Detalhe da pesquisa
1.
A randomized study of the safety and pharmacokinetics of GSK3358699, a mononuclear myeloid-targeted bromodomain and extra-terminal domain inhibitor.
Br J Clin Pharmacol
; 88(5): 2140-2155, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34773923
2.
Iridium(I) N-Heterocyclic Carbene (NHC)/Phosphine Catalysts for Mild and Chemoselective Hydrogenation Processes.
Chemistry
; 22(14): 4738-42, 2016 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26854284
3.
Hydrogen isotope exchange with highly active iridium(I) NHC/phosphine complexes: a comparative counterion study.
J Labelled Comp Radiopharm
; 59(14): 601-603, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27460856
4.
Iridium(I)-catalyzed regioselective C-H activation and hydrogen-isotope exchange of non-aromatic unsaturated functionality.
Chemistry
; 20(45): 14604-7, 2014 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25283156
5.
Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I-BET787.
J Med Chem
; 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38866424
6.
E- and Z-stereoselectivity in the preparation of enamides from glycidyl sulfonamides and carbamates.
Org Biomol Chem
; 10(3): 509-11, 2012 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22124587
7.
Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening.
J Med Chem
; 63(2): 714-746, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31904959
8.
The influence of experience and credential status on perceptions of agency competency in delivery of the 10 essential environmental public health services.
J Environ Health
; 72(3): 16-22, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19882987
9.
Highly active iridium(I) complexes for catalytic hydrogen isotope exchange.
Chem Commun (Camb)
; (9): 1115-7, 2008 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18292908
10.
Assessing histone demethylase inhibitors in cells: lessons learned.
Epigenetics Chromatin
; 10: 9, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28265301
11.
Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics.
ACS Chem Biol
; 11(7): 2002-10, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27197014
12.
Discovery of Tetrahydropyrazolopyridine as Sphingosine 1-Phosphate Receptor 3 (S1P3)-Sparing S1P1 Agonists Active at Low Oral Doses.
J Med Chem
; 59(3): 1003-20, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26751273
13.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.
J Med Chem
; 59(4): 1370-87, 2016 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26771203
14.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.
J Med Chem
; 59(4): 1357-69, 2016 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26771107
15.
Practical and efficient iridium catalysis for benzannulation: an entry to isoindolines.
ChemSusChem
; 5(10): 1888-91, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23001783
16.
Stereoselective Ir(III)-catalyzed dimerization reaction of enynes: an entry to functionalized polyunsaturated and cyclic systems.
Chem Commun (Camb)
; 46(34): 6332-4, 2010 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20676438
17.
New odourless protocols for efficient Pauson-Khand annulations.
Org Biomol Chem
; 3(13): 2396-8, 2005 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15976856