Detalhe da pesquisa
1.
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Nat Chem Biol
; 15(6): 556-559, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31086327
2.
Targeting the lysyl oxidases in tumour desmoplasia.
Biochem Soc Trans
; 47(6): 1661-1678, 2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31754702
3.
Quantitation of Purines from Pigeon Guano and Implications for Cryptococcus neoformans Survival During Infection.
Mycopathologia
; 184(2): 273-281, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30707338
4.
GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans.
J Biol Chem
; 292(7): 3049-3059, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062578
5.
Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
J Biol Chem
; 292(28): 11829-11839, 2017 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28559277
6.
Antimicrobial Octapeptin C4 Analogues Active against Cryptococcus Species.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29158283
7.
Charting the unexplored extracellular matrix in cancer.
Int J Exp Pathol
; 99(2): 58-76, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29671911
8.
miRNAs in pancreatic cancer progression and metastasis.
Clin Exp Metastasis
; 2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38240887
9.
Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism.
Adv Sci (Weinh)
; : e2307963, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38602451
10.
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
Nat Cancer
; 4(9): 1326-1344, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37640930
11.
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis.
Nat Commun
; 13(1): 4587, 2022 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35933466
12.
Targeting Lysyl Oxidase Family Meditated Matrix Cross-Linking as an Anti-Stromal Therapy in Solid Tumours.
Cancers (Basel)
; 13(3)2021 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513979
13.
Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition.
Cancer Res
; 81(13): 3461-3479, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33980655
14.
The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development.
Cancer Rep (Hoboken)
; 3(1): e1209, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32671954
15.
Recent advances in understanding the complexities of metastasis.
F1000Res
; 72018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30135716
16.
Purine Acquisition and Synthesis by Human Fungal Pathogens.
Microorganisms
; 5(2)2017 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28594372
17.
Sirtuins in the phylum Basidiomycota: A role in virulence in Cryptococcus neoformans.
Sci Rep
; 7: 46567, 2017 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28429797
18.
Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D-F.
Phytochemistry
; 124: 79-85, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26743853
19.
Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans.
ACS Infect Dis
; 2(9): 651-663, 2016 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27759389
20.
A genomic safe haven for mutant complementation in Cryptococcus neoformans.
PLoS One
; 10(4): e0122916, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25856300