Detalhe da pesquisa
1.
Studies on enmetazobactam clarify mechanisms of widely used ß-lactamase inhibitors.
Proc Natl Acad Sci U S A
; 119(18): e2117310119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35486701
2.
Structural Investigations of the Inhibition of Escherichia coli AmpC ß-Lactamase by Diazabicyclooctanes.
Antimicrob Agents Chemother
; 65(2)2021 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199391
3.
The Chemical Biology of Human Metallo-ß-Lactamase Fold Proteins.
Trends Biochem Sci
; 41(4): 338-355, 2016 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26805042
4.
A Fluorescence-Based Assay for Screening ß-Lactams Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2.
Chembiochem
; 21(3): 368-372, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31322798
5.
Molecular Basis of Class A ß-Lactamase Inhibition by Relebactam.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31383664
6.
19 Fâ NMR Monitoring of Reversible Protein Post-Translational Modifications: Classâ D ß-Lactamase Carbamylation and Inhibition.
Chemistry
; 25(51): 11837-11841, 2019 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31310409
7.
Profiling interactions of vaborbactam with metallo-ß-lactamases.
Bioorg Med Chem Lett
; 29(15): 1981-1984, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31171422
8.
Non-Hydrolytic ß-Lactam Antibiotic Fragmentation by l,d-Transpeptidases and Serine ß-Lactamase Cysteine Variants.
Angew Chem Int Ed Engl
; 58(7): 1990-1994, 2019 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30569575
9.
Structural/mechanistic insights into the efficacy of nonclassical ß-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates.
Mol Microbiol
; 106(3): 492-504, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28876489
10.
Cyclobutanone Mimics of Intermediates in Metallo-ß-Lactamase Catalysis.
Chemistry
; 24(22): 5734-5737, 2018 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29250863
11.
Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-ß-lactamases.
Bioorg Med Chem
; 26(11): 2928-2936, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29655609
12.
A New Mechanism for ß-Lactamases: Class D Enzymes Degrade 1ß-Methyl Carbapenems through Lactone Formation.
Angew Chem Int Ed Engl
; 57(5): 1282-1285, 2018 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29236332
13.
Crystal structure of human persulfide dioxygenase: structural basis of ethylmalonic encephalopathy.
Hum Mol Genet
; 24(9): 2458-69, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25596185
14.
Cyclic Boronates Inhibit All Classes of ß-Lactamases.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28115348
15.
13C-Carbamylation as a mechanistic probe for the inhibition of class D ß-lactamases by avibactam and halide ions.
Org Biomol Chem
; 15(28): 6024-6032, 2017 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28678295
16.
19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-ß-Lactamase.
Angew Chem Int Ed Engl
; 56(14): 3862-3866, 2017 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28252254
17.
Structural and Biochemical Characterization of Rm3, a Subclass B3 Metallo-ß-Lactamase Identified from a Functional Metagenomic Study.
Antimicrob Agents Chemother
; 60(10): 5828-40, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27431213
18.
Interaction of Avibactam with Class B Metallo-ß-Lactamases.
Antimicrob Agents Chemother
; 60(10): 5655-62, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27401561
19.
Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates.
Antimicrob Agents Chemother
; 60(7): 4170-5, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27139464
20.
Structural Basis of Metallo-ß-Lactamase Inhibition by Captopril Stereoisomers.
Antimicrob Agents Chemother
; 60(1): 142-50, 2016 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26482303