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1.
Sensors (Basel) ; 24(16)2024 Aug 20.
Artigo em Inglês | MEDLINE | ID: mdl-39205058

RESUMO

Electromagnetic tracking (EMT) can benefit image-guided interventions in cases where line of sight is unavailable. However, EMT can suffer from electromagnetic distortion in the presence of metal instruments. Metal instruments are widely used in laparoscopic surgery, ENT surgery, arthroscopy and many other clinical applications. In this work, we investigate the feasibility of tracking such metal instruments by placing the inductive sensor within the instrument shaft. We propose a magnetostatic model of the field within the instrument, and verify the results experimentally for frequencies from 6 kHz to 60 kHz. The impact of the instrument's dimensions, conductivity and transmitting field frequency is quantified for ranges representative of typical metal instruments used in image-guided interventions. We then performed tracking using the open-source Anser EMT system and quantify the error caused by the presence of the rod as a function of the frequency of the eight emitting coils for the system. The work clearly demonstrates why smaller tool diameters (less than 8 mm) are less susceptible to distortion, as well as identifying optimal frequencies (1 kHz to 2 kHz) for transmitter design to minimise for distortion in larger instruments.


Assuntos
Metais , Metais/química , Humanos , Cirurgia Assistida por Computador/métodos , Cirurgia Assistida por Computador/instrumentação , Magnetismo/instrumentação , Desenho de Equipamento , Campos Eletromagnéticos
2.
Minim Invasive Ther Allied Technol ; 31(7): 1050-1057, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-36107490

RESUMO

Objective: This work presents the results of Benchtop tests and pre-clinical study of a novel design for a foldable magnetic anastomosis device. The device can be deployed through an endoscope device channel and fold into a ring larger than the deployment port. This new design enables the target application in JJ-anastomosis creation.Material and methods: The folding anastomosis device is constructed from a chain of permanent magnets suspended in a suture weaving inspired by the contact-aided compliant mechanisms. The device was deployed through an endoscope in Benchtop experiments and its expected coupling force was measured in a pull test. A set of experiments was executed during the pre-clinical study, where the device was deployed in the abdomen, to estimate the reliability of deployment and the plausibility of the use in jejuno-jejunal (JJ)- and gastrojejunal (GJ)-anastomosis creation.Results: The presented folding anastomosis device was shown to deploy through an endoscope device channel and a catheter with an inner diameter of 3.2 mm. After deployment the device folds reliably into a ring with an outer diameter of 7-8 mm. The folded device was shown to exhibit a coupling force comparable to similar cases of JJ-anastomosis creation. It is concluded that the presented design of a folding magnetic ring is suitable for select cases of magnetic compression anastomosis where the device is either delivered through a catheter to fold into an anastomosis ring larger than the deployment port or through an endoscopes device channel to allow for convenient visual confirmation of the device during placement.


Assuntos
Imãs , Procedimentos Cirúrgicos Minimamente Invasivos , Anastomose Cirúrgica/métodos , Desenho de Equipamento , Fenômenos Magnéticos , Reprodutibilidade dos Testes
3.
Sensors (Basel) ; 21(8)2021 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-33923811

RESUMO

Electromagnetic tracking is a safe, reliable, and cost-effective method to track medical instruments in image-guided surgical navigation. However, patient motion and magnetic field distortions heavily impact the accuracy of tracked position and orientation. The use of redundant magnetic sensors can help to map and mitigate for patient movements and magnetic field distortions within the tracking region. We propose a planar inductive sensor design, printed on PCB and embedded into medical patches. The main advantage is the high repeatability and the cost benefit of using mass PCB manufacturing processes. The article presents new operative formulas for electromagnetic tracking of planar coils on the centimetre scale. The full magnetic analytical model is based on the mutual inductance between coils which can be approximated as being composed by straight conductive filaments. The full model is used to perform accurate system simulations and to assess the accuracy of faster simplified magnetic models, which are necessary to achieve real-time tracking in medical applications.


