[Clinical observation of visual quality after the individual implantation of intraocular lens guided by corneal Q value].

Objective: To describe the feasibility of individual IOL implantation guided by corneal Q value and observe patients postoperative visual quality under different residual spherical aberration. Methods: Prospective study. One hundred and twenty cases (171 eyes)cataract patients in our hospital were selected for the individual implantation of intraocular lens guided by corneal Q value which obtained by Oberscan before operation. Based on spherical aberration calculated by corneal Q value, choose appropriate IOL personalitily to make postoperative whole eye surface aberration +0.1 µm (group of positive spherical aberration) or 0 µm (group of zero spherical aberration). To observe spherical aberration, the uncorrected visual acuity, best corrected visual acuity and contrast sensitivity (including no glare and glare) 1 month and 3 months after surgery. Dates were analyzed with one-way ANOVA and LSD method for multiple comparisons between groups. Results: Spherical aberration after operation: group of positive spherical aberration: (0.111±0.023)µm, group of zero spherical aberration: (0.020±0.019)µm, control group: (0.299±0.073)µm. At 1 months and 3 months, uncorrected visual acuity, and corrected visual acuity were not statistically different between groups (t=0.474, 1.607, P>0.05). Contrast sensitivity (including no glare and glare) 3 months after surgery display: at whole space frequency, the group of positive spherical aberration(reserved +0.1 µm spherical aberration) contrast sensitivity is better than that of the group of zero spherical aberration(reserved 0.0 µm spherical aberration) and the control group(F=32.885, 35.493, 19.969, 20.572,P<0.05). The group of zero spherical aberration is better than control group at space frequency of 3 and 6 c/d(F=6.506, 7.521, P<0.05). Conclusions: The individual implantation of introcular lens guided by corneal Q value is feasible. + 0.1 µm spherical aberration after surgery can achieve the best contrast sensitivity and stereo vision, and 0 spherical aberration after surgery can improve the postoperative contrast sensitivity and stereo vision than a traditional method, but its advantage mainly embodies in the middle and lower spatial frequency. (Chin J Ophthalmol, 2017, 53: 814-820).

[Effect of tonsillar macrophages on several immune functions].

Effect of tonsillar macrophages on IL2 responsiveness of T cells, IFN production, T cell proliferation and NK cell activity was studied. Human tonsillar mononuclear cells (TMNC) were purified by a two-step procedure which included depletion of plastic-adherent cells and rosetting with sheep blood cells. The production of IFN by enriched T cells (ETC) and IL2 responsiveness of ETC deprived of macrophages were decreased, whereas T cell proliferation in response to PHA stimulation, and NK cell activity in ETC were enhanced. These results imply that the IL2 responsiveness, IFN production, T cell proliferation and NK cell activity in ETC are influenced by macrophages.