Detalhe da pesquisa
1.
Aryl azoles based scaffolds for disrupting tumor microenvironment.
Bioorg Med Chem
; 95: 117490, 2023 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37862936
2.
Synthesis and Biological Evaluation of Potential Oncoimmunomodulator Agents.
Int J Mol Sci
; 24(3)2023 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768935
3.
Exploring BenzylethoxyAryl Urea Scaffolds for Multitarget Immunomodulation Therapies.
Int J Mol Sci
; 24(10)2023 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37239929
4.
Synthesis and Biological Evaluation of Small Molecules as Potential Anticancer Multitarget Agents.
Int J Mol Sci
; 23(13)2022 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806053
5.
Synthesis of Combretastatin A-4 and 3'-Aminocombretastatin A-4 derivatives with Aminoacid Containing Pendants and Study of Their Interaction with Tubulin and as Downregulators of the VEGF, hTERT and c-Myc Gene Expression.
Molecules
; 25(3)2020 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32033084
6.
Arylpyridines, arylpyrimidines and related compounds as potential modulator agents of the VEGF, hTERT and c-Myc oncogenes.
Bioorg Med Chem
; 27(5): 880-887, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30733086
7.
Synthesis and biological evaluation of cyclic derivatives of combretastatin A-4 containing group 14 elements.
Org Biomol Chem
; 16(32): 5859-5870, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30070286
8.
Synthesis, Binding Properties, and Differences in Cell Uptake ofâ G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates.
Chemistry
; 23(9): 2157-2164, 2017 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27925323
9.
One drug for two targets: Biological evaluation of antiretroviral agents endowed with antiproliferative activity.
Bioorg Med Chem Lett
; 27(11): 2502-2505, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408224
10.
Cytotoxic, Antiangiogenic and Antitelomerase Activity of Glucosyl- and Acyl- Resveratrol Prodrugs and Resveratrol Sulfate Metabolites.
Chembiochem
; 17(14): 1343-8, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27147200
11.
Design, synthesis and antimalarial evaluation of novel thiazole derivatives.
Bioorg Med Chem Lett
; 26(16): 3938-44, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27432764
12.
Synthesis and biological evaluation of simplified pironetin analogues with modifications in the side chain and the lactone ring.
Org Biomol Chem
; 15(1): 220-232, 2016 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27901163
13.
Synthesis and evaluation of biphenyl derivatives as potential downregulators of VEGF protein secretion and telomerase-related gene expressions.
Bioorg Med Chem
; 24(14): 3108-15, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27259399
14.
Effects of Curcuminoid Pyrazoles on Cancer Cells and on the Expression of Telomerase Related Genes.
Arch Pharm (Weinheim)
; 349(7): 532-8, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27270752
15.
Inhibitory effect of pironetin analogue/colchicine hybrids on the expression of the VEGF, hTERT and c-Myc genes.
Bioorg Med Chem Lett
; 25(16): 3194-8, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26094121
16.
The Mechanism of the Interactions of Pironetin Analog/Combretastatin A-4 Hybrids with Tubulin.
Arch Pharm (Weinheim)
; 348(8): 541-7, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085125
17.
Synthesis, leishmanicidal and cytotoxic activity of triclosan-chalcone, triclosan-chromone and triclosan-coumarin hybrids.
Molecules
; 19(9): 13251-66, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25170948
18.
Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ring.
Org Biomol Chem
; 11(35): 5809-26, 2013 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23892508
19.
Inhibition of VEGF expression in cancer cells and endothelial cell differentiation by synthetic stilbene derivatives.
Bioorg Med Chem
; 21(11): 3010-5, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23623255
20.
Synthesis of combretastatin A-4 O-alkyl derivatives and evaluation of their cytotoxic, antiangiogenic and antitelomerase activity.
Bioorg Med Chem
; 21(23): 7267-74, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24145138