Detalhe da pesquisa
1.
A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein.
J Biol Chem
; 300(4): 107163, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38484799
2.
The battle for silver binding: How the interplay between the SilE, SilF, and SilB proteins contributes to the silver efflux pump mechanism.
J Biol Chem
; 299(8): 105004, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37394004
3.
Making 1H-1H Couplings More Accessible and Accurate with Selective 2DJ NMR Experiments Aided by 13C Satellites.
Anal Chem
; 96(18): 7056-7064, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38666447
4.
Development of Receptor for Advanced Glycation End Products (RAGE) ligands through target directed dynamic combinatorial chemistry: a novel class of possible antagonists.
Chemistry
; 30(20): e202303255, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38317623
5.
Conformation and Affinity Modulations by Multiple Phosphorylation Occurring in the BIN1 SH3 Domain Binding Site of the Tau Protein Proline-Rich Region.
Biochemistry
; 62(11): 1631-1642, 2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37167199
6.
Hepatitis E virus RNA-dependent RNA polymerase is involved in RNA replication and infectious particle production.
Hepatology
; 75(1): 170-181, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387882
7.
Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment.
Mol Ther
; 30(4): 1484-1499, 2022 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007758
8.
Identification of a Potential Inhibitor of the FIV p24 Capsid Protein and Characterization of Its Binding Site.
Biochemistry
; 60(24): 1896-1908, 2021 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34096272
9.
NMR Spectroscopy of the Main Protease of SARS-CoV-2 and Fragment-Based Screening Identify Three Protein Hotspots and an Antiviral Fragment.
Angew Chem Int Ed Engl
; 60(48): 25428-25435, 2021 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34570415
10.
Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication.
J Biol Chem
; 294(35): 13171-13185, 2019 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31315928
11.
Identification of the Tau phosphorylation pattern that drives its aggregation.
Proc Natl Acad Sci U S A
; 114(34): 9080-9085, 2017 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28784767
12.
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.
Acta Neuropathol
; 138(4): 631-652, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31065832
13.
NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B.
J Biol Chem
; 292(44): 18024-18043, 2017 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28912275
14.
Interaction study between HCV NS5A-D2 and NS5B using 19F NMR.
J Biomol NMR
; 70(1): 67-76, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29218486
15.
The O-ß-linked N-acetylglucosaminylation of the Lamin B receptor and its impact on DNA binding and phosphorylation.
Biochim Biophys Acta Gen Subj
; 1862(4): 825-835, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29337275
16.
Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A.
Biochemistry
; 56(24): 3029-3048, 2017 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28535337
17.
Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase.
J Biol Chem
; 291(14): 7742-53, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26858248
18.
Characterization of ERM transactivation domain binding to the ACID/PTOV domain of the Mediator subunit MED25.
Nucleic Acids Res
; 43(14): 7110-21, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26130716
19.
Metabolic phenotyping of human plasma by 1 H-NMR at high and medium magnetic field strengths: a case study for lung cancer.
Magn Reson Chem
; 55(8): 706-713, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28061019
20.
A ß-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52.
Biochemistry
; 55(38): 5366-76, 2016 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27641460