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1.
Retina ; 43(7): 1209-1212, 2023 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-37339140

RESUMO

PURPOSE: To describe the construction of a novel intraocular snare and evaluate its effectiveness in intraocular foreign body (IOFB) removal. METHOD: This is a retrospective consecutive case series. Five patients underwent pars plana vitrectomy and IOFB removal using the intraocular snare constructed from modified flute needle. RESULTS: All IOFBs were successfully engaged and removed with the snare on the first attempt. Three of the 5 cases (60%) enjoyed good visual outcome (0.4-1.0) postoperatively. No complication related to the use of the snare was encountered in this case series. CONCLUSION: Intraocular foreign body snare is simple, safe, and effective in IOFB removal.


Assuntos
Corpos Estranhos no Olho , Ferimentos Oculares Penetrantes , Humanos , Estudos Retrospectivos , Ferimentos Oculares Penetrantes/diagnóstico , Ferimentos Oculares Penetrantes/cirurgia , Ferimentos Oculares Penetrantes/complicações , Corpos Estranhos no Olho/diagnóstico , Corpos Estranhos no Olho/cirurgia , Vitrectomia , Microcirurgia
2.
J Am Psychiatr Nurses Assoc ; : 10783903231194579, 2023 Aug 24.
Artigo em Inglês | MEDLINE | ID: mdl-37615199

RESUMO

BACKGROUND: Suboptimal mental health literacy levels among general hospital health care professionals negatively impact the care coordination of patients with physical-mental comorbidity. AIMS: This review is to examine the evidence on the effectiveness of interventions to improve the mental health literacy of general hospital health care professionals. METHODS: A systematic search of literature was conducted in 13 electronic databases with manual searching of reference lists from 1980 to 2021. Studies were screened by pre-set eligibility criteria, that is, participants who were general hospital health care professionals taking care of adult patients, the interventions aimed at improving any components of participants' mental health literacy, comparisons were alternative active intervention or no intervention, and the primary outcomes were any aspects of mental health literacy. RESULTS: Eight randomized controlled trials (N = 1,732 participants) were included in this review. Evidence indicated that mental health literacy interventions with educational components can improve components of the health care professionals' mental health literacy, in terms of mental health knowledge and mental illness-related attitudes/stigma. In addition, few studies evaluated all components of participants' mental health literacy. CONCLUSIONS: Based on the available evidence, educational interventions had a positive effect on components of general hospital health care professionals' mental health literacy. Health care organizations should provide educational programs to enhance general hospital health care professionals' mental health literacy. Further studies are needed to explore interventions that target all components of general hospital staff's mental health literacy and to evaluate its impact on the psychiatric consultation-liaison service utilization in general hospitals, as well as patient outcomes.

3.
Rev Endocr Metab Disord ; 23(3): 541-567, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-35066781

RESUMO

Thyroid Eye Disease (TED) is an autoimmune disease that affects the extraocular muscles and periorbital fat. It most commonly occurs with Graves' Disease (GD) as an extrathyroidal manifestation, hence, it is also sometimes used interchangeably with Graves' Ophthalmopathy (GO). Well-known autoimmune markers for GD include thyroid stimulating hormone (TSH) receptor antibodies (TSH-R-Ab) which contribute to hyperthyroidism and ocular signs. Currently, apart from radiological investigations, detection of TED is based on clinical signs and symptoms which is largely subjective, with no established biomarkers which could differentiate TED from merely GD. We evaluated a total of 28 studies on potential biomarkers for diagnosis of TED. Articles included were published in English, which investigated clinical markers in tear fluid, orbital adipose-connective tissues, orbital fibroblasts and extraocular muscles, serum, thyroid tissue, as well as imaging biomarkers. Results demonstrated that biomarkers with reported diagnostic power have high sensitivity and specificity for TED, including those using a combination of biomarkers to differentiate between TED and GD, as well as the use of magnetic resonance imaging (MRI). Other biomarkers which were upregulated include cytokines, proinflammatory markers, and acute phase reactants in subjects with TED, which are however, deemed less specific to TED. Further clinical investigations for these biomarkers, scrutinising their specificity and sensitivity on a larger sample of patients, may point towards selection of suitable biomarkers for aiding detection and prognosis of TED in the future.


