Detalhe da pesquisa
1.
Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3.
J Biol Chem
; 299(4): 104584, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36889588
2.
PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells.
J Biol Chem
; 298(8): 102175, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35752367
3.
Bladder Cancer Invasion Is Mediated by Mammalian Target of Rapamycin Complex 2-Driven Regulation of Nitric Oxide and Invadopodia Formation.
Am J Pathol
; 191(12): 2203-2218, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34428425
4.
A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP.
J Biol Chem
; 295(30): 10394-10405, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32506052
5.
Correction to: Crystal structure of PKG Iß holoenzyme reveals a transinhibiting dimer assembly.
J Transl Med
; 18(1): 27, 2020 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31948450
6.
Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46.
J Biol Chem
; 293(28): 10985-10992, 2018 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29769318
7.
Phosphorylation of protein kinase A (PKA) regulatory subunit RIα by protein kinase G (PKG) primes PKA for catalytic activity in cells.
J Biol Chem
; 293(12): 4411-4421, 2018 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378851
8.
The activity of cGMP-dependent protein kinase Iα is not directly regulated by oxidation-induced disulfide formation at cysteine 43.
J Biol Chem
; 292(20): 8262-8268, 2017 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28360102
9.
Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase-Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase.
Am J Pathol
; 187(1): 200-213, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27979310
10.
O-GlcNAcylation of 8-Oxoguanine DNA Glycosylase (Ogg1) Impairs Oxidative Mitochondrial DNA Lesion Repair in Diabetic Hearts.
J Biol Chem
; 291(51): 26515-26528, 2016 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27816939
11.
Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II.
J Biol Chem
; 291(11): 5623-5633, 2016 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26769964
12.
Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections.
Am J Hum Genet
; 93(2): 398-404, 2013 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23910461
13.
Structures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability.
Biochemistry
; 54(29): 4419-22, 2015 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26132214
14.
Crystal structure of the cGMP-dependent protein kinase II leucine zipper and Rab11b protein complex reveals molecular details of G-kinase-specific interactions.
J Biol Chem
; 289(37): 25393-403, 2014 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25070890
15.
Letter by Casteel Regarding Article, "Blood Pressure-Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of the cGMP-Dependent Protein Kinase".
Circulation
; 140(22): e808-e809, 2019 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31765253
16.
cGMP-dependent protein kinase Iß regulates breast cancer cell migration and invasion via interaction with the actin/myosin-associated protein caldesmon.
J Cell Sci
; 126(Pt 7): 1626-36, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23418348
17.
Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate.
Biochem J
; 454(1): 91-9, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23734909
18.
A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells.
Sci Signal
; 17(821): eadi7861, 2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38289986
19.
The Antioxidant/Nitric Oxide-Quenching Agent Cobinamide Prevents Aortic Disease in a Mouse Model of Marfan Syndrome.
JACC Basic Transl Sci
; 9(1): 46-62, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38362350
20.
Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration.
J Biol Chem
; 287(45): 38367-78, 2012 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22992742