Detalhe da pesquisa
1.
Insulin-regulated aminopeptidase inhibitor-mediated increases in dendritic spine density are facilitated by glucose uptake.
J Neurochem
; 153(4): 485-494, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31556456
2.
Insulin-regulated aminopeptidase deficiency impairs cardiovascular adaptations and placental development during pregnancy.
Clin Sci (Lond)
; 134(23): 3213-3228, 2020 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33252660
3.
Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures.
J Neurosci
; 35(34): 11960-75, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26311777
4.
Binding to and Inhibition of Insulin-Regulated Aminopeptidase by Macrocyclic Disulfides Enhances Spine Density.
Mol Pharmacol
; 89(4): 413-24, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26769413
5.
Forebrain neurone-specific deletion of insulin-regulated aminopeptidase causes age related deficits in memory.
Neurobiol Learn Mem
; 136: 174-182, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27713012
6.
Antidepressant-like effects of oxytocin in mice are dependent on the presence of insulin-regulated aminopeptidase.
Int J Neuropsychopharmacol
; 16(5): 1153-63, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23177092
7.
Development of a sandwich ELISA to detect circulating, soluble IRAP as a potential disease biomarker.
Sci Rep
; 13(1): 17565, 2023 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38001104
8.
Inhibition of insulin-regulated aminopeptidase confers neuroprotection in a conscious model of ischemic stroke.
Sci Rep
; 13(1): 19722, 2023 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37957163
9.
Age-related reduction in brain ACE-2 is not exacerbated by Alzheimer's disease pathology in mouse models of Alzheimer's disease.
Aging Brain
; 3: 100062, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36911263
10.
Different cross-presentation pathways in steady-state and inflammatory dendritic cells.
Proc Natl Acad Sci U S A
; 106(48): 20377-81, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19918052
11.
Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.
Biochemistry
; 50(13): 2611-22, 2011 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21348480
12.
Transcriptional signature in microglia associated with Aß plaque phagocytosis.
Nat Commun
; 12(1): 3015, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34021136
13.
Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase.
Mol Pharmacol
; 78(4): 600-7, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20628006
14.
Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory.
Neurobiol Learn Mem
; 93(1): 19-30, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19660563
15.
Is There an Interplay Between the Functional Domains of IRAP?
Front Cell Dev Biol
; 8: 585237, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33134302
16.
Insulin-Regulated Aminopeptidase Inhibition Ameliorates Metabolism in Obese Zucker Rats.
Front Mol Biosci
; 7: 586225, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33344504
17.
Macrocyclic peptidomimetics as inhibitors of insulin-regulated aminopeptidase (IRAP).
RSC Med Chem
; 11(2): 234-244, 2020 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33479630
18.
Angiotensin IV and LVV-haemorphin 7 enhance spatial working memory in rats: effects on hippocampal glucose levels and blood flow.
Neurobiol Learn Mem
; 92(1): 19-26, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19233301
19.
Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase.
FASEB J
; 22(12): 4209-17, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18716029
20.
Social behaviour is altered in the insulin-regulated aminopeptidase knockout mouse.
Behav Brain Res
; 376: 112150, 2019 12 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31419522