Assuntos
Doença de Graves , Oftalmopatia de Graves , Biomarcadores/análise , Doença de Graves/diagnóstico , Doença de Graves/metabolismo , Oftalmopatia de Graves/diagnóstico , Oftalmopatia de Graves/metabolismo , Humanos , Tireotropina/metabolismo
4.
Int Ophthalmol ; 39(3): 623-630, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29435797

RESUMO

INTRODUCTION: An increasing number of patients are taking novel oral anticoagulant (NOAC) medication, making perioperative management in phacoemulsification surgery an important issue. This study reports the haemorrhagic complications of NOAC in phacoemulsification surgery. DESIGN: Retrospective case study over a 4-year period. METHODS: Consecutive cases receiving NOAC during the time of phacoemulsification were reviewed. Patients were either advised to continue medications (continued group) or withhold medications before surgery (withheld group). MAIN OUTCOME MEASURES: Details including patient demographics, preoperative assessment, postoperative outcome and intraoperative, postoperative and systemic complications were recorded. RESULTS: A total of 20,100 cases of phacoemulsification were performed. Of which, 66 cases were found to be on NOAC (0.33%). This included 66 eyes of 53 patients, with 42 continued and 24 withheld medications before surgery. There was no statistically significant difference between the two groups in demographics, cataract risk factors, baseline renal function, clotting profile, type of NOAC, incision size, phacoemulsification energy, preoperative and postoperative visual acuity. There was also no significant difference in intraoperative, postoperative and systemic complications (p = 1.00 and 0.53, Fischer's exact test). None of the patients in the continued group had postoperative complications; two cases in the withheld group receiving retrobulbar anaesthesia had bruising and subconjunctival haemorrhage after resumption of NOAC (p = 0.13, Fischer's exact test). CONCLUSION: The present study found no difference in haemorrhagic complications between cases continuing and withholding NOAC during phacoemulsification. Nevertheless, the potential risks and benefits to continue or withhold NOAC perioperatively should be carefully considered via a multidisciplinary approach.


Assuntos
Anticoagulantes/administração & dosagem , Perda Sanguínea Cirúrgica/estatística & dados numéricos , Catarata/complicações , Facoemulsificação/métodos , Hemorragia Pós-Operatória/epidemiologia , Medição de Risco/métodos , Tromboembolia/prevenção & controle , Administração Oral , Idoso , Anticoagulantes/efeitos adversos , Feminino , Seguimentos , Hong Kong/epidemiologia , Humanos , Incidência , Masculino , Hemorragia Pós-Operatória/etiologia , Estudos Retrospectivos , Tromboembolia/complicações , Fatores de Tempo
5.
Int Ophthalmol ; 39(1): 41-46, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29230617

RESUMO

PURPOSE: Transscleral cyclodiode laser cyclophotocoagulation (TSCP) is often reserved for treatment of refractory glaucoma. This retrospective study investigates the safety and efficacy of TSCP among the Chinese population. METHODS: A retrospective review was performed on electronic patient records of all patients receiving TSCP between years 2009 to year 2016. Patient demographics, indication for laser, success and response rate, change in intraocular pressure (IOP), number of treatment sessions, laser energy, glaucoma medication, visual acuity, pain symptoms and complication rate were documented. RESULTS: The study included 126 patients: 81 patients were male and 45 were female, and the mean age was 66.6 ± 14.3 years old and the mean follow-up was 22.7 ± 14.1 months. The mean number of treatment sessions was 1.5 ± 0.8. The success rate was 67.3%. The mean IOP before TSCP was 67 ± 38.6 mmHg and 22.8 ± 14.2 mmHg after TSCP, the mean IOP reduction was 38.4%, which was statistically significant (P value < 0.001, Wilcoxon signed rank test). The mean laser energy used per eye was 72.7 ± 56.6 and 49.2 ± 22.9 J per individual treatment session. The mean number of laser shots was 15.0 ± 6.1. 71% of patients were able to reduce their glaucoma medication after TSCP, (P value < 0.01, Wilcoxon signed rank test). 86.1% of patients had improvement in pain symptoms after TSCP. The overall complication rate was 7.1%. CONCLUSION: TSCP was found to be safe and effective among the Chinese population, with comparably low laser energy setting and complication rate. It was found to be most effective in treatment of glaucoma due to trauma, acute angle closure, uveitis and chronic angle closure.


