Detalhe da pesquisa
1.
The genomic landscape of response to EGFR blockade in colorectal cancer.
Nature
; 526(7572): 263-7, 2015 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26416732
2.
Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer.
Gut
; 67(11): 1995-2005, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28982739
3.
Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial.
Lancet Oncol
; 17(6): 738-746, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27108243
4.
Impaired seroconversion after SARS-CoV-2 mRNA vaccines in patients with solid tumours receiving anticancer treatment.
Eur J Cancer
; 163: 16-25, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35032813
5.
Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients.
Cancer Discov
; 12(7): 1656-1675, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35522273
6.
Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ.
Nat Commun
; 12(1): 2340, 2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33879786
7.
A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin.
Clin Cancer Res
; 26(6): 1372-1384, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31831554
8.
Long-term Clinical Outcome of Trastuzumab and Lapatinib for HER2-positive Metastatic Colorectal Cancer.
Clin Colorectal Cancer
; 19(4): 256-262.e2, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32919890
9.
Whole exome sequencing analysis of urine trans-renal tumour DNA in metastatic colorectal cancer patients.
ESMO Open
; 4(6)2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32149725
10.
Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer.
Clin Cancer Res
; 25(20): 6243-6259, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31375513
11.
Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer.
Cancer Cell
; 34(1): 148-162.e7, 2018 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29990497
12.
Digital PCR assessment of MGMT promoter methylation coupled with reduced protein expression optimises prediction of response to alkylating agents in metastatic colorectal cancer patients.
Eur J Cancer
; 71: 43-50, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27997874
13.
Pooled Analysis of Clinical Outcome of Patients with Chemorefractory Metastatic Colorectal Cancer Treated within Phase I/II Clinical Studies Based on Individual Biomarkers of Susceptibility: A Single-Institution Experience.
Target Oncol
; 12(4): 525-533, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28669023
14.
Mutation-Enrichment Next-Generation Sequencing for Quantitative Detection of KRAS Mutations in Urine Cell-Free DNA from Patients with Advanced Cancers.
Clin Cancer Res
; 23(14): 3657-3666, 2017 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096270
15.
Empowering Clinical Decision Making in Oligometastatic Colorectal Cancer: The Potential Role of Drug Screening of Patient-Derived Organoids.
JCO Precis Oncol
; 52021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34327296
16.
Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer.
Cancer Res
; 76(15): 4504-15, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27312529
17.
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
Nat Med
; 21(7): 795-801, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26030179
18.
Epigenetic inactivation of the BRCA1 interactor SRBC and resistance to oxaliplatin in colorectal cancer.
J Natl Cancer Inst
; 106(1): djt322, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24273214
19.
Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer.
Clin Cancer Res
; 19(8): 2265-72, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23422094
20.
Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer.
Cancer Discov
; 3(6): 658-73, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23729478