Assuntos
Fenômenos Eletromagnéticos , Cirurgia Assistida por Computador , Humanos , Campos Magnéticos
4.
Sensors (Basel) ; 21(10)2021 May 12.
Artigo em Inglês | MEDLINE | ID: mdl-34065968

RESUMO

In recent times, the use of electromagnetic tracking for navigation in surgery has quickly become a vital tool in minimally invasive surgery. In many procedures, electromagnetic tracking is used in tandem with X-ray technology to track a variety of tools and instruments. Most commercially available EM tracking systems can cause X-ray artifacts and attenuation due to their construction and the metals that form them. In this work, we provide a novel solution to this problem by creating a new radiolucent electromagnetic navigation system that has minimal impact on -ray imaging systems. This is a continuation of our previous work where we showed the development of the Anser open-source electromagnetic tracking system. Typical electromagnetic tracking systems operate by generating low frequency magnetic fields from coils that are located near the patient. These coils are typically made from copper, steel, and other dense radiopaque materials. In this work, we explore the use of low density aluminum to create these coils and we demonstrate that the effect on X-ray images is significantly reduced as a result of these novel changes in the materials used. The resulting field generator is shown to give at least a 60% reduction in the X-ray attenuation in comparison to our earlier designs. We verify that the system accuracy of approximately 1.5 mm RMS error is maintained with this change in design.


Assuntos
Cirurgia Assistida por Computador , Fenômenos Eletromagnéticos , Humanos , Imagens de Fantasmas , Radiografia , Raios X
5.
Minim Invasive Ther Allied Technol ; 28(6): 363-372, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30428748

RESUMO

Objectives: The goal was to demonstrate the utility of open-source tracking and visualisation tools in the targeting of lung cancer.Material and methods: The study demonstrates the first deployment of the Anser electromagnetic (EM) tracking system with the CustusX image-guided interventional research platform to navigate using an endobronchial catheter to injected tumour targets. Live animal investigations validated the deployment and targeting of peripheral tumour models using an innovative tumour marking routine.Results: Novel tumour model deployment was successfully achieved at all eight target sites across two live animal investigations without pneumothorax. Virtual bronchoscopy with tracking successfully guided the tracked catheter to 2-12 mm from the target tumour site. Deployment of a novel marker was achieved at all eight sites providing a reliable measure of targeting accuracy. Targeting accuracy within 10 mm was achieved in 7/8 sites and in all cases, the virtual target distance at marker deployment was within the range subsequently measured with x-ray.Conclusions: Endobronchial targeting of peripheral airway targets is feasible using existing open-source technology. Notwithstanding the shortcomings of current commercial platforms, technological improvements in EM tracking and registration accuracy fostered by open-source technology may provide the impetus for widespread clinical uptake of electromagnetic navigation in bronchoscopy.


Assuntos
Broncoscopia/métodos , Fenômenos Eletromagnéticos , Neoplasias Pulmonares/diagnóstico , Animais , Feminino , Suínos
6.
Sensors (Basel) ; 18(9)2018 Sep 12.
Artigo em Inglês | MEDLINE | ID: mdl-30213100

RESUMO

Electromagnetic tracking (EMT) is playing an increasingly important role in surgical navigation, medical robotics and virtual reality development as a positional and orientation reference. Though EMT is not restricted by line-of-sight requirements, measurement errors caused by magnetic distortions in the environment remain the technology's principal shortcoming. The characterisation, reduction and compensation of these errors is a broadly researched topic, with many developed techniques relying on auxiliary tracking hardware including redundant sensor arrays, optical and inertial tracking systems. This paper describes a novel method of detecting static magnetic distortions using only the magnetic field transmitting array. An existing transmitter design is modified to enable simultaneous transmission and reception of the generated magnetic field. A mutual inductance model is developed for this transmitter design in which deviations from control measurements indicate the location, magnitude and material of the field distorter to an approximate degree. While not directly compensating for errors, this work enables users of EMT systems to optimise placement of the magnetic transmitter by characterising a distorter's effect within the tracking volume without the use of additional hardware. The discrimination capabilities of this method may also allow researchers to apply material-specific compensation techniques to minimise position error in the clinical setting.

