Detalhe da pesquisa
1.
Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function.
Immunity
; 51(6): 1074-1087.e9, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31784108
2.
A phase 1 study of pegylated recombinant arginase (PEG-BCT-100) in combination with systemic chemotherapy (capecitabine and oxaliplatin)[PACOX] in advanced hepatocellular carcinoma patients.
Invest New Drugs
; 40(2): 314-321, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34735674
3.
Safety, PK/PD and preliminary anti-tumor activities of pegylated recombinant human arginase 1 (BCT-100) in patients with advanced arginine auxotrophic tumors.
Invest New Drugs
; 39(6): 1633-1640, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34287772
4.
A phase II clinical study on the efficacy and predictive biomarker of pegylated recombinant arginase on hepatocellular carcinoma.
Invest New Drugs
; 39(5): 1375-1382, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33856599
5.
Preliminary efficacy, safety, pharmacokinetics, pharmacodynamics and quality of life study of pegylated recombinant human arginase 1 in patients with advanced hepatocellular carcinoma.
Invest New Drugs
; 33(2): 496-504, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25666409
6.
Systemic Administration of Pegylated Arginase-1 Attenuates the Progression of Diabetic Retinopathy.
Cells
; 11(18)2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36139465
7.
L-Arginine Depletion Improves Spinal Cord Injury via Immunomodulation and Nitric Oxide Reduction.
Biomedicines
; 10(2)2022 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35203413
8.
Macrophage-Derived IL1ß and TNFα Regulate Arginine Metabolism in Neuroblastoma.
Cancer Res
; 79(3): 611-624, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30545920
9.
Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.
Sci Rep
; 8(1): 12096, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30108309
10.
Small cell lung cancer with an epidermal growth factor receptor mutation in primary gefitinib-resistant adenocarcinoma of the lung.
Acta Oncol
; 51(4): 557-9, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22129360
11.
Anti-tumor efficacy of a recombinant human arginase in human hepatocellular carcinoma.
Curr Cancer Drug Targets
; 12(9): 1233-43, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22873218
12.
Recombinant human arginase inhibits the in vitro and in vivo proliferation of human melanoma by inducing cell cycle arrest and apoptosis.
Pigment Cell Melanoma Res
; 24(2): 366-76, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21029397
13.
Synchronous primary lung cancer and epidermal growth factor receptor mutation.
Ann Thorac Surg
; 90(3): e38-9, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20732474