Detalhe da pesquisa
1.
TREM2 drives microglia response to amyloid-ß via SYK-dependent and -independent pathways.
Cell
; 185(22): 4153-4169.e19, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36306735
2.
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy.
Cell
; 182(4): 886-900.e17, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32783918
3.
A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages.
Immunity
; 56(5): 1027-1045.e8, 2023 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36791722
4.
Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging.
Immunity
; 54(1): 99-115.e12, 2021 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33271118
5.
A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells.
Proc Natl Acad Sci U S A
; 120(52): e2318710120, 2023 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38109523
6.
Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
Proc Natl Acad Sci U S A
; 118(3)2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33446504
7.
Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease.
Glia
; 70(5): 935-960, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35092321
8.
Brain Parenchymal and Extraparenchymal Macrophages in Development, Homeostasis, and Disease.
J Immunol
; 204(2): 294-305, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31907272
9.
Activation of EP2 receptor suppresses poly(I: C) and LPS-mediated inflammation in primary microglia and organotypic hippocampal slice cultures: Contributing role for MAPKs.
Glia
; 66(4): 708-724, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29226424
10.
Fluorimetric detection of the earliest events in amyloid ß oligomerization and its inhibition by pharmacologically active liposomes.
Biochim Biophys Acta
; 1860(4): 746-56, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26774643
11.
Platinum-Based Drugs and DNA Interactions Studied by Single-Molecule and Bulk Measurements.
Biophys J
; 110(10): 2151-61, 2016 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27224480
12.
Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice.
Brain Behav Immun
; 55: 126-137, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26576722
13.
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model.
Sci Transl Med
; 16(741): eadj9052, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38569016
14.
Exploring the Impact of TREM2 in Tumor-Associated Macrophages.
Vaccines (Basel)
; 10(6)2022 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35746551
15.
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma.
Science
; 373(6553)2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34083447
16.
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders.
Science
; 373(6553)2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34083450
17.
Detection of Synaptic Proteins in Microglia by Flow Cytometry.
Front Mol Neurosci
; 13: 149, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33132837
18.
The CNS Immune-Privilege Goes Down the Drain(age).
Trends Pharmacol Sci
; 40(1): 1-3, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30528463
19.
Fifty Shades of Microglia.
Trends Neurosci
; 42(7): 440-443, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31005331
20.
Age-related myelin degradation burdens the clearance function of microglia during aging.
Nat Neurosci
; 19(8): 995-8, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27294511