Detalhe da pesquisa
1.
Automated Generation of hiPSC-Derived Hepatic Progeny by Cost-Efficient Compounds.
Stem Cells
; 41(11): 1076-1088, 2023 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37616601
2.
Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders.
Altern Lab Anim
; 52(2): 117-131, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38235727
3.
Exploring Individual Variability in Drug-Induced Liver Injury (DILI) Responses through Metabolomic Analysis.
Int J Mol Sci
; 25(5)2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38474249
4.
Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and Consistency with Current Adverse Outcome Pathways.
Int J Mol Sci
; 25(10)2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38791241
5.
Enhancing the accuracy of mid-infrared spectroscopy-based liver steatosis quantification using digital image analysis as a reference.
Analyst
; 148(13): 3097-3106, 2023 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37313751
6.
Comparing the direct assessment of steatosis in liver explants with mid- and near-infrared vibrational spectroscopy, prior to organ transplantation.
Analyst
; 148(17): 3986-3991, 2023 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37539806
7.
Metabolomics-based strategy to assess drug hepatotoxicity and uncover the mechanisms of hepatotoxicity involved.
Arch Toxicol
; 97(6): 1723-1738, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37022445
8.
A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes.
J Proteome Res
; 21(3): 702-712, 2022 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34982937
9.
Quantitative Prediction of Steatosis in Patients with Non-Alcoholic Fatty Liver by Means of Hepatic MicroRNAs Present in Serum and Correlating with Hepatic Fat.
Int J Mol Sci
; 23(16)2022 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36012565
10.
Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes.
Arch Toxicol
; 95(9): 3049-3062, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34274980
11.
The in vitro assessment of the toxicity of volatile, oxidisable, redox-cycling compounds: phenols as an example.
Arch Toxicol
; 95(6): 2109-2121, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34032869
12.
Comparing in vitro human liver models to in vivo human liver using RNA-Seq.
Arch Toxicol
; 95(2): 573-589, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106934
13.
Toward Rapid Screening of Liver Grafts at the Operating Room Using Mid-infrared Spectroscopy.
Anal Chem
; 92(21): 14542-14549, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33084322
14.
Improved in vivo efficacy of clinical-grade cryopreserved human hepatocytes in mice with acute liver failure.
Cytotherapy
; 22(2): 114-121, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31987755
15.
Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes.
Arch Toxicol
; 94(2): 589-607, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31894354
16.
Angiopoietin-Like Protein 8 Is a Novel Vitamin D Receptor Target Gene Involved in Nonalcoholic Fatty Liver Pathogenesis.
Am J Pathol
; 188(12): 2800-2810, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30248338
17.
Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes.
Arch Toxicol
; 93(2): 519-532, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30426164
18.
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
Arch Toxicol
; 93(6): 1609-1637, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31250071
19.
Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury.
Arch Toxicol
; 92(1): 383-399, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28762043
20.
Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes.
Arch Toxicol
; 92(12): 3505-3515, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30317417