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Open Forum Infect Dis ; 9(9): ofac427, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-36111172

RESUMO

In this study, abnormal levels of myeloid activation, endothelial damage, and innate immune markers were associated with severe coronavirus disease 2019 (COVID-19), while higher levels of metabolic biomarkers (irisin, leptin) demonstrated a protective effect. These data support a model for COVID-19 immunopathogenesis linking robust inflammation and endothelial damage in metabolically predisposed individuals.

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