Assuntos
Corpo Ciliar/cirurgia , Cirurgia Filtrante/métodos , Glaucoma/cirurgia , Pressão Intraocular/fisiologia , Fotocoagulação a Laser/métodos , Lasers Semicondutores/uso terapêutico , Esclera/cirurgia , Idoso , China/epidemiologia , Feminino , Seguimentos , Glaucoma/epidemiologia , Glaucoma/fisiopatologia , Humanos , Incidência , Masculino , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , Fatores de Tempo , Resultado do Tratamento , Acuidade Visual
6.
BMC Ophthalmol ; 18(1): 329, 2018 Dec 19.
Artigo em Inglês | MEDLINE | ID: mdl-30567578

RESUMO

BACKGROUND: To describe the effectiveness of combined pentagonal resection and inferior retractor plication (PR + IRP) based on the Hill's procedure for the treatment of primary involutional lower eyelid entropion in the Chinese population. METHODS: This is a retrospective review of 52 eyelids of 46 patients who underwent PR + IRP for treatment of involutional entropion between May 2009 and May 2017. Patient demographics, presence of pre-operative laxity, post-operative outcome and presence of complications were all recorded from electronic patient records. RESULTS: A total of 52 eyelids of 46 patients received PR + IRP. None had recurrence of entropion, 1 (2.1%) had residual entropion, 2 eyelids (4.4%) had lower eyelid notching, 1 eyelid (2.2%) had infection and 1 eyelid (2.2%) had overcorrection. The overall success rate was 90.4%. CONCLUSION: Combined PR + IRP is an effective surgical procedure for primary involutional entropion with low recurrence rate. However, it may carry risk of eyelid notching post-operatively.


Assuntos
Entrópio/cirurgia , Pálpebras/cirurgia , Músculos Oculomotores/cirurgia , Procedimentos Cirúrgicos Oftalmológicos/métodos , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Humanos , Masculino , Microcirurgia , Pessoa de Meia-Idade , Estudos Retrospectivos , Retalhos Cirúrgicos , Técnicas de Sutura
7.
Jpn J Ophthalmol ; 68(3): 174-182, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38658452

RESUMO

PURPOSE: To evaluate the influence of systemic factors on macular vessel density in quantitative Optical Coherence Tomography Angiography (OCTA) by sex. STUDY DESIGN: A cross-sectional study. METHODS: A total of 2018 adults were recruited in this study. Participants were excluded (n=964) due to missing data, eye-related problems, or low OCTA scan quality. Macular vessel densities were measured with OCTA using split-spectrum amplitude decorrelation angiography algorithm. Only the data from the right eyes were selected for analysis. Multivariable linear regression analysis was performed to determine the associations between macular vessel density and obesity-related systemic factors in each gender group. RESULTS: The right eyes of 1054 participants (59.6% women) were enrolled. Men had significantly higher obesity parameters and associated risk factors. In multivariable linear regression analysis in men, older age and type 2 diabetes mellitus were independently associated with lower superficial retinal vessel density (ß = -0.37, p = 0.002; ß = -1.22, p = 0.03) and deep retinal vessel density, respectively (ß = -0.66, p < 0.001; ß = -1.76, p = 0.02); positive association was also observed between body mass index (BMI) and superficial retinal vessel density (ß = 0.56, p = 0.02). In women, only higher systolic blood pressure was independently associated with a lower deep retinal vessel density (ß = -0.50, p = 0.003). CONCLUSIONS: This large cross-sectional study shows that older age and type 2 diabetes mellitus are associated with lower superficial and deep retinal capillary vessel density in men. This may help clinicians better understand how systemic factors influence retinal vessel density in different genders and future studies can ascertain more potential sex differences.


