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Int J Clin Pharm ; 42(1): 89-99, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31792735

RESUMO

BACKGROUND: Chronic constipation is a prevalent issue in older people with intellectual disabilities and may have a significant negative impact on quality of life. The use of laxatives have not been adequately studied in this population. OBJECTIVE: To examine laxatives in relation to prevalence, pattern, dosage, reported indication and correlates. SETTING: Older people with intellectual disabilities who live independently, in community group homes or residential care in Ireland. METHOD: Data was extracted from wave 2 (2013/2014) of the Intellectual Disability Supplement to the Irish Longitudinal Study on Ageing (IDS-TILDA). Descriptive statistics, bivariate analyses and multiple logistic regression were carried out. Laxative use was analysed using two indicators for chronic constipation, reported doctor's diagnosis of constipation and Rome III criteria. MAIN OUTCOME MEASURE: Laxative use. RESULTS: Among the cohort n = 677, chronic constipation was reported by 38.5% (n = 257). In total 41.5% (n = 281) reported 431 laxatives (mean ± 1.53 ± 0.74), with 74.3% (n = 209) of those with laxative use reporting chronic constipation. There were 40% (n = 113) who took 2 + laxatives, within which, 60% (n = 67) were using a combination from same laxative class. Reporting chronic constipation, living in residential care, exposure to anticholinergics and receiving soft/liquidized food were significantly associated with laxative use. CONCLUSION: Chronic constipation and laxative use were highly prevalent in this study of older adults with intellectual disabilities. The treatment of constipation appeared to be unsystematic. Intra-class laxative use was frequent. There is a need for evidence-based treatment guidelines developed especially for people with intellectual disabilities to provide effective, quality care.


Assuntos
Constipação Intestinal/tratamento farmacológico , Constipação Intestinal/epidemiologia , Deficiência Intelectual/tratamento farmacológico , Deficiência Intelectual/epidemiologia , Laxantes/administração & dosagem , Adulto , Idoso , Estudos de Coortes , Constipação Intestinal/psicologia , Estudos Transversais , Feminino , Humanos , Deficiência Intelectual/psicologia , Irlanda/epidemiologia , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Distribuição Aleatória
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