8.
Biomed Eng Online ; 14: 62, 2015 Jun 26.
Artigo em Inglês | MEDLINE | ID: mdl-26112975

RESUMO

BACKGROUND: Computed tomography (CT) helps physicians locate and diagnose pathological conditions. In some conditions, having an airway segmentation method which facilitates reconstruction of the airway from chest CT images can help hugely in the assessment of lung diseases. Many efforts have been made to develop airway segmentation algorithms, but methods are usually not optimized to be reliable across different CT scan parameters. METHODS: In this paper, we present a simple and reliable semi-automatic algorithm which can segment tracheal and bronchial anatomy using the open-source 3D Slicer platform. The method is based on a region growing approach where trachea, right and left bronchi are cropped and segmented independently using three different thresholds. The algorithm and its parameters have been optimized to be efficient across different CT scan acquisition parameters. The performance of the proposed method has been evaluated on EXACT'09 cases and local clinical cases as well as on a breathing pig lung phantom using multiple scans and changing parameters. In particular, to investigate multiple scan parameters reconstruction kernel, radiation dose and slice thickness have been considered. Volume, branch count, branch length and leakage presence have been evaluated. A new method for leakage evaluation has been developed and correlation between segmentation metrics and CT acquisition parameters has been considered. RESULTS: All the considered cases have been segmented successfully with good results in terms of leakage presence. Results on clinical data are comparable to other teams' methods, as obtained by evaluation against the EXACT09 challenge, whereas results obtained from the phantom prove the reliability of the method across multiple CT platforms and acquisition parameters. As expected, slice thickness is the parameter affecting the results the most, whereas reconstruction kernel and radiation dose seem not to particularly affect airway segmentation. CONCLUSION: The system represents the first open-source airway segmentation platform. The quantitative evaluation approach presented represents the first repeatable system evaluation tool for like-for-like comparison between different airway segmentation platforms. Results suggest that the algorithm can be considered stable across multiple CT platforms and acquisition parameters and can be considered as a starting point for the development of a complete airway segmentation algorithm.


Assuntos
Algoritmos , Broncografia , Processamento de Imagem Assistida por Computador/métodos , Software , Tomografia Computadorizada por Raios X , Traqueia/diagnóstico por imagem , Animais , Brônquios/fisiologia , Humanos , Respiração , Suínos , Traqueia/fisiologia
9.
BMC Med Educ ; 14: 14, 2014 Jan 22.
Artigo em Inglês | MEDLINE | ID: mdl-24450310

RESUMO

BACKGROUND: Healthcare worldwide needs translation of basic ideas from engineering into the clinic. Consequently, there is increasing demand for graduates equipped with the knowledge and skills to apply interdisciplinary medicine/engineering approaches to the development of novel solutions for healthcare. The literature provides little guidance regarding barriers to, and facilitators of, effective interdisciplinary learning for engineering and medical students in a team-based project context. METHODS: A quantitative survey was distributed to engineering and medical students and staff in two universities, one in Ireland and one in Belgium, to chart knowledge and practice in interdisciplinary learning and teaching, and of the teaching of innovation. RESULTS: We report important differences for staff and students between the disciplines regarding attitudes towards, and perceptions of, the relevance of interdisciplinary learning opportunities, and the role of creativity and innovation. There was agreement across groups concerning preferred learning, instructional styles, and module content. Medical students showed greater resistance to the use of structured creativity tools and interdisciplinary teams. CONCLUSIONS: The results of this international survey will help to define the optimal learning conditions under which undergraduate engineering and medicine students can learn to consider the diverse factors which determine the success or failure of a healthcare engineering solution.


Assuntos
Atitude do Pessoal de Saúde , Educação Médica/métodos , Engenharia/educação , Docentes de Medicina , Estudos Interdisciplinares , Aprendizagem Baseada em Problemas/métodos , Estudantes de Medicina/psicologia , Ensino/métodos , Adulto , Bélgica , Engenharia/métodos , Feminino , Humanos , Irlanda , Masculino , Pessoa de Meia-Idade , Estudantes/psicologia , Inquéritos e Questionários , Adulto Jovem
10.
Surg Innov ; 21(1): 65-73, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23592733