Assuntos
Angiofluoresceinografia , Macula Lutea , Vasos Retinianos , Tomografia de Coerência Óptica , Humanos , Masculino , Estudos Transversais , Feminino , Tomografia de Coerência Óptica/métodos , Vasos Retinianos/diagnóstico por imagem , Pessoa de Meia-Idade , Angiofluoresceinografia/métodos , Fatores Sexuais , Macula Lutea/irrigação sanguínea , Macula Lutea/diagnóstico por imagem , Fundo de Olho , Idoso , Adulto , Fatores de Risco , Índice de Massa Corporal , Densidade Microvascular , Vigilância da População , Estudos Retrospectivos
8.
Transl Vis Sci Technol ; 12(9): 10, 2023 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-37713187

RESUMO

Purpose: This cross-sectional study aimed to investigate the sectoral variance of optical coherence tomography (OCT) and OCT angiography (OCTA) glaucoma diagnostic parameters across eyes with varying degrees of refractive error. Methods: Healthy participants, including individuals with axial ametropia, enrolled in the Hong Kong FAMILY cohort were imaged using the Avanti/AngioVue OCT/OCTA system. The OCT and OCTA parameters obtained include peripapillary nerve fiber layer thickness (NFLT), peripapillary nerve fiber layer plexus capillary density (NFLP-CD), and macular ganglion cell complex thickness (GCCT). Sectoral measurements of NFLT, NFLP-CD, and GCCT were based on sectors and hemispheres. Results: A total of 1339 eyes from 791 participants were stratified based on spherical equivalent refraction: high myopia (<-6 D), low myopia (-6 D to -1 D), emmetropia (-1 D to 1 D), and hyperopia (>1 D). Multivariable broken stick regression models, accounting for age, sex, and signal strength, showed that all NFLT sectors except temporally, the inferior GCCT hemisphere, and half of the NFLP-CD sectors were more affected by ametropia-related covariates than the corresponding global parameters. As expected, the false-positive rates in those sectors were elevated. Finally, sector-specific axial length (AL) and spherical equivalent (SE) adjustments helped reduce the elevated false-positive rates. Conclusions: The effect of optical magnification is even more prominent among sectors than the global parameters. AL- and SE-based adjustments should be individualized to each sector to mitigate this magnification bias effectively. Translational Relevance: Identifying sectoral differences among diagnostic parameters and adopting these sector-based adjustments into commercial OCT systems will hopefully reduce false-positive rates related to refractive error.


Assuntos
Glaucoma , Miopia , Erros de Refração , Humanos , Tomografia de Coerência Óptica , Estudos Transversais , Erros de Refração/diagnóstico , Glaucoma/diagnóstico , Angiografia
9.
Br J Ophthalmol ; 106(10): 1411-1416, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-34016574

RESUMO

PURPOSE: To investigate the optic disc and peripapillary vessel density, as well as its ocular and systemic associations, in healthy eyes among adult Chinese population. METHODS: A population-based cross-sectional eye survey was conducted on Chinese adults residing in Hong Kong. 1891 eyes from 1891 participants who completed 4.5×4.5 mm optical coherence tomography angiography scans were recruited. Among the 1891 eyes, 404 were excluded due to low scan quality, optic disc or retinal disorders and non-Chinese ethnicity. The vessel densities (VDs) at nerve fibre layer plexus (NFLP) at both optic disc and peripapillary were collected for analysis. Multiple linear regression analysis was performed to determine the ocular and systemic associations of NFLP VD. RESULTS: The study included 1487 participants (men: 41.2%) with a mean age of 48.8±15.4 years. The mean NFLP VD of the whole en face image, inside disc and peripapillary region was 53.8%, 42.7% and 60.3%, respectively. In the multivariable model, decreased NFLP VDs were significantly associated with older age, male gender, longer axial length (AL) and lower Signal Strength Index. CONCLUSIONS: This large population-based cross-sectional study provided quantitative data of optic disc and peripapillary NFLP VD which may serve as a normative reference for clinical use. Apart from age, gender and AL, the scan signal strength also should be taken into consideration during the assessment of NFLP VD.


Assuntos
Disco Óptico , Adulto , Estudos Transversais , Angiofluoresceinografia/métodos , Humanos , Pressão Intraocular , Masculino , Pessoa de Meia-Idade , Vasos Retinianos/diagnóstico por imagem , Tomografia de Coerência Óptica/métodos
10.
Transl Vis Sci Technol ; 11(9): 8, 2022 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-36112104

