Detalhe da pesquisa
1.
A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis.
Methods
; 203: 297-310, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34500068
2.
TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation.
J Biol Chem
; 295(12): 3808-3825, 2020 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029478
3.
LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation.
EMBO Rep
; 16(1): 79-86, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25427558
4.
Rab35: GEFs, GAPs and effectors.
Traffic
; 14(11): 1109-17, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23905989
5.
Interplay between Rab35 and Arf6 controls cargo recycling to coordinate cell adhesion and migration.
J Cell Sci
; 126(Pt 3): 722-31, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23264734
6.
Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons.
iScience
; 27(3): 109166, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38433895
7.
An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids.
Cells
; 12(4)2023 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36831212
8.
Role of TI-VAMP and CD82 in EGFR cell-surface dynamics and signaling.
J Cell Sci
; 123(Pt 5): 723-35, 2010 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20144992
9.
Rapid Generation of Ventral Spinal Cord-like Astrocytes from Human iPSCs for Modeling Non-Cell Autonomous Mechanisms of Lower Motor Neuron Disease.
Cells
; 11(3)2022 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35159209
10.
Target 2035 - update on the quest for a probe for every protein.
RSC Med Chem
; 13(1): 13-21, 2022 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35211674
11.
An Arf/Rab cascade controls the growth and invasiveness of glioblastoma.
J Cell Biol
; 220(2)2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33443570
12.
Dynamic interaction of amphiphysin with N-WASP regulates actin assembly.
J Biol Chem
; 284(49): 34244-56, 2009 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19759398
13.
The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALS.
Front Cell Neurosci
; 14: 594975, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33281562
14.
Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery.
Neurosci Lett
; 731: 135028, 2020 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32380146
15.
Open Science Meets Stem Cells: A New Drug Discovery Approach for Neurodegenerative Disorders.
Front Neurosci
; 12: 47, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467610
16.
DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.
J Cell Biol
; 208(5): 629-48, 2015 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25713415
17.
Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking.
FEBS Lett
; 583(23): 3817-26, 2009 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19837067
18.
Role of HRB in clathrin-dependent endocytosis.
J Biol Chem
; 283(49): 34365-73, 2008 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18819912