Detalhe da pesquisa
1.
DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C.
Mol Cell
; 83(20): 3659-3668.e10, 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37832547
2.
Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.
Nature
; 621(7978): 415-422, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37674080
3.
The Fanconi anaemia pathway: new players and new functions.
Nat Rev Mol Cell Biol
; 17(6): 337-49, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27145721
4.
CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress.
Mol Cell
; 72(3): 568-582.e6, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30344097
5.
Publisher Correction: Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.
Nature
; 626(7999): E13, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38273133
6.
A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells.
Nucleic Acids Res
; 51(15): 7988-8004, 2023 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37395445
7.
Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis.
Mol Cell
; 54(1): 107-118, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24657165
8.
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Nature
; 518(7538): 258-62, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25642963
9.
Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions.
Blood
; 117(15): e161-70, 2011 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21325596
10.
A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors.
Nat Cancer
; 2(6): 598-610, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34179826
11.
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation.
Nat Cell Biol
; 19(11): 1371-1378, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29035360
12.
Repair Pathway Choices and Consequences at the Double-Strand Break.
Trends Cell Biol
; 26(1): 52-64, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26437586
13.
FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair.
Cell Rep
; 15(11): 2488-99, 2016 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27264184
14.
Biallelic inactivation of REV7 is associated with Fanconi anemia.
J Clin Invest
; 126(9): 3580-4, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27500492
15.
Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer.
Cancer Discov
; 5(11): 1137-54, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26463832
16.
A unique subset of epithelial ovarian cancers with platinum sensitivity and PARP inhibitor resistance.
Cancer Res
; 75(4): 628-34, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25634215
17.
A prospective study of bone marrow hematopoietic and mesenchymal stem cells in type 1 Gaucher disease patients.
PLoS One
; 8(7): e69293, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935976
18.
Gene polymorphisms and cytokine plasma levels as predictive factors of complications after cardiopulmonary bypass.
J Thorac Cardiovasc Surg
; 144(2): 467-73, 473.e1-2, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22264418
19.
Biallelic inactivation of REV7 is associated with Fanconi anemia.
J Clin Invest
; 127(3): 1117, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28248207
20.
Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.
Cell Stem Cell
; 11(1): 36-49, 2012 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22683204