RESUMO

Purpose: The purpose of this study was to correct refractive error-associated bias in optical coherence tomography (OCT) and OCT angiography (OCTA) glaucoma diagnostic parameters. Methods: OCT and OCTA imaging were obtained from participants in the Hong Kong FAMILY cohort. The Avanti/AngioVue OCT/OCTA system was used to measure the peripapillary nerve fiber layer thickness (NFLT), peripapillary nerve fiber layer plexus capillary density (NFLP-CD), macular ganglion cell complex thickness (GCCT), and macular superficial vascular complex vascular density (SVC-VD). Healthy eyes, including ones with axial ametropia, were enrolled for analysis. Results: A total of 1346 eyes from 792 participants were divided into 4 subgroups: high myopia (<-6D), low myopia (-6D to -1D), emmetropia (-1D to 1D), and hyperopia (>1D). After accounting for age, sex, and signal strength, multivariable regression showed strong dependence in most models for NFLT, GCCT, and NFLP-CD on axial eye length (AL), spherical equivalent (SE) refraction, and apparent optic disc diameter (DD). Optical analysis indicated that AL-related transverse optical magnification variations predominated over anatomic variations and were responsible for these trends. Compared to the emmetropic group, the false positive rates were significantly (Chi-square test P < 0.003) elevated in both myopia groups for NFLT, NFLP-CD, and GCCT. Regression-based adjustment of these diagnostic parameters with AL or SE significantly (McNemar test P < 0.03) reduced the elevated false positive rates. Conclusions: Myopic eyes are biased to have lower NFLT, GCCT, and NFLP-CD measurements. AL- and SE-based adjustments were effective in mitigating this bias. Translational Relevance: Adoption of these adjustments into commercial OCT systems may reduce false positive rates related to refractive error.


Assuntos
Glaucoma , Miopia , Disco Óptico , Erros de Refração , Angiografia , Glaucoma/diagnóstico , Humanos , Miopia/diagnóstico por imagem , Disco Óptico/diagnóstico por imagem , Erros de Refração/diagnóstico , Tomografia de Coerência Óptica
11.
Ophthalmic Epidemiol ; 27(5): 354-363, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32310706

RESUMO

PURPOSE: To investigate the prevalence, associations, and causes of visual impairment and blindness in the adult population of Hong Kong. METHODS: This cross-sectional population-based study included 2018 (870, 43% male) randomly selected adults with a mean age 52 ± 16 years (range 18-90 years) in Hong Kong. Each participant underwent comprehensive ophthalmic examinations. Presenting visual acuity (PVA) and best-corrected visual acuity (BCVA) of each eye was recorded. Prevalence of visual impairment and blindness was calculated using both World Health Organization (WHO) and United States (US) definitions, based on BCVA and PVA. RESULTS: Visual acuity measurements were available for 1952 (96.8%) participants. The prevalence of visual impairment, based on BCVA value, using WHO and US definition, was 1.0 ± 0.1% and 2.7 ± 0.4%, respectively. The prevalence of visual impairment, based on PVA value, was 5.1 ± 0.5% and 14.0 ± 0.8%, using WHO and US definition, respectively. Multivariate analysis demonstrated the presence of visual impairment (PVA, WHO definition) increased significantly with older age (odds ratio 1.039, P < .001) and thinner central cornea thickness (odds ratio 0.994, P = .014), but not significantly associated with other socioeconomic, systemic or ocular parameters after adjusting for age and central corneal thickness. Under-correction of refractive error was the most common reason for presenting visual impairment. Causes of impaired BCVA were cataract (37%), age-related macular degeneration (26%), diabetic macular edema (11%), glaucoma (11%), epiretinal membrane (5%), and unknown (11%). CONCLUSION: The prevalence of visual impairment in Hong Kong increased significantly with older age and thinner central corneal thickness. The major causes for impairment were under-correction of refractive error, cataract, and age-related macular degeneration.


Assuntos
Cegueira , Catarata , Retinopatia Diabética , Edema Macular , Baixa Visão , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Cegueira/epidemiologia , China , Estudos Transversais , Feminino , Hong Kong/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Baixa Visão/epidemiologia , Adulto Jovem
12.
Eye (Lond) ; 33(9): 1433-1442, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-30952958

