Detalhe da pesquisa
1.
Photoaffinity labelling displacement assay using multiple recombinant protein domains.
Biochem J
; 480(15): 1183-1197, 2023 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37401534
2.
mRNA Display in Cell Lysates Enables Identification of Cyclic Peptides Targeting the BRD3 Extraterminal Domain.
Angew Chem Int Ed Engl
; : e202406414, 2024 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38899853
3.
Discrimination of textures with spatial correlations and multiple gray levels.
J Opt Soc Am A Opt Image Sci Vis
; 40(2): 237-258, 2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36821194
4.
A Chemo- and Regioselective Tandem [3 + 2]Heteroannulation Strategy for Carbazole Synthesis: Combining Two Mechanistically Distinct Bond-Forming Processes.
J Org Chem
; 87(7): 4603-4616, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35302774
5.
One-Step Synthesis of Photoaffinity Probes for Live-Cell MS-Based Proteomics.
Chemistry
; 27(71): 17880-17888, 2021 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34328642
6.
Quantitative MS-Based Proteomics: Comparing the MCF-7 Cellular Response to Hypoxia and a 2-Oxoglutarate Analogue.
Chembiochem
; 21(11): 1647-1655, 2020 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31919953
7.
A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands.
Angew Chem Int Ed Engl
; 59(47): 21096-21105, 2020 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32745361
8.
A Photoaffinity Displacement Assay and Probes to Study the Cyclin-Dependent Kinase Family.
Angew Chem Int Ed Engl
; 58(48): 17322-17327, 2019 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31518032
9.
Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition.
J Am Chem Soc
; 140(3): 932-939, 2018 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29232121
10.
YcfDRM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase.
Extremophiles
; 22(3): 553-562, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-29523972
11.
Studies on deacetoxycephalosporin C synthase support a consensus mechanism for 2-oxoglutarate dependent oxygenases.
Biochemistry
; 53(15): 2483-93, 2014 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24684493
12.
Covalent fragment-based drug discovery for target tractability.
Curr Opin Struct Biol
; 86: 102809, 2024 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38554479
13.
Novel WRN Helicase Inhibitors Selectively Target Microsatellite Unstable Cancer Cells.
Cancer Discov
; 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38587317
14.
Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry.
RSC Med Chem
; 14(4): 671-679, 2023 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37122547
15.
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome.
ACS Chem Biol
; 18(2): 285-295, 2023 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36649130
16.
Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments.
ACS Chem Biol
; 18(9): 1926-1937, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37084287
17.
Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery.
ACS Infect Dis
; 9(11): 2340-2357, 2023 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37906637
18.
Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation.
ACS Chem Biol
; 18(11): 2405-2417, 2023 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37874862
19.
A direct-to-biology high-throughput chemistry approach to reactive fragment screening.
Chem Sci
; 12(36): 12098-12106, 2021 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34667575
20.
Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase.
ACS Chem Biol
; 16(10): 1961-1967, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33835779