Detalhe da pesquisa
1.
Mini PROTACs: N-end rule-mediated degradation on the horizon.
Trends Biochem Sci
; 49(1): 5-7, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37923612
2.
PPI-Miner: A Structure and Sequence Motif Co-Driven Protein-Protein Interaction Mining and Modeling Computational Method.
J Chem Inf Model
; 62(23): 6160-6171, 2022 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36448715
3.
CRL4 antagonizes SCFFbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory.
PLoS Genet
; 14(1): e1007165, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29370161
4.
Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase.
J Biol Chem
; 292(9): 3683-3691, 2017 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28087699
5.
A mouse model of a human congenital disorder of glycosylation caused by loss of PMM2.
Hum Mol Genet
; 25(11): 2182-2193, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27053713
6.
Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy.
Proc Natl Acad Sci U S A
; 112(51): 15666-71, 2015 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26644582
7.
ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis.
Proc Natl Acad Sci U S A
; 112(29): 9088-93, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26150517
8.
A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.
J Inherit Metab Dis
; 39(6): 807-820, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27469509
9.
c-Abl tyrosine kinase regulates cardiac growth and development.
Proc Natl Acad Sci U S A
; 107(3): 1136-41, 2010 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080568
10.
Hepatocyte-specific deletion of DDB1 induces liver regeneration and tumorigenesis.
Proc Natl Acad Sci U S A
; 107(51): 22237-42, 2010 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21135245
11.
Addressing the Enzyme-independent tumor-promoting function of NAMPT via PROTAC-mediated degradation.
Cell Chem Biol
; 29(11): 1616-1629.e12, 2022 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36323324
12.
Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling.
Cell Chem Biol
; 29(8): 1260-1272.e8, 2022 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35732177
13.
Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum.
J Neurosci
; 30(43): 14430-9, 2010 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20980600
14.
[Application of WAIS-RC short forms and adult intelligence disability scale in mental impairment assessment].
Fa Yi Xue Za Zhi
; 27(3): 189-92, 2011 Jun.
Artigo
em Chinês
| MEDLINE | ID: mdl-21899009
15.
ERK signaling mediates resistance to immunomodulatory drugs in the bone marrow microenvironment.
Sci Adv
; 7(23)2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34088671
16.
Tumor evolution selectively inactivates the core microRNA machinery for immune evasion.
Nat Commun
; 12(1): 7003, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853298
17.
Safe and effective subcutaneous adipolysis in minipigs by a collagenase derivative.
PLoS One
; 14(12): e0227202, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31891643
18.
A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity.
Leukemia
; 33(1): 171-180, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30026574
19.
Restriction of hepatitis B virus replication by c-Abl-induced proteasomal degradation of the viral polymerase.
Sci Adv
; 5(2): eaau7130, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30775435
20.
CRL4DCAF8 Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver.
Cell Rep
; 18(6): 1499-1511, 2017 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28178526