Detalhe da pesquisa
1.
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
Nature
; 550(7677): 481-486, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045389
2.
Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility.
Bioorg Med Chem Lett
; 25(3): 529-41, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25556090
3.
Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
Bioorg Med Chem Lett
; 24(1): 337-43, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24279990
4.
Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg Med Chem Lett
; 23(20): 5488-97, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24021463
5.
Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties.
Bioorg Med Chem Lett
; 23(12): 3531-8, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23668988
6.
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Life Sci Alliance
; 3(8)2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32636217
7.
Synthesis, Equilibration, and Coupling of 4-Lithio-1,3-dioxanes: Synthons for syn- and anti-1,3-Diols.
J Org Chem
; 64(18): 6849-6860, 1999 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-11674695
8.
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
J Med Chem
; 56(12): 4921-37, 2013 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23617784
9.
Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors.
J Med Chem
; 56(16): 6413-33, 2013 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23859118
10.
Rational synthesis of contra-thermodynamic spiroacetals by reductive cyclizations.
J Am Chem Soc
; 127(2): 528-9, 2005 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-15643869