Detalhe da pesquisa
1.
CNS macrophages differentially rely on an intronic Csf1r enhancer for their development.
Development
; 147(23)2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33323375
2.
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis.
Neuropathol Appl Neurobiol
; 49(1): e12851, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36181265
3.
Quantitative T1 brain mapping in early relapsing-remitting multiple sclerosis: longitudinal changes, lesion heterogeneity and disability.
Eur Radiol
; 2023 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37943312
4.
NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis.
J Pathol
; 256(3): 262-268, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34883532
5.
Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72-ALS.
J Pathol
; 258(4): 366-381, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36070099
6.
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Alzheimers Dement
; 19(4): 1245-1259, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993441
7.
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.
Acta Neuropathol
; 144(3): 465-488, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895140
8.
PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD.
Acta Neuropathol
; 144(5): 939-966, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36121477
9.
Rim lesions are demonstrated in early relapsing-remitting multiple sclerosis using 3 T-based susceptibility-weighted imaging in a multi-institutional setting.
Neuroradiology
; 64(1): 109-117, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34664112
10.
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis.
Acta Neuropathol
; 141(2): 257-279, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398403
11.
Prevalence of multimorbidity and its impact on survival in people with motor neuron disease.
Eur J Neurol
; 28(8): 2756-2765, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34036680
12.
Dysregulation of AMPA receptor subunit expression in sporadic ALS post-mortem brain.
J Pathol
; 250(1): 67-78, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31579943
13.
Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology.
Glia
; 68(5): 1046-1064, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31841614
14.
Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis.
Acta Neuropathol
; 140(2): 143-167, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32572598
15.
Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS.
J Neurol Neurosurg Psychiatry
; 91(2): 149-157, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515300
16.
Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND.
J Neurol Neurosurg Psychiatry
; 91(3): 245-253, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31871139
17.
Interleukin-8 dysregulation is implicated in brain dysmaturation following preterm birth.
Brain Behav Immun
; 90: 311-318, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32920182
18.
Reversal of proliferation deficits caused by chromosome 16p13.11 microduplication through targeting NFκB signaling: an integrated study of patient-derived neuronal precursor cells, cerebral organoids and in vivo brain imaging.
Mol Psychiatry
; 24(2): 294-311, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30401811
19.
Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction.
Mol Psychiatry
; 24(11): 1641-1654, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31481758
20.
The Dementias Platform UK (DPUK) Data Portal.
Eur J Epidemiol
; 35(6): 601-611, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32328990