RESUMO

AIM: The concept of compression alimentary anastomosis is well established. Recently, magnetic axial alignment pressures have been encompassed within such device constructs. We quantify the magnetic compression force and pressure required to successfully achieve gastrointestinal and bilioenteric anastomosis by in-depth interrogation of the reported literature. METHODS: Reports of successful deployment and proof of anastomotic patency on survival were scrutinized to quantify the necessary dimensions and strengths of magnetic devices in (a) gastroenteral anastomosis in live porcine models and (b) bilioenteric anastomosis in the clinical setting. Using a calculatory tool developed for this work (magnetic force determination algorithm, MAGDA), ideal magnetic force and compression pressure were quantified from successful reports with regard to their variance by intermagnet separation. RESULTS: Optimized ranges for both compression force and pressure were determined for successful porcine gastroenteral and clinical bilioenteric anastomoses. For gastroenteral anastomoses (porcine investigations), an optimized compression force between 2.55 and 3.57 kg at 2-mm intermagnet separation is recommended. The associated compression pressure should not exceed 60 N/cm(2). Successful bilioenteric anastomoses is best clinically achieved with intermagnet compression of 18 to 31 g and associated pressures between 1 and 3.5 N/mm(2) (at 2-mm intermagnet separation). CONCLUSION: The creation of magnetic compression anastomoses using permanent magnets demonstrates a remarkable resilience to variations in magnetic force and pressure exertion. However, inappropriate selection of compression characteristics and magnet dimensions may incur difficulties. Recommendations of this work and the availability of the free online tool (http://magda.ucc.ie/) may facilitate a factor of robustness in the design and refinement of future devices.


Assuntos
Anastomose Cirúrgica/instrumentação , Procedimentos Cirúrgicos do Sistema Biliar/instrumentação , Procedimentos Cirúrgicos do Sistema Digestório/instrumentação , Magnetismo , Algoritmos , Animais , Humanos , Modelos Animais , Pressão , Software , Suínos
11.
Int J Comput Assist Radiol Surg ; 19(1): 27-31, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37501053

RESUMO

PURPOSE: Electromagnetic tracking (EMT) accuracy is affected by the presence of surrounding metallic materials. In this work, we propose measuring the magnetic field's variation due to distortion at a witness position to localise the instrument causing distortion based on a pre-trained model and without additional sensors attached to it. METHODS: Two experiments were performed to demonstrate possible applications of the technique proposed. In the first case, the distortion introduced by an ultrasound (US) probe was characterised and subsequently used to track the probe position on a line. In the second application, the measurement was used to estimate the distance of an interventional fluoroscopy C-arm machine and apply the correct compensation model. RESULTS: Tracking of the US probe using the proposed method was demonstrated with millimetric accuracy. The distortion created by the C-arm caused errors in the order of centimetres, which were reduced to 1.52 mm RMS after compensation. CONCLUSIONS: The distortion profile associated with medical equipment was pre-characterised and used in applications such as object tracking and error compensation map selection. In the current study, the movement was limited to one degree of freedom (1 DOF) and simple analytical functions were used to model the magnetic distortion. Future work will explore advanced AI models to extend the method to 6 DOF tracking using multiple witness sensors.


Assuntos
Cirurgia Assistida por Computador , Humanos , Cirurgia Assistida por Computador/métodos , Fenômenos Eletromagnéticos , Ultrassonografia , Fluoroscopia
12.
Artigo em Inglês | MEDLINE | ID: mdl-38568765

RESUMO

This paper presents a compact and low-cost on-chip sensor and readout circuit. The sensor achieves high-resolution 5-degrees-of-freedom (DoF) tracking (x, y, z, yaw, and pitch). With the help of an external wire wound sensor, it can also achieve high-resolution 6-degrees-of-freedom (DoF) tracking (x, y, z, yaw, pitch, and roll angles). The sensor uses low-frequency magnetic fields to detect the position and orientation of instruments, providing a viable alternative to using X-rays in image-guided surgery. To measure the local magnetic field, a highly miniaturised on-chip magnetic sensor capable of sensing the magnetic field has been developed incorporating an on-chip magnetic sensor coil, analog-front end, continuous-time ΔΣ analog-to-digital converter (ADC), LVDS transmitter, bandgap reference, and voltage regulator. The microchip is fabricated using 65 nm CMOS technology and occupies an area of 1.06 mm2, the smallest reported among similar designs to the best of our knowledge. The 5-DoF system accurately navigates with a precision of 1.1 mm within the volume-of-intrest (VOI) of 15×15×15 cm3. The 6-DoF system achieves a navigation accuracy of 0.8 mm and an angular error of 1.1 degrees in the same VOI. These results were obtained at a 20 Hz update rate in benchtop characterisation. The prototype sensor demonstrates accurate position tracking in real-life pre-clinical in-vivo settings within the porcine lung of a live swine, achieving a reported worst-case registration accuracy of 5.8 mm.

