[Alterations in several cerebral metabolic indices in patients with epilepsy]. / Izmenenie nekotorykh pokazatelei metabolizma golovnogo mozga u bol'nykh épilepsiei

The paper pertains to studies of some metabolic indices in the brain of 106 epileptic patients where fits were of a traumatical and inflammatory etiology and with the duration of the disease from 1-10 years. The examination revealed disorders of the reductive-oxidative processes and carbohydrate metabolism in the brain which were not related to the etiology of epilepsy. A disorder of reductive-oxidative processes were more expressed in focal nonconvulsive fits characteristic for temporal epilepsy. The authors point to a certain correlation between changes in biochemical indices and the duration of the disease.

[Glucose-6-phosphate dehydrogenase and transketolase activity in the blood of neurological oncologic patients preoperatively and in the dynamics of the postoperative period]. / Aktivnost' gliukozo-6-fosfatdegidrogenazy i transketolazy v krovi neiroonkologicheskikh bol'nykh do operatsii i v dinamike postoperatsionnogo periods.

Brain benign tumors /hypophyseal adenoma, meningeoma/ caused definite effects on the enzymes of pentosephosphate pathway in blood of patients. Distinct decrease in glucose-6-phosphate dehydrogenase /G6PD/ activity was observed in erythrocytes of patients with adenoma of hypophysis as compared with a control group; transketolase /TK/ activity was unaltered. In blood of patients with brain meningeomas the G6PD was activated by 8% and TK - by 36%. Within the first day after resection of the tumors activity of the enzymes was distinctly increased; it remained markedly higher than the enzymatic activity before the operation within all the periods studied /5-7 days and 10-15 days after the operation/.

[Time of formation of traumatic intracranial hematomas]. / Vremia obrazovaniia tramaticheskikh vnutricherepnykh gematom.

Biochemical study of the methemoglobin concentration (60 cases) and histological examination (40 of intracranial hematomas removed in different periods after the trauma confirmed the assumption that the main volume of these hematomas forms within the first minutes and hours after the trauma as a rule. The curve of the dependence of the methemoglobin concentration in the hematoma on the time of its formation allows the period of time which had elapsed after the trauma to be determined.

[Functions of the adrenal cortex in patients with supratentorial brain tumors and their prognostic value for surgical intervention]. / Funktsiia kory nadpochechnikov u bol'nykh s supratentorial'nymi opukholiami golovogo mozga i ee znachenie v prognoze prognoze operativnogo vmeshate'stva

The functional activity of the adrenal cortex was studied pre- and postoperatively in patients with pituitary adenomas, craiopharyngiomas and supratentorial meningiomas. With the hypothalamus function preserved, the patients developed varying degrees of stress-responses in the postoperative period. Severe morphological injuries to the hypothalamus make the normal response to surgical trauma impossible. With some functional centers preserved, the diencephalo-catabolic syndrome develops. Severe injuries of the diencephalon, with its adaptative function completely lost, result in the development of the diencephalic areactive syndrome.