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BACKGROUND: Deep learning techniques can outperform traditional machine learning techniques and learn from unstructured and perceptual data, such as images and languages. We evaluated whether a convolutional neural network (CNN) model using whole axial brain T2-weighted magnetic resonance (MR) images as input data can help predict motor outcomes of the upper and lower limbs at the chronic stage in stroke patients. METHODS: We collected MR images taken at the early stage of stroke in 1,233 consecutive stroke patients. We categorized modified Brunnstrom classification (MBC) scores of ≥5 and functional ambulatory category (FAC) scores of ≥4 at 6 months after stroke as favorable outcomes in the upper and lower limbs, respectively, and MBC scores of <5 and FAC scores of <4 as poor outcomes. We applied a CNN to train the image data. Of the 1,233 patients, 70% (863 patients) were randomly selected for the training set and the remaining 30% (370 patients) were assigned to the validation set. RESULTS: In the prediction of upper limb motor function on the validation dataset, the area under the curve (AUC) was 0.768, and for lower limb motor function, the AUC was 0.828. CONCLUSION: We showed that a CNN model trained using whole-brain axial T2-weighted MR images of stroke patients would help predict upper and lower limb motor function at the chronic stage.
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Aprendizado Profundo , Acidente Vascular Cerebral , Humanos , Imageamento por Ressonância Magnética/métodos , Algoritmos , Encéfalo/diagnóstico por imagem , Acidente Vascular Cerebral/diagnóstico por imagemRESUMO
BACKGROUND: Deep learning (DL) is an advanced machine learning approach used in diverse areas, such as image analysis, bioinformatics, and natural language processing. A convolutional neural network (CNN) is a representative DL model that is advantageous for image recognition and classification. In this study, we aimed to develop a CNN to detect meniscal tears and classify tear types using coronal and sagittal magnetic resonance (MR) images of each patient. METHODS: We retrospectively collected 599 cases (medial meniscus tear = 384, lateral meniscus tear = 167, and medial and lateral meniscus tear = 48) of knee MR images from patients with meniscal tears and 449 cases of knee MR images from patients without meniscal tears. To develop the DL model for evaluating the presence of meniscal tears, all the collected knee MR images of 1048 cases were used. To develop the DL model for evaluating the type of meniscal tear, 538 cases with meniscal tears (horizontal tear = 268, complex tear = 147, radial tear = 48, and longitudinal tear = 75) and 449 cases without meniscal tears were used. Additionally, a CNN algorithm was used. To measure the model's performance, 70% of the included data were randomly assigned to the training set, and the remaining 30% were assigned to the test set. RESULTS: The area under the curves (AUCs) of our model were 0.889, 0.817, and 0.924 for medial meniscal tears, lateral meniscal tears, and medial and lateral meniscal tears, respectively. The AUCs of the horizontal, complex, radial, and longitudinal tears were 0.761, 0.850, 0.601, and 0.858, respectively. CONCLUSION: Our study showed that the CNN model has the potential to be used in diagnosing the presence of meniscal tears and differentiating the types of meniscal tears.
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Traumatismos do Joelho , Lesões do Menisco Tibial , Humanos , Traumatismos do Joelho/diagnóstico , Imageamento por Ressonância Magnética/métodos , Meniscos Tibiais/patologia , Redes Neurais de Computação , Estudos Retrospectivos , Ruptura/patologia , Lesões do Menisco Tibial/diagnóstico por imagem , Lesões do Menisco Tibial/patologiaRESUMO
BACKGROUND: Videofluoroscopic swallowing study (VFSS) is currently considered the gold standard to precisely diagnose and quantitatively investigate dysphagia. However, VFSS interpretation is complex and requires consideration of several factors. Therefore, considering the expected impact on dysphagia management, this study aimed to apply deep learning to detect the presence of penetration or aspiration in VFSS of patients with dysphagia automatically. METHODS: The VFSS data of 190 participants with dysphagia were collected. A total of 10 frame images from one swallowing process were selected (five high-peak images and five low-peak images) for the application of deep learning in a VFSS video of a patient with dysphagia. We applied a convolutional neural network (CNN) for deep learning using the Python programming language. For the classification of VFSS findings (normal swallowing, penetration, and aspiration), the classification was determined in both high-peak and low-peak images. Thereafter, the two classifications determined through high-peak and low-peak images were integrated into a final classification. RESULTS: The area under the curve (AUC) for the validation dataset of the VFSS image for the CNN model was 0.942 for normal findings, 0.878 for penetration, and 1.000 for aspiration. The macro average AUC was 0.940 and micro average AUC was 0.961. CONCLUSION: This study demonstrated that deep learning algorithms, particularly the CNN, could be applied for detecting the presence of penetration and aspiration in VFSS of patients with dysphagia.