RESUMO

PURPOSE: To determine the practice patterns of ophthalmic plastic surgeons regarding the management of eyelid sebaceous carcinoma (SC). METHODS: An electronic survey was distributed to oculoplastic surgical colleagues in the Asia Pacific region requesting clinical information and treatment approaches to SC. RESULTS: The responses from 192 respondents from the Asia Pacific region was included and analyzed in this study. For initial diagnosis, most surgeons selected incisional biopsy (55%), followed by complete excision (35%). Initial workup was mainly by palpation of lymph nodes, chest X-ray, and computerized tomography scan (CT-scan) of the orbit. Conjunctival map biopsy was done in selected cases. Sentinel lymph node biopsy (SLNB) was done mainly for tumors larger than 10 mm. Management was mainly by surgical excision (5 mm margin) combined with adjuvant therapy in some cases, with radiotherapy being the most common. Margin status was determined most frequently by frozen section as evaluated by the pathologist (57%) followed by Mohs micrographic surgery (18%). Surveillance was based mainly on physical examination alone. CONCLUSION: The Asia Pacific oculoplastic surgeons prefer incisional biopsy for lesions suspicious of SC prior to definitive surgery. This is in contrast to survey results previously reported in other populations. Frozen section control (done by an oculoplastic surgeon with pathology support) is most commonly used for margin control and conjunctival map biopsies are done only in selected cases. Despite the potential benefits of SLNB, access and expertise in this area is currently lacking in the Asia Pacific region.


Assuntos
Adenocarcinoma Sebáceo/cirurgia , Neoplasias Palpebrais/cirurgia , Padrões de Prática Médica/estatística & dados numéricos , Neoplasias das Glândulas Sebáceas/cirurgia , Adenocarcinoma Sebáceo/diagnóstico por imagem , Adenocarcinoma Sebáceo/patologia , Idoso , Ásia/epidemiologia , Terapia Combinada , Neoplasias Palpebrais/diagnóstico por imagem , Neoplasias Palpebrais/patologia , Feminino , Pesquisas sobre Atenção à Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Oftalmológicos , Oceano Pacífico , Radioterapia , Neoplasias das Glândulas Sebáceas/diagnóstico por imagem , Neoplasias das Glândulas Sebáceas/patologia , Biópsia de Linfonodo Sentinela , Inquéritos e Questionários , Tomografia Computadorizada por Raios X
13.
Medicine (Baltimore) ; 98(47): e17993, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31764812

RESUMO

This study aims to establish the range of exophthalmometry values (EV) in the adult Hong Kong (HK) Chinese population, its relationship with various anthropometric parameters, and to compare it with the EV in different ethnic groups.About 1485 adult HK Chinese were drawn from a random sample from the community-based FAMILY Cohort. Participants were interviewed, and comprehensive ophthalmological assessments were conducted. EV was measured using the Hertel's exophthalmometer.EV of both eyes from 630 male (42.4%) and 855 female (57.6%) participants, mean age 54 ±â€Š17.2 and 52 ±â€Š16 respectively were analyzed. The mean EV were found to be 15.3 ±â€Š2.8 mm in the right eye, 15.2 ±â€Š2.9 mm in the left eye for men and 14.4 ±â€Š2.7 mm in the right eye, 14.3 ±â€Š2.7 mm in the left eye for women. There were no differences in the EV between right and left eyes (P > .05). Men had significantly higher EV than women (P < .05) and age was found to be negatively correlated to EV (P < .05). Body height (r = 0.20), weight (r = 0.25), waist (r = 0.11), hip circumference (r = 0.15), body mass index (r = 0.17), interpupillary distance (r = 0.54), and axial length (AL) (r = 0.20) were all found to have statistically significant positive correlations with EV (P < .01). Spherical equivalent was found to have statistically significant negative correlation with EV (P < .01).Our study provides normative data on EV in the HK Chinese population. Height, weight, interpupillary distance, waist, hip circumference, and AL had positive correlations with EV. Spherical equivalent had negative correlation with EV. There was no significant difference in EV between the right and left eye. Age and gender had significant effect on EV.


Assuntos
Exoftalmia/patologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Povo Asiático , Técnicas de Diagnóstico Oftalmológico , Etnicidade , Feminino , Hong Kong , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
14.
Invest Ophthalmol Vis Sci ; 60(14): 4830-4837, 2019 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-31747685

