Intimate Partner Violence, prevalence and its consequences: a community-based study in Gambella, Ethiopia.

Introduction: Intimate partner violence is defined as any behavior by a current or past male intimate partner during marriage, cohabitation, or any other formal or informal union that causes physical, sexual, or psychological harm. Men are the most common perpetrators of this against women. It affects almost one-third of all women worldwide. Objective: This study aimed to assess the prevalence, consequences, and factors associated with intimate partner violence among partnered women in Gambella town. Methods: A community-based, cross-sectional study design was employed. A systematic random sampling technique was used to select the study participants. Data was collected using a pretested, structured questionnaire. The data were entered and analyzed using SPSS software version 25. The bivariate and multivariate logistic regression method was used to identify factors associated with intimate partner violence. Variables with a p-value <0.05 were considered significantly associated with intimate partner violence. Results: The overall prevalence of intimate partner violence in the lifetime and the last 12 months was 58.8, 95% CI (54.0, 63.6), and 51.8, 95% CI (46.7, 56.8), respectively. More than half (53.3%) of the violence resulted in physical injury, while 32.9% were separated from their partners whereas, mother's history of exposure to IPV [AOR: 1.8, 95% CI (1.03-3.27), p < 0.05], respondent's age [AOR: 3.4, 95% CI (1.8, 6.5), p < 0.001], substance use [AOR:2.5, 95% CI (1.5-4.1), p < 0.001], disagreement on sexual intercourse [AOR:3.2, 95% CI (1.8-5.7), p < 0.01], monthly family income [AOR:0.32, 95% CI: (0.16-0.63), p < 0.01] and family size [AOR:2.8, 95% CI: (1.6-4.8), p < 0.01] were significantly associated with IPV. Conclusion: The study indicated that the prevalence of intimate partner violence was very high. Age of the woman, family size, substance use, economic status, were among factors significantly associated with intimate partner violence. Therefore, responsible stakeholders should respond to the deep-rooted and highly complicated gender inequality by implementing preventive measures.

Self-Medication and Associated Factors Among Pregnant Women in Rural Ethiopia: The Importance of Husband Education in Ensuring a Safe Pregnancy.

Background: Self-medication is the use of drugs without a medical prescription to treat self-identified illnesses; it is also the continued use of drugs without a physician's order for recurring symptoms, either by sharing or purchasing them from unlicensed vendors. It entails substantial risk to pregnant women and fetuses. Magnitude of the problem and its factors among rural pregnant women is not studied in Ethiopia. Objective: This study aimed to assess the prevalence of self-medication practice and identify its associated factors among pregnant women in rural Southwest Shewa, Ethiopia. Methods: A cross-sectional study was conducted on 585 randomly selected pregnant women in selected rural public health institutions from May to July 2021. Data was collected by using an interviewer-administered pretested structured questionnaire. Multivariable logistic regression was used to identify factors associated with self-medication. Variables with p-value <0.05 for the 95% confidence interval of the adjusted odds ratio were considered statistically significant. Results: A total of 585 pregnant women participated in the study with a response rate of 92.3%. The prevalence of self-medication among pregnant women was 19.8%. Primigravidity (AOR = 2.7, 95% CI: 1.2-6.1), lower educational status of husbands (AOR = 3.6, 95% CI: 1.02-12.9), living close to health facilities (AOR = 0.23, 95% CI: 0.09-0.6) and knowing one's own gestational age (AOR = 0.5,95% CI: 0.30-0.9) were significantly associated with self-medication practice. Conclusion and Recommendation: One in five of the pregnant women practiced self-medication during the current pregnancy. Primigravidity and lower educational status of husbands were associated with a higher probability of self-medication. Knowing gestational age and living close to health facilities were associated with a lower likelihood of practicing self-medication. Rational drug use has to be promoted among pregnant women. Maternal and child health interventions should also target husbands. Health education has to be strengthened to help pregnant women have a safe pregnancy.

Determinants of wasting among children aged 6-59 months in Wonago woreda, south Ethiopia. A facility-based unmatched case-control study.

