Detalhe da pesquisa
1.
A conserved arginine in NS5 binds genomic 3' stem-loop RNA for primer-independent initiation of flavivirus RNA replication.
RNA
; 28(2): 177-193, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34759006
2.
Mutations in the cytoplasmic domain of dengue virus NS4A affect virus fitness and interactions with other non-structural proteins.
J Gen Virol
; 101(9): 941-953, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589122
3.
Dengue Virus and Zika Virus Serological Cross-reactivity and Their Impact on Pathogenesis in Mice.
J Infect Dis
; 219(2): 223-233, 2019 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30085051
4.
Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis.
J Virol
; 92(7)2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321322
5.
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication.
PLoS Pathog
; 11(3): e1004682, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25775415
6.
Dengue Virus Infection with Highly Neutralizing Levels of Cross-Reactive Antibodies Causes Acute Lethal Small Intestinal Pathology without a High Level of Viremia in Mice.
J Virol
; 89(11): 5847-61, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25787279
7.
Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication.
J Virol
; 89(20): 10717-21, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26269182
8.
Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein.
Elife
; 122024 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38787378
9.
Serotype-Specific Regulation of Dengue Virus NS5 Protein Subcellular Localization.
ACS Infect Dis
; 2024 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38811007
10.
Tissue-specific expansion of Zika virus isogenic variants drive disease pathogenesis.
EBioMedicine
; 91: 104570, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37068347
11.
Therapeutics for flaviviral infections.
Antiviral Res
; 210: 105517, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36592668
12.
Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes.
Eur J Med Chem
; 252: 115283, 2023 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36965228
13.
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation.
Virology
; 583: 1-13, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37060797
14.
Experimental evidence for a high rate of maternal-fetal transmission of dengue virus in the presence of antibodies in immunocompromised mice.
EBioMedicine
; 77: 103930, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35290828
15.
Optimal flexibility of the linker region of Zika virus NS5 methyltransferase-polymerase is critical for virus replication.
Antiviral Res
; 195: 105194, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699863
16.
Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease.
Eur J Med Chem
; 224: 113695, 2021 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298282
17.
18F-fluorodeoxyglucose positron emission tomography as a window into human dengue pathophysiology.
Antiviral Res
; 185: 104991, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33279522
18.
Zika virus nonstructural protein 5 residue R681 is critical for dimer formation and enzymatic activity.
FEBS Lett
; 593(12): 1272-1291, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31090058
19.
Assessing the utility of antivirals for preventing maternal-fetal transmission of zika virus in pregnant mice.
Antiviral Res
; 167: 104-109, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31051186
20.
The Potential Role of the ZIKV NS5 Nuclear Spherical-Shell Structures in Cell Type-Specific Host Immune Modulation during ZIKV Infection.
Cells
; 8(12)2019 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31779251