RESUMO

Purpose: We investigate macular perfusion and the systemic and ocular associations in a population-based setting. Methods: In this cross-sectional study, 2018 adults residing in Hong Kong underwent detailed ophthalmic examinations after consenting to participate. Macular perfusion was measured with optical coherence tomography angiography (OCTA) using the split-spectrum amplitude decorrelation angiography algorithm. The parafoveal flow index and vessel area density were quantified using automated custom-built software. Results: Of the 2018 participants, the OCTA measurements were available for 1940, and 1631 (84.1%) had good quality scans. The right eyes of these 1631 participants (43.1% men) were included for final analysis. Mean age was 49.8 years (range, 18-92 years). Mean global macular vessel density was 47.3% and 55.1% for the superficial and deep retinal layers, respectively. In multivariate analysis, lower superficial vessel density remained significantly associated with lower signal strength index (SSI; P < 0.001, standardized ß = 0.607) and male sex (P < 0.001, ß = 0.162), and borderline associated with older age (P = 0.09, ß = -0.045) and longer axial length (AL; P = 0.09, ß = -0.037), while lower deep layer vessel density was significantly associated with lower SSI (P < 0.001, standardized ß = 0.667), longer AL (P < 0.001, ß = -0.097), and higher creatinine (P < 0.001, ß = -0.072). Conclusions: This large population-based study provided normative OCTA data of macular vessel density and demonstrated that a lower superficial retinal vessel density was significantly associated with lower SSI and male sex, while a lower deep layer retinal vessel density was significantly associated with lower SSI, longer AL, and higher level of creatinine. These associations must be considered when interpreting clinical quantitative OCTA data.


Assuntos
Angiofluoresceinografia , Macula Lutea/irrigação sanguínea , Vasos Retinianos/anatomia & histologia , Tomografia de Coerência Óptica , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Capilares/anatomia & histologia , Capilares/diagnóstico por imagem , Creatinina/sangue , Estudos Transversais , Feminino , Angiofluoresceinografia/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Valores de Referência , Fluxo Sanguíneo Regional/fisiologia , Retina/fisiologia , Vasos Retinianos/diagnóstico por imagem , Lâmpada de Fenda , Tomografia de Coerência Óptica/métodos , Adulto Jovem
16.
J Ophthalmol ; 2017: 1261698, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28465832

RESUMO

Purpose. To study whether nurse led same-day review (SDR) after uneventful phacoemulsification can replace next-day review (NDR) in terms of safety and efficacy. Setting. Patients are recruited from an ophthalmology outpatient clinic in Hong Kong. Design. A prospective, randomized crossover study conducted from November 2012 to 2014. Methods. Inclusion criteria include cataract surgery naïve patients undergoing phacoemulsification under local anaesthesia. All patients were seen by our ophthalmic nurse 2 hours after surgery. Before undergoing phacoemulsification of the first eye, patients were randomized to be reviewed on day 1 or 7 after surgery. Surgeons and reviewing doctors were blinded to patient allocation. For the patients' second eye surgery, group allocation will cross over. Primary outcome measures include visual improvement and patient satisfaction questionnaire. Other measures include cataract characteristics, surgical details, and complications. Statistical tests include paired t-test, Wilcoxon signed rank test, and Chi-square test. Results. 164 eyes from 82 patients were available. Visual improvement, satisfaction, and complications were comparable between both groups. Conclusions. A nurse led SDR can replace NDR in uneventful phacoemulsification in terms of safety and efficacy. Patient satisfaction is also comparable in the setting of Asian culture and when transportation is not a major concern.

17.
Physiother Can ; 67(2): 157-66, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25931667

RESUMO

PURPOSE: To describe the nature, extent, and impact of spasticity; determine factors that are perceived to influence its severity; and examine the relationship between time since diagnosis and impact of spasticity on daily activities in people with stroke and multiple sclerosis (MS) who are receiving botulinum toxin injection treatments. METHODS: After a cross-sectional telephone survey, descriptive statistics and correlations were analyzed separately for the stroke and MS groups. RESULTS: A total of 29 people with stroke and 10 with MS were surveyed. Both groups perceived increased spasticity with outdoor cold (69% stroke, 60% MS), muscle fatigue (59% stroke, 80% MS), and mental stress (59% stroke, 90% MS). No statistically significant correlations were found between time since diagnosis and perceived impact of spasticity on function in the stroke (r=0.07, p=0.37) or MS (r=0.16, p=0.33) groups. The MS group experienced bilateral and more severe perception of spasticity in the legs than the stroke group and identified more factors as worsening their spasticity (p<0.05). Severity of leg (but not arm) spasticity was significantly correlated with severity of impact of the following factors in the MS group only: lying on the back (r=0.70, p<0.05), outdoor heat (r=0.61, p<0.05), and morning (r=0.59, p<0.05). CONCLUSION: Intrinsic and extrinsic triggers can influence the perception of spasticity differently depending on individual factors, severity, location (arm vs. leg), and distribution of spasticity (unilateral vs. bilateral). Clinicians can use the findings to better understand, educate, and treat people with stroke and MS.


