Detalhe da pesquisa
1.
Pharmacophore Oriented MP2 Characterization of Charge Distribution for Anti-SARS-CoV-2 Inhibitor Nirmatrelvir.
J Mol Struct
; 1290: 135871, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37313328
2.
Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer.
Proteins
; 84(11): 1625-1643, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27481051
3.
Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior.
J Neurosci
; 33(4): 1615-30, 2013 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23345234
4.
The tilting motion of the central core reveals the transport mechanism of the sarco/endoplasmic reticulum Ca2+-ATPase.
Int J Biol Macromol
; 269(Pt 1): 132000, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38697445
5.
QM/MM study of N501 involved intermolecular interaction between SARS-CoV-2 receptor binding domain and antibody of human origin.
Comput Biol Chem
; 102: 107810, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36610304
6.
Heterotropic roles of divalent cations in the establishment of allostery and affinity maturation of integrin αXß2.
Cell Rep
; 40(8): 111254, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36001965
7.
Mechanistic role of NS4A and substrate in the activation of HCV NS3 protease.
Proteins
; 79(8): 2428-43, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21633972
8.
Antibody mix-and-read assays based on fluorescence intensity probes.
MAbs
; 13(1): 1980178, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34662534
9.
Impact of lymphoma-linked Asn11Tyr point mutation on the interaction between Bcl-2 and a BH3 mimetic: Insights from molecular dynamics simulation.
Chem Biol Drug Des
; 95(4): 435-450, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32030875
10.
Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands with Inverse Agonist and Degrader Activity.
ACS Chem Biol
; 15(11): 2916-2928, 2020 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33074669
11.
Computational insights into the interaction of the anthrax lethal factor with the N-terminal region of its substrates.
Proteins
; 75(2): 323-35, 2009 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18831046
12.
RNAdemocracy: an ensemble method for RNA secondary structure prediction using consensus scoring.
Comput Biol Chem
; 83: 107151, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31751879
13.
Insights into the substrate binding specificity of quorum-quenching acylase PvdQ.
J Mol Graph Model
; 88: 104-120, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30703686
14.
Immobilization and unbinding investigation of the antigen-antibody complex using theoretical and experimental techniques.
J Mol Graph Model
; 86: 219-227, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30388696
15.
Targeted reduction of the EGFR protein, but not inhibition of its kinase activity, induces mitophagy and death of cancer cells through activation of mTORC2 and Akt.
Oncogenesis
; 7(1): 5, 2018 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358623
16.
Nucleotide modification at the gamma-phosphate leads to the improved fidelity of HIV-1 reverse transcriptase.
Nucleic Acids Res
; 33(15): 4865-73, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16141194
17.
Dynamic pharmacophore model optimization: identification of novel HIV-1 integrase inhibitors.
J Med Chem
; 49(5): 1684-92, 2006 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16509584
18.
Functional Implications of the spectrum of BCL2 mutations in Lymphoma.
Mutat Res Rev Mutat Res
; 769: 1-18, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27543313
19.
Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds.
PLoS One
; 11(11): e0166477, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27829022
20.
Comparative molecular dynamics simulations of HIV-1 integrase and the T66I/M154I mutant: binding modes and drug resistance to a diketo acid inhibitor.
Proteins
; 59(4): 723-41, 2005 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15815973