Detalhe da pesquisa
1.
Engineering Cancer Antigen-Specific T Cells to Overcome the Immunosuppressive Effects of TGF-ß.
J Immunol
; 208(1): 169-180, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853077
2.
Anti-IL-7 receptor α monoclonal antibody (GSK2618960) in healthy subjects - a randomized, double-blind, placebo-controlled study.
Br J Clin Pharmacol
; 85(2): 304-315, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30161291
3.
CCL20 neutralization by a monoclonal antibody in healthy subjects selectively inhibits recruitment of CCR6+ cells in an experimental suction blister.
Br J Clin Pharmacol
; 83(9): 1976-1990, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28295451
4.
Characterisation of the clinical and activated T cell response to repeat delayed-type hypersensitivity skin challenges in human subjects, with KLH and PPD, as a potential model to test T cell-targeted therapies.
Inflamm Res
; 65(5): 389-404, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26969026
5.
Immuno-PET Monitoring of CD8+ T Cell Infiltration Post ICOS Agonist Antibody Treatment Alone and in Combination with PD-1 Blocking Antibody Using a 89Zr Anti-CD8+ Mouse Minibody in EMT6 Syngeneic Tumor Mouse.
Mol Imaging Biol
; 25(3): 528-540, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36266600
6.
Activating Inducible T-cell Costimulator Yields Antitumor Activity Alone and in Combination with Anti-PD-1 Checkpoint Blockade.
Cancer Res Commun
; 3(8): 1564-1579, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37593752
7.
Induction of homologous rather than heterologous antigen-specific CD4 T cell responses is critical for functional CD8 T cell responses in mice transgenic for a foreign antigen.
J Immunol
; 185(8): 4590-601, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20861346
8.
Characterization of the robust humoral immune response to GSK2618960, a humanized anti-IL-7 receptor monoclonal antibody, observed in healthy subjects in a Phase 1 study.
PLoS One
; 16(3): e0249049, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33755713
9.
Depletion of LAG-3+ T Cells Translated to Pharmacology and Improvement in Psoriasis Disease Activity: A Phase I Randomized Study of mAb GSK2831781.
Clin Pharmacol Ther
; 109(5): 1293-1303, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33113155
10.
Programmed death 1 expression during antiviral treatment of chronic hepatitis B: Impact of hepatitis B e-antigen seroconversion.
Hepatology
; 48(3): 759-69, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18697210
11.
High OX-40 expression in the tumor immune infiltrate is a favorable prognostic factor of overall survival in non-small cell lung cancer.
J Immunother Cancer
; 7(1): 351, 2019 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31843013
12.
Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments.
PLoS One
; 13(11): e0206223, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30388137
13.
Safety, tolerability, pharmacokinetics and pharmacodynamics of an anti- oncostatin M monoclonal antibody in rheumatoid arthritis: results from phase II randomized, placebo-controlled trials.
Arthritis Res Ther
; 15(5): R132, 2013 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24286335
14.
Development of an Escherichia coli expressing listeriolysin-O vaccine against Wilms tumor gene 1-expressing tumors.
J Immunother
; 32(8): 845-55, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19752749
15.
Perturbation of naive TCR transgenic T cell functional responses and upstream activation events by anti-CD4 monoclonal antibodies.
Eur J Immunol
; 32(2): 333-40, 2002 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-11807772
16.
Infection of mouse bone marrow-derived dendritic cells with recombinant adenovirus vectors leads to presentation of encoded antigen by both MHC class I and class II molecules-potential benefits in vaccine design.
Vaccine
; 21(3-4): 231-42, 2002 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-12450698
17.
Imiquimod and resiquimod in a mouse model: adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery.
Vaccine
; 22(13-14): 1799-809, 2004 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-15068864
18.
Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming.
Nat Immunol
; 5(12): 1260-5, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15531883
19.
Characterization of CC-chemokine receptor 7 expression on murine T cells in lymphoid tissues.
Immunology
; 110(2): 170-9, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14511230