Detalhe da pesquisa
1.
The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe?
Annu Rev Physiol
; 83: 127-151, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33228454
2.
Clinical validation of circulating GDF15/MIC-1 as a marker of response to docetaxel and survival in men with metastatic castration-resistant prostate cancer.
Prostate
; 84(8): 747-755, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38544345
3.
GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS.
Int J Obes (Lond)
; 43(12): 2370-2380, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31152154
4.
Interaction of Human Chloride Intracellular Channel Protein 1 (CLIC1) with Lipid Bilayers: A Fluorescence Study.
Biochemistry
; 55(27): 3825-33, 2016 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27299171
5.
CLIC proteins, ezrin, radixin, moesin and the coupling of membranes to the actin cytoskeleton: a smoking gun?
Biochim Biophys Acta
; 1838(2): 643-57, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23732235
6.
Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification.
J Cell Sci
; 125(Pt 22): 5479-88, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22956539
7.
Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.
Nat Med
; 13(11): 1333-40, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17982462
8.
GDF15 analogs as obesity therapeutics.
Cell Metab
; 35(2): 227-228, 2023 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36754014
9.
GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway.
Cell Metab
; 35(8): 1341-1355.e3, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37433299
10.
ß-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFß receptor signaling.
iScience
; 26(4): 106477, 2023 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37091234
11.
CCAAT/enhancer binding protein-δ expression by dendritic cells regulates CNS autoimmune inflammatory disease.
J Neurosci
; 31(48): 17612-21, 2011 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22131422
12.
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease.
Nephrol Dial Transplant
; 27(1): 70-5, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21940482
13.
Dendritic cells and multiple sclerosis: disease, tolerance and therapy.
Int J Mol Sci
; 14(1): 547-62, 2012 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23271370
14.
Transmembrane extension and oligomerization of the CLIC1 chloride intracellular channel protein upon membrane interaction.
Biochemistry
; 50(50): 10887-97, 2011 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22082111
15.
The TGF-ß superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism.
Growth Factors
; 29(5): 187-95, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21831009
16.
High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40).
J Immunol
; 183(4): 2827-36, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19635903
17.
Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis.
Sci Rep
; 11(1): 5244, 2021 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33664396
18.
Generation and characterization of mice with null mutation of the chloride intracellular channel 1 gene.
Genesis
; 48(2): 127-36, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20049953
19.
Metamorphic response of the CLIC1 chloride intracellular ion channel protein upon membrane interaction.
Biochemistry
; 49(25): 5278-89, 2010 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20507120
20.
Growth differentiation factor-15 slows the growth of murine prostate cancer by stimulating tumor immunity.
PLoS One
; 15(6): e0233846, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32502202