Detalhe da pesquisa
1.
USP7 small-molecule inhibitors interfere with ubiquitin binding.
Nature
; 550(7677): 534-538, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045385
2.
Preclinical and Clinical Resistance Profile of EDP-239, a Novel Hepatitis C Virus NS5A Inhibitor.
Antimicrob Agents Chemother
; 60(10): 6216-26, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27503644
3.
Preclinical Profile and Clinical Efficacy of a Novel Hepatitis C Virus NS5A Inhibitor, EDP-239.
Antimicrob Agents Chemother
; 60(10): 6207-15, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27503640
4.
Proteomics of broad deubiquitylase inhibition unmasks redundant enzyme function to reveal substrates and assess enzyme specificity.
Cell Chem Biol
; 28(4): 487-502.e5, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33417828
5.
Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases.
J Mol Biol
; 431(6): 1160-1171, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30763569
6.
Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.
Structure
; 27(4): 590-605.e5, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30713027
7.
K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair.
Sci Signal
; 11(533)2018 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29871913
8.
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.
Nat Commun
; 9(1): 1162, 2018 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29563501
9.
Targeting of proteins to membranes through hedgehog auto-processing.
Nat Biotechnol
; 21(8): 936-40, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12858181
10.
DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells.
Cell Rep
; 5(3): 826-38, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24210823
11.
Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop.
Proc Natl Acad Sci U S A
; 99(16): 10700-5, 2002 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-12149456