Detalhe da pesquisa
1.
PDE10A Inhibition Reduces the Manifestation of Pathology in DMD Zebrafish and Represses the Genetic Modifier PITPNA.
Mol Ther
; 29(3): 1086-1101, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33221436
2.
Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries.
Bioorg Med Chem Lett
; 23(5): 1407-11, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23337601
3.
A selective cannabinoid-1 receptor antagonist, PF-95453, reduces body weight and body fat to a greater extent than pair-fed controls in obese monkeys.
J Pharmacol Exp Ther
; 335(1): 103-13, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20605903
4.
Discovery of N-benzyl-2-[(4S)-4-(1H-indol-3-ylmethyl)-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl]-N-isopropylacetamide, an orally active, gut-selective CCK1 receptor agonist for the potential treatment of obesity.
Bioorg Med Chem Lett
; 20(22): 6797-801, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20851601
5.
Galanin function in the central nervous system.
Curr Opin Drug Discov Devel
; 9(5): 560-70, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17002216
6.
Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example.
ACS Med Chem Lett
; 4(11): 1079-84, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900608
7.
Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists.
ACS Med Chem Lett
; 4(1): 63-8, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900564