Detalhe da pesquisa
1.
Discovery of 4-alkylamino-7-aryl-3-cyanoquinoline LRRK2 kinase inhibitors.
Bioorg Med Chem Lett
; 23(7): 1974-7, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23453068
2.
Reducing prophylactic antibiotics use in laparoscopic cholecystectomy and liver resections.
Eur J Gastroenterol Hepatol
; 33(4): 533-534, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32398496
3.
Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model.
Bioorg Med Chem Lett
; 20(21): 6231-6, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20833041
4.
Tumors establish resistance to immunotherapy by regulating Treg recruitment via CCR4.
J Immunother Cancer
; 8(2)2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33243932
5.
Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors.
J Med Chem
; 63(15): 8584-8607, 2020 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32667798
6.
Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment.
J Med Chem
; 62(13): 6190-6213, 2019 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31259550
7.
Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system.
J Biol Chem
; 284(5): 2598-2602, 2009 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19004816