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Aprendizado Profundo , Transtornos de Deglutição/diagnóstico , Deglutição/fisiologia , Fluoroscopia , Gravação em Vídeo , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Background and Objectives: This study investigated the usefulness of deep neural network (DNN) models based on 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) and blood inflammatory markers to assess the therapeutic response in pyogenic vertebral osteomyelitis (PVO). Materials and Methods: This was a retrospective study with prospectively collected data. Seventy-four patients diagnosed with PVO underwent clinical assessment for therapeutic responses based on clinical features during antibiotic therapy. The decisions of the clinical assessment were confirmed as 'Cured' or 'Non-cured'. FDG-PETs were conducted concomitantly regardless of the decision at each clinical assessment. We developed DNN models depending on the use of attributes, including C-reactive protein (CRP), erythrocyte sedimentation ratio (ESR), and maximum standardized FDG uptake values of PVO lesions (SUVmax), and we compared their performances to predict PVO remission. Results: The 126 decisions (80 'Cured' and 46 'Non-cured' patients) were randomly assigned with training and test sets (7:3). We trained DNN models using a training set and evaluated their performances for a test set. DNN model 1 had an accuracy of 76.3% and an area under the receiver operating characteristic curve (AUC) of 0.768 [95% confidence interval, 0.625-0.910] using CRP and ESR, and these values were 79% and 0.804 [0.674-0.933] for DNN model 2 using ESR and SUVmax, 86.8% and 0.851 [0.726-0.976] for DNN model 3 using CRP and SUVmax, and 89.5% and 0.902 [0.804-0.999] for DNN model 4 using ESR, CRP, and SUVmax, respectively. Conclusions: The DNN models using SUVmax showed better performances when predicting the remission of PVO compared to CRP and ESR. The best performance was obtained in the DNN model using all attributes, including CRP, ESR, and SUVmax, which may be helpful for predicting the accurate remission of PVO.
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Fluordesoxiglucose F18 , Osteomielite , Humanos , Estudos Retrospectivos , Tomografia por Emissão de Pósitrons/métodos , Osteomielite/diagnóstico por imagem , Osteomielite/tratamento farmacológico , Redes Neurais de Computação , Proteína C-ReativaRESUMO
This paper proposes a novel method for sports video scene classification with the particular intention of video summarization. Creating and publishing a shorter version of the video is more interesting than a full version due to instant entertainment. Generating shorter summaries of the videos is a tedious task that requires significant labor hours and unnecessary machine occupation. Due to the growing demand for video summarization in marketing, advertising agencies, awareness videos, documentaries, and other interest groups, researchers are continuously proposing automation frameworks and novel schemes. Since the scene classification is a fundamental component of video summarization and video analysis, the quality of scene classification is particularly important. This article focuses on various practical implementation gaps over the existing techniques and presents a method to achieve high-quality of scene classification. We consider cricket as a case study and classify five scene categories, i.e., batting, bowling, boundary, crowd and close-up. We employ our model using pre-trained AlexNet Convolutional Neural Network (CNN) for scene classification. The proposed method employs new, fully connected layers in an encoder fashion. We employ data augmentation to achieve a high accuracy of 99.26% over a smaller dataset. We conduct a performance comparison against baseline approaches to prove the superiority of the method as well as state-of-the-art models. We evaluate our performance results on cricket videos and compare various deep-learning models, i.e., Inception V3, Visual Geometry Group (VGGNet16, VGGNet19) , Residual Network (ResNet50), and AlexNet. Our experiments demonstrate that our method with AlexNet CNN produces better results than existing proposals.