13.
Int J Comput Assist Radiol Surg ; 18(9): 1707-1713, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37386335

RESUMO

PURPOSE: Electromagnetic tracking (EMT) is beneficial in image-guided interventions to reduce the use of ionising radiation-based imaging techniques. Enabling wirelessly tracked sensors will increase the usability of these systems for catheter tracking and patient registration systems. This work introduces a novel method of wirelessly transmitting sensor data using a frequency modulation (FM) radio. METHODS: The proposed technique was tested using the open-source Anser EMT system. An electromagnetic sensor was connected in parallel to an FM transmitter prototype and wired directly to the Anser system for comparison. The performance of the FM transmitter was evaluated on a grid of 125 test points using an optical tracking system as a gold standard. RESULTS: An average position accuracy of 1.61 ± 0.68 mm and angular rotation accuracy of 0.04° for the FM transmitted sensor signal was obtained over a 30 cm × 30 cm × 30 cm volume, in comparison with the 1.14 ± 0.80 mm, 0.04° accuracy previously reported for the Anser system. The FM transmitted sensor signal had an average resolved position precision of 0.95 mm while the directly wired signal was found to have an average precision of 1.09 mm. A very low frequency (∼ 5 mHz) oscillation in the wirelessly transmitted signal was observed and compensated for by performing a dynamic scaling of the magnetic field model used for solving the sensor pose. CONCLUSIONS: We demonstrate that FM transmission of an electromagnetic sensor signal can be used to achieve similar tracking performance to a wired sensor. FM transmission for wireless EMT is a viable alternative to digital sampling and transmission over Bluetooth. Future work will create an integrated wireless sensor node using FM communication that is compatible with existing EMT systems.


Assuntos
Fenômenos Eletromagnéticos , Cirurgia Assistida por Computador , Humanos , Catéteres , Cirurgia Assistida por Computador/métodos , Campos Magnéticos , Sistemas Computacionais
14.
J Biomed Opt ; 28(3): 035002, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-37009578

RESUMO

Significance: As clinical evidence on the colorectal application of indocyanine green (ICG) perfusion angiography accrues, there is also interest in computerizing decision support. However, user interpretation and software development may be impacted by system factors affecting the displayed near-infrared (NIR) signal. Aim: We aim to assess the impact of camera positioning on the displayed NIR signal across different open and laparoscopic camera systems. Approach: The effects of distance, movement, and target location (center versus periphery) on the displayed fluorescence signal of different systems were measured under electromagnetic stereotactic guidance from an ICG-albumin model and in vivo during surgery. Results: Systems displayed distinct fluorescence performances with variance apparent with scope optical lens configuration (0 deg versus 30 deg), movement, target positioning, and distance. Laparoscopic system readings fitted inverse square function distance-intensity curves with one device and demonstrated a direction dependent sigmoid curve. Laparoscopic cameras presented central targets as brighter than peripheral ones, and laparoscopes with angled optical lens configurations had a diminished field of view. One handheld open system also showed a distance-intensity relationship, whereas the other maintained a consistent signal despite distance, but both presented peripheral targets brighter than central ones. Conclusions: Optimal clinical use and signal computational development requires detailed appreciation of system behaviors.


Assuntos
Verde de Indocianina , Laparoscopia , Angiografia , Fluorescência , Espectroscopia de Luz Próxima ao Infravermelho
15.
Gastrointest Endosc ; 75(4): 888-892.e1, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22226385

RESUMO

BACKGROUND: Plastic stents are routinely placed in the pancreaticobiliary system to facilitate drainage. A second endoscopy is often required for stent removal. We have developed magnetic pancreaticobiliary stents that can be removed by using an external hand-held magnet, thereby obviating the need for a second endoscopy. OBJECTIVE: To develop and test magnetic pancreaticobiliary stents and retrieval system in ex-vivo and in-vivo porcine models. SETTING: Animal laboratory. DESIGN: Benchtop and animal study. ANIMALS: 5 pigs. INTERVENTIONS: Design: Computer simulations determined both the optimal design of cylindrical magnets attached to the distal aspect of existing plastic stents and the optimal design of the external hand-held magnet. Benchtop ex-vivo experiments measured magnetic force to validate the design. In-vivo analysis: In 5 Yorkshire pigs, magnetic stents were deployed into the common bile duct by using a conventional duodenoscope. An external hand-held magnet was applied for stent removal. Stent insertion and removal times were recorded. MAIN OUTCOME MEASUREMENTS: Technical feasibility. RESULTS: Magnetic stents of varying lengths and calibers were successfully created. In ex-vivo testing, the capture distance was 10.0 cm. During in-vivo testing, the magnetic stents were inserted and removed easily. The mean insertion and removal times were 3.2 minutes and 33 seconds, respectively. LIMITATIONS: Animal study, small numbers. CONCLUSIONS: Magnetic pancreaticobiliary stents and associated retrieval system were successfully designed and tested in the acute porcine model. An external, noninvasive means of stent removal potentially obviates the need for a second endoscopy, which could represent a major gain both for patients and in health care savings.


