Detalhe da pesquisa
1.
ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension.
Am J Respir Crit Care Med
; 197(3): 373-385, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28910144
2.
Thioredoxin-2 inhibits mitochondrial reactive oxygen species generation and apoptosis stress kinase-1 activity to maintain cardiac function.
Circulation
; 131(12): 1082-97, 2015 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25628390
3.
Selective activation of protein kinase C∊ in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice.
J Neurosci Res
; 91(6): 799-807, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23426889
4.
An apoptosis signal-regulating kinase 1 inhibitor reduces cardiomyocyte apoptosis and infarct size in a rat ischemia-reperfusion model.
J Cardiovasc Pharmacol
; 60(3): 276-82, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22635076
5.
Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice.
Am J Physiol Cell Physiol
; 301(3): C577-86, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21677263
6.
Activation of PKCε-ALDH2 Axis Prevents 4-HNE-Induced Pain in Mice.
Biomolecules
; 11(12)2021 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34944441
7.
The Non-Steroidal FXR Agonist Cilofexor Improves Portal Hypertension and Reduces Hepatic Fibrosis in a Rat NASH Model.
Biomedicines
; 9(1)2021 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33435509
8.
Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors.
Sci Transl Med
; 13(616): eabe8939, 2021 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34669440
9.
Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout mice.
J Mol Cell Cardiol
; 48(4): 757-64, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19913552
10.
Apoptosis signal-regulating kinase 1 inhibition in in vivo and in vitro models of pulmonary hypertension.
Pulm Circ
; 10(2): 2045894020922810, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32523684
11.
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis.
Cell Rep
; 29(7): 1832-1847.e8, 2019 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31722201
12.
ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
J Clin Invest
; 128(10): 4485-4500, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30024858
13.
3'Phosphoinositide-dependent kinase-1 is essential for ischemic preconditioning of the myocardium.
FASEB J
; 20(14): 2556-8, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17077284
14.
17Beta-estradiol regulates expression of K(ATP) channels in heart-derived H9c2 cells.
J Am Coll Cardiol
; 40(2): 367-74, 2002 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12106946
15.
Hypoxia-induced preconditioning in adult stimulated cardiomyocytes is mediated by the opening and trafficking of sarcolemmal KATP channels.
FASEB J
; 18(9): 1046-8, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15084521
16.
Creatine kinase is physically associated with the cardiac ATP-sensitive K+ channel in vivo.
FASEB J
; 16(1): 102-4, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11729098
17.
Ageing is associated with a decrease in the number of sarcolemmal ATP-sensitive K+ channels in a gender-dependent manner.
Mech Ageing Dev
; 123(6): 695-705, 2002 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-11850031
18.
Mitigation of radiation-induced dermatitis by activation of aldehyde dehydrogenase 2 using topical alda-1 in mice.
Radiat Res
; 178(1): 69-74, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22404739
19.
Mitochondrial import of PKCepsilon is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury.
Cardiovasc Res
; 88(1): 83-92, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20558438
20.
Aldehyde dehydrogenase 2 in cardiac protection: a new therapeutic target?
Trends Cardiovasc Med
; 19(5): 158-64, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20005475