[Treatment of diffuse peritonitis in children].

THE PURPOSE OF THE STUDY: Improving the treatment of advanced peritonitis via use in therapy antihypoxant Reamberin and hepatoprotector Remaxol, nutritional support, sanitation laparoscopic abdominal cavity. SUBJECTS: A total of 232 children aged 1 to 15 years with generalized purulent peritonitis treated at the children's surgical departments of Samara from 2001 to 2014. A study group comprised 148 patients who used the optimized pathogenetic therapy. In the study group was allocated two groups: 64 patients in the pathogenetic therapy that used antihypoxant reamberin, and 84 children in the treatment of which reamberin and hepatoprotector remaxol. All the children of the main group received nutritional support (trophic feedings), used in the surgical treatment of abdominal laparoscopic sanitation. Comprehensive survey includes the study of the dynamics of the level of white blood cells, leukocyte index on Kalf-Caliph, erythrocyte sedimentation rate, temperature, total albumin concentration, transaminase levels. RESULTS: Comparison of the studied parameters in the study and control groups, showed a more rapid decrease in the symptoms and signs of intoxication (leukocytosis, LII, body temperature), relief of enteric disease, recovery of protein-synthetic function of the liver, a decrease of cytolytic and mesenchymal-inflammatory syndrome in the study group, especially in the subgroup in which therapy was included remaxol. CONCLUSIONS: Optimization of treatment involving the application of the combined drugs--antihypoxant reamberin, hepatoprotector remaxol, nutritional support and implementation of laparoscopic abdominal sanitation led to improved results of therapy common purulent peritonitis in children.

[The effect of low-intensity laser radiation on rat brain capillaries]. / Vliianie nizkointensivnogo lazernogo izlucheniia na kapilliary golovnogo mozga krys.

The dose-dependent action of the low-intensive He-Ne laser on the capillaries of the temporal area of the brain which were revealed by Mg ATPase has been determined. Laser radiation during 0.5-15 min provoked a complex of the activity of the enzymes in the vessels with density latent action of the factor. Subsequent increasing of the exposition (from 30 min to hours) bring to the opposite effect.

[The histochemical characteristics of the capillary bed of the brain in exposure to low-intensity laser radiation]. / Gistokhimicheskaia kharakteristika kapilliarnogo rusla golovnogo mozga pri vozdeistvii nizkointensivnogo lazernogo izlucheniia.

Rat brain was exposed to He-Ne laser at wavelength 632.8 nm, power density 0.76 mWt/cm2. Hippocampal capillaries detected by alkaline phosphatase were examined in various periods (from 1 sec to 3 h) after the exposure. Changes of the enzyme activity in capillary walls, capillary length and diameter were examined after laser exposures of various duration. Enzymic activity and total capillary length were found to increase within the first 15 min of irradiation by 1.5-2 times. A longer irradiation resulted in reduction of these parameters. Capillary diameter changed negligibly after 15-min exposure, and after a longer irradiation a stable dilatation of capillaries was observed.