Assuntos
Remoção de Dispositivo/métodos , Imãs , Stents , Animais , Ducto Colédoco , Estudos de Viabilidade , Implantação de Prótese , Suínos , Fatores de Tempo
16.
Int J Comput Assist Radiol Surg ; 17(9): 1717-1721, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35599296

RESUMO

PURPOSE: Hybrid navigation is a promising technique which combines the benefits of optical or electromagnetic tracking (EMT) and fluoroscopy imaging. Unfortunately, the fluoroscopy system is a source of metallic distortion for the EMT system. In this work, we present a new method for intraoperative calibration and real-time compensation of dynamic field distortions. The method was tested in the presence of a fluoroscopy C-arm, and sub-millimetre errors were obtained after distortion correction. METHODS: A hybrid navigation scenario was created by combining the open-source electromagnetic tracking system Anser EMT and a commercial fluoroscopy C-arm. The electromagnetic field generator was placed directly on top of the X-ray collimator, which introduced significant field distortion. Magnetic sensors were placed at known positions to capture the magnetic distortion, and virtual magnetic dipole sources were used to model the distortion magnetic field. The accuracy of the compensated EMT model was tested on a grid of test points. RESULTS: Error reduction was demonstrated from 12.01 to 0.35 mm and from 25.03 to 0.49 mm, for horizontal and vertical sensor orientations, respectively, over a volume of 16 × 16 × 6 cm. It is proposed that such sub-millimetre tracking errors meet the needs of most endoscopic navigation tasks. CONCLUSIONS: We describe a method to model a magnetic field in real time, based on redundant electromagnetic field measurements, and we apply it to compensate for the distortion introduced by a fluoroscopy C-arm. The main limitation of the approach is the requirement for a high number of sensors, with possible occlusion of the operative space. Solutions might come from miniaturisation and wireless sensing.


Assuntos
Fenômenos Eletromagnéticos , Cirurgia Assistida por Computador , Calibragem , Campos Eletromagnéticos , Fluoroscopia , Humanos , Cirurgia Assistida por Computador/métodos
17.
Gastrointest Endosc ; 73(2): 353-9, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21183179

RESUMO

BACKGROUND: Gastrojejunostomy is important for palliation of malignant gastric outlet obstruction and surgical obesity procedures. A less-invasive endoscopic technique for gastrojejunostomy creation is conceptually attractive. Our group has developed a compression anastomosis technology based on endoscopically delivered self-assembling magnets for endoscopy (SAMSEN) to create an instant, large-caliber gastrojejunostomy. OBJECTIVE: To develop and evaluate an endoscopic means of gastrojejunostomy creation by using SAMSEN. SETTING: Developmental laboratory and animal facility. DESIGN: Animal study and human cadaveric study. SUBJECTS: Yorkshire pigs (7 cadaver, 5 acute); human (1 cadaver). INTERVENTIONS: A transoral procedure for SAMSEN delivery was developed in porcine and human cadaver models. Subsequently, gastrojejunostomy creation by using SAMSEN was performed in 5 acute pigs. The endoscope was advanced into the peritoneal cavity through the gastrotomy, and a segment of the small bowel was grasped and pulled closer to the stomach. An enterotomy was created, and a custom overtube was advanced into the small bowel for deployment of the first magnetic assembly. Next, a reciprocal magnetic assembly was deployed in the stomach. The 2 magnetic systems were mated under fluoroscopic and endoscopic guidance. Contrast studies assessed for gastrojejunostomy leak. Immediate necropsies were performed. MAIN OUTCOME MEASUREMENTS: Technical feasibility and complications. RESULTS: Gastrojejunostomy creation by using SAMSEN was successful in all 5 animals. Deep enteroscopy was performed through the stoma without difficulty. No leaks were identified on contrast evaluation. At necropsy, the magnets were properly deployed and robustly coupled together, resistant to vigorous tissue manipulation. LIMITATIONS: Acute animal study. CONCLUSIONS: Endoscopic creation of immediate gastrojejunostomy by using SAMSEN is technically feasible.


