Detalhe da pesquisa
1.
Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost.
J Transl Med
; 20(1): 2, 2022 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34980174
2.
An informatics consult approach for generating clinical evidence for treatment decisions.
BMC Med Inform Decis Mak
; 21(1): 281, 2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34641870
3.
An integrative pan-cancer investigation reveals common genetic and transcriptional alterations of AMPK pathway genes as important predictors of clinical outcomes across major cancer types.
BMC Cancer
; 20(1): 773, 2020 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32807122
4.
Aberrations in Notch-Hedgehog signalling reveal cancer stem cells harbouring conserved oncogenic properties associated with hypoxia and immunoevasion.
Br J Cancer
; 121(8): 666-678, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31523055
5.
An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK-STAT signaling components.
Mol Med
; 25(1): 46, 2019 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31684858
6.
Timing gone awry: distinct tumour suppressive and oncogenic roles of the circadian clock and crosstalk with hypoxia signalling in diverse malignancies.
J Transl Med
; 17(1): 132, 2019 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31014368
7.
A novel signature derived from immunoregulatory and hypoxia genes predicts prognosis in liver and five other cancers.
J Transl Med
; 17(1): 14, 2019 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30626396
8.
Mixed evolutionary origins of endogenous biomass-depolymerizing enzymes in animals.
BMC Genomics
; 19(1): 483, 2018 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925310
9.
Pan-cancer analyses of the associations between 109 pre-existing conditions and cancer treatment patterns across 19 adult cancers.
Sci Rep
; 14(1): 464, 2024 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38172343
10.
Cumulative burden of 144 conditions, critical care hospitalisation and premature mortality across 26 adult cancers.
Nat Commun
; 14(1): 1484, 2023 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36932095
11.
Injury primes mutation-bearing astrocytes for dedifferentiation in later life.
Curr Biol
; 33(6): 1082-1098.e8, 2023 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36841240
12.
Cumulative burden of psychiatric disorders and self-harm across 26 adult cancers.
Nat Med
; 28(4): 860-870, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35347280
13.
Multimorbidity patterns and risk of hospitalisation in children: A population cohort study of 3.6 million children in England, with illustrative examples from childhood cancer survivors.
Lancet Reg Health Eur
; 20: 100433, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35799614
14.
Late effects of cancer in children, teenagers and young adults: Population-based study on the burden of 183 conditions, in-patient and critical care admissions and years of life lost.
Lancet Reg Health Eur
; 12: 100248, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34950917
15.
Comparing clinical trial population representativeness to real-world populations: an external validity analysis encompassing 43â895 trials and 5â685â738 individuals across 989 unique drugs and 286 conditions in England.
Lancet Healthy Longev
; 3(10): e674-e689, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36150402
16.
Depression, anxiety, substance misuse and self-harm in children and young people with rare chronic liver disease.
BJPsych Open
; 8(5): e146, 2022 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35900005
17.
Application of ensemble clustering and survival tree analysis for identifying prognostic clinicogenomic features in patients with colorectal cancer from the 100,000 Genomes Project.
BMC Res Notes
; 14(1): 385, 2021 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34600575
18.
Antithrombotic therapy in patients with liver disease: population-based insights on variations in prescribing trends, adherence, persistence and impact on stroke and bleeding.
Lancet Reg Health Eur
; 10: 100222, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34806071
19.
The hypoxic tumour microenvironment: A safe haven for immunosuppressive cells and a therapeutic barrier to overcome.
Cancer Lett
; 487: 34-44, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32470490
20.
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.
BMJ Open
; 10(11): e043828, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33203640