Detalhe da pesquisa
1.
Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells.
Proc Natl Acad Sci U S A
; 119(18): e2201646119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35507892
2.
Exposure and health risk assessment of volatile organic compounds among drivers and passengers in long-distance buses.
Environ Res
; 252(Pt 3): 118959, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38663669
3.
Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity.
Int J Mol Sci
; 24(6)2023 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982602
4.
ACAT1/SOAT1 Blockade Suppresses LPS-Mediated Neuroinflammation by Modulating the Fate of Toll-like Receptor 4 in Microglia.
Int J Mol Sci
; 24(6)2023 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982689
5.
Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer's Disease Mice.
Int J Mol Sci
; 24(13)2023 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446191
6.
Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.
Nature
; 531(7596): 651-5, 2016 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26982734
7.
Exposure and health risk assessment of indoor volatile organic compounds in a medical university.
Environ Res
; 213: 113644, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35697085
8.
Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions.
J Biol Chem
; 294(43): 15836-15849, 2019 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31495784
9.
Nanodisc scaffold peptide (NSPr) replaces detergent by reconstituting acyl-CoA:cholesterol acyltransferase 1 into peptidiscs.
Arch Biochem Biophys
; 691: 108518, 2020 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32735863
10.
Genetic variants in the circadian rhythm pathway as indicators of prostate cancer progression.
Cancer Cell Int
; 19: 87, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30996687
11.
Triton X-100 or octyl glucoside inactivates acyl-CoA:cholesterol acyltransferase 1 by dissociating it from a two-fold dimer to a two-fold monomer.
Arch Biochem Biophys
; 671: 103-110, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31251920
12.
A common regulatory variant in SLC35B4 influences the recurrence and survival of prostate cancer.
J Cell Mol Med
; 22(7): 3661-3670, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29682886
13.
Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity.
Am J Physiol Endocrinol Metab
; 315(3): E340-E356, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29533741
14.
Cellular cholesterol homeostasis and Alzheimer's disease.
J Lipid Res
; 58(12): 2239-2254, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28298292
15.
Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.
J Biol Chem
; 291(12): 6232-44, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26801614
16.
ABCA1-dependent sterol release: sterol molecule specificity and potential membrane domain for HDL biogenesis.
J Lipid Res
; 57(1): 77-88, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26497474
17.
Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum.
J Biol Chem
; 290(39): 23464-77, 2015 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26198636
18.
Occupational Noise Frequencies and the Incidence of Hypertension in a Retrospective Cohort Study.
Am J Epidemiol
; 184(2): 120-8, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27370792
19.
Correction: Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.
Biochem J
; 477(24): 4811, 2020 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33367592
20.
Inherited Variants in Wnt Pathway Genes Influence Outcomes of Prostate Cancer Patients Receiving Androgen Deprivation Therapy.
Int J Mol Sci
; 17(12)2016 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27898031