Objet : Décrire la nature, l'étendue et l'effet de la spasticité; déterminer les facteurs qui, croit-on, ont un effet sur sa gravité; examiner le lien entre le temps écoulé depuis le diagnostic et l'effet de la spasticité sur les activités quotidiennes chez des personnes qui avaient subi un accident vasculaire cérébral et chez d'autres qui avaient la sclérose en plaques (SP) et qui reçoivent des traitements par injection de toxine botulique. Méthodes : À la suite d'un sondage téléphonique transversal, on a analysé des statistiques descriptives et des corrélations séparément pour les patients qui avaient subi un accident vasculaire cérébral et ceux qui avaient la SP. Résultats : Au total, on a sondé 29 personnes victimes d'un accident vasculaire cérébral et 10 autres qui avaient la SP. Les deux groupes ont perçu une spasticité accrue par temps froid à l'extérieur (69 % accident vasculaire cérébral, 60 % SP), de la fatigue musculaire (59 % accident vasculaire cérébral, 80 % SP) et du stress mental (59 % accident vasculaire cérébral, 90 % SP). On n'a constaté aucune corrélation statistiquement significative entre le temps écoulé depuis le diagnostic et l'effet perçu de la spasticité sur le fonctionnement chez les groupes de patients qui avaient subi un accident vasculaire cérébral (r=0,07, p=0,37) ou qui avaient la SP (r=0,16, p=0,33). Les personnes qui avaient la SP avaient une perception bilatérale et plus grave de la spasticité dans les jambes que celles qui avaient subi un accident vasculaire cérébral et elles ont indiqué un plus grand nombre de facteurs qui aggravaient leur spasticité (p<0,05). On a établi une corrélation significative entre la gravité de la spasticité des jambes (mais non des bras) et la gravité de l'effet des facteurs suivants chez les personnes qui avaient la SP seulement: position couchée sur le dos (r=0,70, p<0,05), chaleur à l'extérieur (r=0,61, p<0,05) et l'avant-midi (r=0,59, p<0,05). Conclusion : Des facteurs déclencheurs intrinsèques et extrinsèques peuvent avoir un effet sur la perception de la spasticité qui diffère selon les facteurs individuels, la gravité, l'endroit atteint (bras ou jambe) et l'étendue de la spasticité (unilatérale ou bilatérale). Les cliniciens peuvent utiliser les constatations pour mieux comprendre, informer et traiter les personnes qui ont subi un accident vasculaire cérébral et celles qui ont la SP.

20.
Open Orthop J ; 7: 521-9, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24133553

RESUMO

Neck pain is a significant societal burden due to its high prevalence and healthcare costs. While physical activity can help to manage other forms of chronic musculoskeletal pain, little data exists on the relationship between physical activity and neck pain. The purpose of this study was to compare physical activity levels between individuals with neck pain and healthy controls, and then to relate disability, fear of movement, and pain sensitivity measures to physical activity levels in each of the two participant groups. 21 participants were recruited for each of the two participant groups (n = 42). Data collection included the use of the Neck Disability Index, the Tampa Scale for Kinesiophobia, electrocutaneous (Neurometer® CPT) and pressure stimulation (JTech algometer) for quantitative sensory testing, and 5 days of subjective (Rapid Assessment of Physical Activity) and objective (BioTrainer II) measurements of physical activity. Analysis of Variance and Pearson's Correlation were used to determine if differences and relationships exist between dependent variables both within and between groups. The results show that individuals with mild neck pain and healthy controls do not differ in subjectively and objectively measured physical activity. While participants with neck pain reported higher neck disability and fear of movement, these factors did not significantly relate to physical activity levels. Perceived activity level was related to pain threshold and tolerance at local neck muscles sites (C2 paraspinal muscle and upper trapezius muscle), whereas measured activity was related to generalized pain sensitivity, as measured at the tibialis anterior muscle site.

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