Detalhe da pesquisa
1.
A pRb-responsive, RGD-modified, and hyaluronidase-armed canine oncolytic adenovirus for application in veterinary oncology.
Mol Ther
; 22(5): 986-98, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24448161
2.
Adenovirus i-leader truncation bioselected against cancer-associated fibroblasts to overcome tumor stromal barriers.
Mol Ther
; 20(1): 54-62, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21863000
3.
Phase I, multicenter, open-label study of intravenous VCN-01 oncolytic adenovirus with or without nab-paclitaxel plus gemcitabine in patients with advanced solid tumors.
J Immunother Cancer
; 10(3)2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35338084
4.
Hyaluronidase expression by an oncolytic adenovirus enhances its intratumoral spread and suppresses tumor growth.
Mol Ther
; 18(7): 1275-83, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20442708
5.
Verapamil enhances the antitumoral efficacy of oncolytic adenoviruses.
Mol Ther
; 18(5): 903-11, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20179683
6.
Minimal RB-responsive E1A promoter modification to attain potency, selectivity, and transgene-arming capacity in oncolytic adenoviruses.
Mol Ther
; 18(11): 1960-71, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20808288
7.
Oncolytic adenovirus with hyaluronidase activity that evades neutralizing antibodies: VCN-11.
J Control Release
; 332: 517-528, 2021 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675877
8.
VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects.
J Immunother Cancer
; 9(11)2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35149591
9.
ICOVIR-5 shows E2F1 addiction and potent antiglioma effect in vivo.
Cancer Res
; 67(17): 8255-63, 2007 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17804740
10.
The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models.
Sci Rep
; 9(1): 14368, 2019 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591461
11.
A Phase 1 Trial of Oncolytic Adenovirus ICOVIR-5 Administered Intravenously to Cutaneous and Uveal Melanoma Patients.
Hum Gene Ther
; 30(3): 352-364, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30234393
12.
Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01.
Sci Transl Med
; 11(476)2019 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30674657
13.
Deletion of VAI and VAII RNA genes in the design of oncolytic adenoviruses.
Hum Gene Ther
; 17(9): 929-40, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16972761
14.
Ras-dependent oncolysis with an adenovirus VAI mutant.
Cancer Res
; 63(17): 5544-50, 2003 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14500393
15.
Correction: Characterization of the Antiglioma Effect of the Oncolytic Adenovirus VCN-01.
PLoS One
; 11(6): e0157619, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27280773
16.
Characterization of the Antiglioma Effect of the Oncolytic Adenovirus VCN-01.
PLoS One
; 11(1): e0147211, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26808201
17.
The Oncolytic Adenovirus VCN-01 as Therapeutic Approach Against Pediatric Osteosarcoma.
Clin Cancer Res
; 22(9): 2217-25, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26603261
18.
Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression.
Clin Cancer Res
; 21(6): 1406-18, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25391696
19.
Adenovirus-mediated gene transfer to tumor cells.
Methods Mol Biol
; 246: 121-38, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-14970588
20.
Adeno-associated virus enhances wild-type and oncolytic adenovirus spread.
Hum Gene Ther Methods
; 24(6): 372-80, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24020980