Detalhe da pesquisa
1.
Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction.
Proc Natl Acad Sci U S A
; 117(46): 29101-29112, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33127758
2.
FUS-mediated dysregulation of Sema5a, an autism-related gene, in FUS mice with hippocampus-dependent cognitive deficits.
Hum Mol Genet
; 28(22): 3777-3791, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31509188
3.
FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons.
iScience
; 26(11): 108152, 2023 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37920668
4.
Receptor guanylyl cyclases in Inka cells targeted by eclosion hormone.
Proc Natl Acad Sci U S A
; 106(32): 13371-6, 2009 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19666575
5.
Cholesterol dyshomeostasis in amyotrophic lateral sclerosis: cause, consequence, or epiphenomenon?
FEBS J
; 289(24): 7688-7709, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34469619
6.
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
J Cell Biol
; 220(9)2021 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34347016
7.
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy.
Autophagy
; 15(5): 827-842, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30669939
8.
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.
Elife
; 82019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30747709
9.
Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects.
PLoS One
; 12(7): e0180828, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28686708
10.
Motor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS.
Brain Res
; 1584: 39-51, 2014 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24275199
11.
Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of Drosophila.
G3 (Bethesda)
; 2(7): 789-802, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22870402