Assuntos
Endoscópios Gastrointestinais , Endoscopia Gastrointestinal/métodos , Derivação Gástrica/métodos , Obstrução da Saída Gástrica/cirurgia , Magnetismo/instrumentação , Animais , Cadáver , Modelos Animais de Doenças , Desenho de Equipamento , Humanos , Reprodutibilidade dos Testes , Suínos
19.
Simul Healthc ; 15(3): 214-220, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32487840

RESUMO

INTRODUCTION: The aims of this study were to test a novel simulation platform suitable for flexible cystoscopy using a standard scope, to assess the platform's proposed use as a training tool for flexible cystoscopy, and to assess the user experience through surveyed response. METHODS: Thirty-one urologists (11 novices, 20 experts) were evaluated using a novel light-based bladder model and standard flexible cystoscope. Time to complete full inspection of the simulated bladder was measured, and the scope trajectory was recorded. Participants also completed a survey of the training platform. RESULTS: Thirty participants completed a simulated inspection of a portable bladder model with a mean ± SD time for 153.1 ± 76.1 seconds. One participant failed to complete. Novice urologists (defined as those having completed less than 50 flexible cystoscopies in clinic) had a mean ± SD time of 176.9 ± 95.8 seconds, whereas with experts, this decreased to 139.3 ± 60.7 seconds. Dynamic trajectory maps identified "blind spots" within each user's cystoscopy performance. In a poststudy follow-up, 27 participants considered the tool valuable or extremely valuable for training, whereas 19 participants considered that the tool either very well or excellently replicated the clinical setting. All participants ranked the tool as very good or excellent for overall quality of training. DISCUSSION: Advances in electronic technology make portable low-cost models a potential low-cost alternative to endourology training platforms. In providing a quantifiable measure of user performance, the tool may shorten the learning curve in flexible cystoscopy and, potentially, reduce clinical errors and provide quantifiable measures for further clinical training.


Assuntos
Competência Clínica/normas , Cistoscopia/educação , Treinamento por Simulação/organização & administração , Urologia/educação , Humanos , Modelos Anatômicos , Impressão Tridimensional , Fatores de Tempo , Urologia/normas
20.
NMR Biomed ; 22(8): 891-7, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19588450

RESUMO

Traditional methods of measuring magnetization in magnetic fluid samples, such as vibrating sample magnetometry (VSM), are typically limited to maximum field strengths of about 1 T. This work demonstrates the ability of MRI to measure the magnetization associated with two commercial MRI contrast agents at 3 T by comparing analytical solutions to experimental imaging results for the field pattern associated with agents in cylindrical vials. The results of the VSM and fitted MRI data match closely. The method represents an improvement over VSM measurements since results are attainable at imaging field strengths. The agents investigated are Feridex, a superparamagnetic iron oxide suspension used primarily for liver imaging, and Magnevist, a paramagnetic, gadolinium-based compound used for tumors, inflammation and vascular lesions. MR imaging of the agents took place in sealed cylindrical vials in the presence of a surrounding volume of deionized water where the effects of the contrast agents had a measurable effect on the water's magnetization in the vicinity of the compartment of contrast agent. A pair of phase images were used to reconstruct a B(0) fieldmap. The resultant B(0) maps in the water region, corrected for shimming and container edge effects, were used to predict the agent's magnetization at 3 T. The results were compared with the results from VSM measurements up to 1.2 T and close correlation was observed. The technique should be of interest to those seeking quantification of the magnetization associated with magnetic suspensions beyond the traditional scope of VSM. The magnetization needs to be sufficiently strong (M(s) >or= 50 Am(2)/kg Fe for Feridex and X(m) >or=5 x 10(-5) m(3)/kg Gd for Magnevist) for a measurable dipole field in the surrounding water. For this reason, the technique is mostly suitable for undiluted agents.


Assuntos
Meios de Contraste/química , Gadolínio/química , Imageamento por Ressonância Magnética/métodos , Dextranos , Óxido Ferroso-Férrico/química , Imageamento por Ressonância Magnética/instrumentação , Magnetismo/métodos , Nanopartículas de Magnetita , Modelos Teóricos
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