Detalhe da pesquisa
1.
Structure-activity and structure-property relationship studies of spirocyclic chromanes with antimalarial activity.
Bioorg Med Chem
; 57: 116629, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35091169
2.
Highly N-Methylated Peptides from the Antarctic Sponge Inflatella coelosphaeroides Are Active against Plasmodium falciparum.
J Nat Prod
; 85(10): 2454-2460, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36178104
3.
Artemisinin-resistant Plasmodium falciparum parasites exhibit altered patterns of development in infected erythrocytes.
Antimicrob Agents Chemother
; 59(6): 3156-67, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25779582
4.
Fitness of artemisinin-resistant Plasmodium falciparum in vitro.
J Antimicrob Chemother
; 70(10): 2787-96, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26203183
5.
Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum.
Sci Rep
; 13(1): 399, 2023 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36624300
6.
Chemogenomic Profiling of a Plasmodium falciparum Transposon Mutant Library Reveals Shared Effects of Dihydroartemisinin and Bortezomib on Lipid Metabolism and Exported Proteins.
Microbiol Spectr
; 11(3): e0501422, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37067430
7.
A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in Plasmodium falciparum.
mSphere
; 8(4): e0015223, 2023 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37219373
8.
Synthesis of Mono- and Bisperoxide-Bridged Artemisinin Dimers to Elucidate the Contribution of Dimerization to Antimalarial Activity.
ACS Infect Dis
; 7(7): 2013-2024, 2021 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33792305
9.
Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1H)-Quinolones with Single Dose Cures.
J Med Chem
; 64(10): 6581-6595, 2021 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33979164
10.
The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite.
Nat Commun
; 12(1): 4563, 2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34315897
11.
Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure-Activity and Structure-Property Relationship Studies.
J Med Chem
; 61(4): 1450-1473, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29215279
12.
ICI 56,780 Optimization: Structure-Activity Relationship Studies of 7-(2-Phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity.
J Med Chem
; 59(14): 6943-60, 2016 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27291102