chem
; 14(1): 15-24, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34903857
17.
Surface cooling caused by rare but intense near-inertial wave induced mixing in the tropical Atlantic.
Nat Commun
; 11(1): 3829, 2020 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737290
18.
Small kinase assay panels can provide a measure of selectivity.
Bioorg Med Chem Lett
; 19(20): 5861-3, 2009 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19748779
19.
Pan-NS3 protease inhibitors of hepatitis C virus based on an R3-elongated pyrazinone scaffold.
Eur J Med Chem
; 148: 453-464, 2018 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29477077
20.
Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase.
Eur J Med Chem
; 157: 1346-1360, 2018 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30196059