Detalhe da pesquisa
1.
Glucosamine activates autophagy in vitro and in vivo.
Arthritis Rheum
; 65(7): 1843-52, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23606170
2.
Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection.
Arthritis Rheum
; 64(4): 1182-92, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22034068
3.
Expression patterns and function of chromatin protein HMGB2 during mesenchymal stem cell differentiation.
J Biol Chem
; 286(48): 41489-41498, 2011 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21890638
4.
Autophagy activation by rapamycin reduces severity of experimental osteoarthritis.
Ann Rheum Dis
; 71(4): 575-81, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22084394
5.
Chromatin protein HMGB2 regulates articular cartilage surface maintenance via beta-catenin pathway.
Proc Natl Acad Sci U S A
; 106(39): 16817-22, 2009 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19805379
6.
Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis.
Proc Natl Acad Sci U S A
; 106(4): 1181-6, 2009 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19139395
7.
Reduced Levels of H2S in Diabetes-Associated Osteoarthritis Are Linked to Hyperglycaemia, Nrf-2/HO-1 Signalling Downregulation and Chondrocyte Dysfunction.
Antioxidants (Basel)
; 11(4)2022 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35453313
8.
Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis.
Arthritis Rheum
; 62(3): 791-801, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20187128
9.
Proteomic analysis by two-dimensional electrophoresis to identify the normal human chondrocyte proteome stimulated by tumor necrosis factor alpha and interleukin-1beta.
Arthritis Rheum
; 62(3): 802-14, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20131227
10.
Flux-Based Assay for the Identification of Autophagy Modulators for Osteoarthritis.
J Vis Exp
; (161)2020 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32716395
11.
Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy.
EBioMedicine
; 45: 588-605, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31285188
12.
Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis.
Front Physiol
; 9: 706, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29988615
13.
Autophagy: a new therapeutic target in cartilage injury and osteoarthritis.
J Am Acad Orthop Surg
; 20(4): 261-2, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22474097
14.
The relationship of autophagy defects to cartilage damage during joint aging in a mouse model.
Arthritis Rheumatol
; 67(6): 1568-76, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25708836
15.
Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes.
Arthritis Rheumatol
; 67(4): 966-76, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605458
16.
FoxO transcription factors support oxidative stress resistance in human chondrocytes.
Arthritis Rheumatol
; 66(12): 3349-58, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25186470
17.
Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA.
Nat Rev Rheumatol
; 7(10): 579-87, 2011 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21808292
18.
Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes.
Arthritis Rheum
; 58(8): 2409-19, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18668543
19.
[Evidence of inflammatory mechanisms in osteoarthritis]. / Evidencia de mecanismos inflamatorios en la osteoartritis.
Reumatol Clin
; 3 Suppl 3: S23-7, 2007 Oct.
Artigo
em Espanhol
| MEDLINE | ID: mdl-21794477
20.
Pig chondrocyte xenoimplants for human chondral defect repair: an in vitro model.
Wound Repair Regen
; 12(4): 444-52, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15260810