Detalhe da pesquisa
1.
Efficacy of Aminomethyl Spectinomycins against Complex Upper Respiratory Tract Bacterial Infections.
Antimicrob Agents Chemother
; 63(5)2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858215
2.
Activation of Exogenous Fatty Acids to Acyl-Acyl Carrier Protein Cannot Bypass FabI Inhibition in Neisseria.
J Biol Chem
; 291(1): 171-81, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26567338
3.
Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models.
J Antimicrob Chemother
; 72(3): 770-777, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27999020
4.
Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes.
J Antimicrob Chemother
; 71(4): 956-63, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26682963
5.
Synthesis and antibacterial evaluation of macrocyclic diarylheptanoid derivatives.
Bioorg Med Chem Lett
; 26(16): 4070-6, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27406794
6.
Synthesis and evaluation of pretomanid (PA-824) oxazolidinone hybrids.
Bioorg Med Chem Lett
; 26(2): 388-391, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26711150
7.
Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties.
Bioorg Med Chem
; 21(9): 2587-99, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23498915
8.
Three mitochondrial DNA polymerases are essential for kinetoplast DNA replication and survival of bloodstream form Trypanosoma brucei.
Eukaryot Cell
; 10(6): 734-43, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21531873
9.
Mitochondrial DNA polymerase POLIB is essential for minicircle DNA replication in African trypanosomes.
Mol Microbiol
; 75(6): 1414-25, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20132449
10.
Peptidomics of Haemonchus contortus.
ACS Omega
; 6(15): 10288-10305, 2021 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34056183
11.
Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives.
ACS Omega
; 3(12): 18343-18360, 2018 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30613820
12.
Design, synthesis and microbiological evaluation of ampicillin-tetramic acid hybrid antibiotics.
J Antibiot (Tokyo)
; 70(1): 65-72, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27189120
13.
Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions.
ACS Infect Dis
; 3(1): 72-88, 2017 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28081607
14.
In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis Antibiotics.
Sci Rep
; 5: 13985, 2015 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26365087
15.
Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections.
Sci Transl Med
; 7(288): 288ra75, 2015 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995221
16.
Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives.
J Med Chem
; 57(20): 8398-420, 2014 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25238443
17.
Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis.
PLoS One
; 9(2): e87909, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24505329
18.
Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux.
Nat Med
; 20(2): 152-158, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464186
19.
Syntheses and evaluation of macrocyclic engelhardione analogs as antitubercular and antibacterial agents.
J Antibiot (Tokyo)
; 66(6): 319-25, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23549356
20.
Silencing of a putative inner arm dynein heavy chain results in flagellar immotility in Trypanosoma brucei.
Mol Biochem Parasitol
; 175(1): 68-75, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20888370