1.
Antibiot Khimioter
; 48(10): 3-6, 2003.
Artigo
em Russo
| MEDLINE
| ID: mdl-15004972
RESUMO
New nutrient media for cultivation of the tobramycin-producing organism were developed. As an additional source of nitrogen the media contain fermentative hydrolysate of the mycelial waste of manufacture of aminoglycoside antibiotics (tobramycin and apramycin). The use of the media provided a 20 to 50% decrease of consumption of soybean meal, an essential food raw material, and design of a low-waste technology for biosynthesis of tobramycin.