BACKGROUND: Wasting continued to threaten the lives of 52 million (7.7%) under-five children globally. Sub-Saharan Africa accounts for one-third of all wasted children globally, and Ethiopia is among the countries with the highest magnitude of Wasting in the region. Despite, the little decrement in the prevalence of other forms of malnutrition (stunting and underweight), the burden of wasting remains the same in the country. Gedeo zone is among those with a high prevalence of under-five wasting. OBJECTIVE: To identify determinants of wasting among children aged 6-59 months in Wonago Woreda, 2018. METHODS: A facility-based unmatched case-control study was conducted from May 11 to July 21/2018. A total of 356 (119 cases and 237 controls) mothers/caregivers of under-five children who visited the Wonago woreda public health facilities were included in the study using systematic random sampling. Data were collected using a structured questionnaire and anthropometric measurement. Descriptive analysis was used to describe data. Binary logistic regression was used to identify determinants of wasting among children aged 6-59 months. Variables with p-value < 0.25 in bi-variate analysis entered to multivariate analysis. Those variables with a p-value less than 0.05 during the multivariate regression were considered significant. RESULTS: Determinants which found to have an association with wasting in this study were; maternal illiteracy [AOR = 2.48, 95% CI (1.11, 5.53)] family size <3 [AOR = 0.16, 95% CI (0.05, 0.50)] wealth index [AOR = 2.41, 95% CI (1.07, 5.46)] exclusive breastfeeding in the first 6 months [AOR = 2.71, 95% CI (1.15, 6.40)] dietary diversity [AOR = 5.52, 95% CI (2.06, 14.76)] and children been sick in the last 2 weeks [AOR = 4.36, 95% CI (2.21, 8.61)]. CONCLUSION AND RECOMMENDATIONS: Determinants identified were maternal education, family size, wealth index, and exclusive breastfeeding, dietary diversity, and morbidity history of a child in the last 2 weeks. To reduce childhood wasting, due emphasis should be given to empowering women and improving the knowledge and practice of parents on appropriate infant and young child-caring practices.

Evaluation of the Antimalarial Activity of Ethanol Extracts of the Leaves of Three Plant Species Collected from Yayu Coffee Forest Biosphere Reserve, Southwest Ethiopia.

OBJECTIVE: In the attempt of searching for potential plant derived antimalarial medicines, the aim of the present study was to examine In vivo antimalarial efficacy of crude ethanol extracts of the leaves of Croton macrostachyus, Ruta chalepensis and Vernonia amygdalina using chloroquine (CQ) sensitive strains of Plasmodium berghei in Swiss albino mice. METHODS: To ascertain the safety level of the plant materials, crude extracts underwent oral acute toxicity assessments whereby mice received up to a single dose of 3000 mg/kg. Peter's four day standard antimalarial suppressive test was carried out to determine growth inhibition of parasitemia at tested doses of 400, 600, and 800 mg/kg of the extracts. Survival time of experimental mice and preliminary phytochemical screenings of the extracts were also done according to the standard procedures. RESULTS: Extracts of the plant materials did not produce severe acute toxic effects in mice that received up to 3000 mg/kg in a single dose. Although complete clearance was not recorded, extracts of the plant materials produced dose dependent suppression of the parasitemia. The highest growth inhibition recorded was by extract of V. amygdalina (61.44%) followed by C. macrostachyus (59.3%) at 800 mg/kg of tested doses. Whereas, complete parasitemia clearance was attributed in mice treated with 25 mg/kg of CQ. In addition, survival time of experimental mice was recorded and the result showed mice treated with the extracts lived longer than the corresponding negative controls. The phytochemical screening of the extracts revealed the presence of antimalarial active constituents such as alkaloids, saponins, cardiac glycosides, flavonoids, terpenoids, steroids, phenols, and tannins. CONCLUSION: The present study, therefore, suggests that crude ethanol extracts of C. macrostachyus, R. chalepensis, and V. amygdalina are safe and rich with active secondary metabolites which have promising antimalarial effects.