Detalhe da pesquisa
1.
Capillary electrokinetic chromatography for chiral separation of potential SARS-CoV-2 3CL protease inhibitors.
Electrophoresis
; 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38225719
2.
Electrophoretic separation of multiple chiral center analyte with a three cyclodextrins mixture.
Electrophoresis
; 42(17-18): 1810-1817, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33644914
3.
Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry.
Molecules
; 26(19)2021 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34641626
4.
NMR Spectroscopy of the Main Protease of SARS-CoV-2 and Fragment-Based Screening Identify Three Protein Hotspots and an Antiviral Fragment.
Angew Chem Int Ed Engl
; 60(48): 25428-25435, 2021 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34570415
5.
Single and dual cyclodextrins systems for the enantiomeric and diastereoisomeric separations of structurally related dihydropyridone analogues.
Electrophoresis
; 38(15): 1922-1931, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28432793
6.
Characterization of monoclonal antibodies by a fast and easy liquid chromatography-mass spectrometry time-of-flight analysis on culture supernatant.
Anal Biochem
; 491: 52-4, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26302360
7.
Development of HPLC/fluorescence detection method for chiral resolution of dansylated benzimidazoles derivatives.
Biomed Chromatogr
; 28(1): 4-9, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873415
8.
Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses.
Eur J Med Chem
; 250: 115186, 2023 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36796300
9.
Discovery, Structure-Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5.
J Med Chem
; 66(17): 11732-11760, 2023 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37639383
10.
Identification of indole-based activators of insulin degrading enzyme.
Eur J Med Chem
; 228: 113982, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34815130
11.
Supercritical fluid chromatography and liquid chromatography for isomeric separation of a multiple chiral centers analyte.
J Chromatogr A
; 1651: 462270, 2021 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34087720
12.
Farnesoid X Receptor Activation in Brain Alters Brown Adipose Tissue Function via the Sympathetic System.
Front Mol Neurosci
; 14: 808603, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35058750
13.
Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure-Properties Relationships of mPEGylated Small Agonists of TGR5 Receptor.
J Med Chem
; 64(3): 1593-1610, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33470812
14.
Hypothalamic bile acid-TGR5 signaling protects from obesity.
Cell Metab
; 33(7): 1483-1492.e10, 2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33887197
15.
Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.
Bioorg Med Chem Lett
; 19(2): 489-92, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19058965
16.
Enantioseparation of chiral benzimidazole derivatives by electrokinetic chromatography using sulfated cyclodextrins.
J Sep Sci
; 32(11): 1907-15, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19479770
17.
Application of tandem coupling of columns in supercritical fluid chromatography for stereoisomeric separation: Optimization and simulation.
J Chromatogr A
; 1588: 115-126, 2019 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30595432
18.
Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening.
Eur J Med Chem
; 179: 557-566, 2019 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276900
19.
Alkylsquarates as key intermediates for the rapid preparation of original drug-inspired compounds.
Comb Chem High Throughput Screen
; 11(4): 294-303, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18473739
20.
Synthesis of a 200-member library of squaric acid N-hydroxylamide amides.
Bioorg Med Chem Lett
; 18(18): 4968-71, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18760922