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The Internet of Things (IoT) is a recent evolutionary technology that has been the primary focus of researchers for the last two decades. In the IoT, an enormous number of objects are connected together using diverse communications protocols. As a result of this massive object connectivity, a search for the exact service from an object is difficult, and hence the issue of scalability arises. In order to resolve this issue, the idea of integrating the social networking concept into the IoT, generally referred as the Social Internet of Things (SIoT) was introduced. The SIoT is gaining popularity and attracting the attention of the research community due to its flexible and spacious nature. In the SIoT, objects have the ability to find a desired service in a distributed manner by using their neighbors. Although the SIoT technique has been proven to be efficient, heterogeneous devices are growing so exponentially that problems can exist in the search for the right object or service from a huge number of devices. In order to better analyze the performance of services in an SIoT domain, there is a need to impose a certain set of rules on these objects. Our novel contribution in this study is to address the link selection problem in the SIoT by proposing an algorithm that follows the key properties of navigability in small-world networks, such as clustering coefficients, path lengths, and giant components. Our algorithm empowers object navigability in the SIoT by restricting the number of connections for objects, eliminating old links or having fewer connections. We performed an extensive series of experiments by using real network data sets from social networking sites like Brightkite and Facebook. The expected results demonstrate that our algorithm is efficient, especially in terms of reducing path length and increasing the average clustering coefficient. Finally, it reflects overall results in terms of achieving easier network navigation. Our algorithm can easily be applied to a single node or even an entire network.
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Presently, most deaths are caused by heart disease. To overcome this situation, heartbeat sound analysis is a convenient way to diagnose heart disease. Heartbeat sound classification is still a challenging problem in heart sound segmentation and feature extraction. Dataset-B applied in this study that contains three categories Normal, Murmur and Extra-systole heartbeat sound. In the purposed framework, we remove the noise from the heartbeat sound signal by applying the band filter, After that we fixed the size of the sampling rate of each sound signal. Then we applied down-sampling techniques to get more discriminant features and reduce the dimension of the frame rate. However, it does not affect the results and also decreases the computational power and time. Then we applied a purposed model Recurrent Neural Network (RNN) that is based on Long Short-Term Memory (LSTM), Dropout, Dense and Softmax layer. As a result, the purposed method is more competitive compared to other methods.
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Identification of the Internet of Things (IoT) devices has become an essential part of network management to secure the privacy of smart homes and offices. With its wide adoption in the current era, IoT has facilitated the modern age in many ways. However, such proliferation also has associated privacy and data security risks. In the case of smart homes and smart offices, unknown IoT devices increase vulnerabilities and chances of data theft. It is essential to identify the connected devices for secure communication. It is very difficult to maintain the list of rules when the number of connected devices increases and human involvement is necessary to check whether any intruder device has approached the network. Therefore, it is required to automate device identification using machine learning methods. In this article, we propose an accuracy boosting model (ABM) using machine learning models of random forest and extreme gradient boosting. Featuring engineering techniques are employed along with cross-validation to accurately identify IoT devices such as lights, smoke detectors, thermostat, motion sensors, baby monitors, socket, TV, security cameras, and watches. The proposed ensemble model utilizes random forest (RF) and extreme gradient boosting (XGB) as base learners with adaptive boosting. The proposed ensemble model is tested with extensive experiments involving the IoT Device Identification dataset from a public repository. Experimental results indicate a higher accuracy of 91%, precision of 93%, recall of 93%, and F1 score of 93%.
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The Food, Beverage & Tobacco (F&B) industry is an essential sector in the competitive economy. Procurement of production factors mainly depends on sales forecasting and the supply chain of raw materials. However, the conflict between Russia and Ukraine has jeopardized the global supply chain. As the conflict worsened, the world faced a food crisis, which was already a significant challenge due to the Covid-19 pandemic. Understanding how conflict-related disruptions in global food markets might affect the stock return of the F&B industry of South Korea, this study forecasts the stock returns on the KOSDAQ F&B sector. This paper highlights that the conflict resulted in immediate and far-reaching consequences on the global food supply chain and future crop harvesting in South Korea. As numerous algorithms have been widely used in predicting stock market returns, we use Autoregressive Integrated Moving Average (ARIMA) model for the prediction. Using daily returns from the KOSDAQ F&B industry from January 1999 to October 2022, the study proposes an ARIMA (2,2,3) model to forecast future movements of the stock returns. With an RMSE of 0.012, the prediction performance holds good using the ARIMA model. The results show a negative trend observed in the F&B sector returns for a few months, implying that sector stock returns decline as the conflict between Russia and Ukraine becomes more pronounced. This study also suggests that South Korea has massive scope to stabilize the demand for healthy, safe food, give more attention to domestic agribusiness, and make itself a self-sufficient agri-economy.
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Breast cancer is a common cause of female mortality in developing countries. Early detection and treatment are crucial for successful outcomes. Breast cancer develops from breast cells and is considered a leading cause of death in women. This disease is classified into two subtypes: invasive ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS). The advancements in artificial intelligence (AI) and machine learning (ML) techniques have made it possible to develop more accurate and reliable models for diagnosing and treating this disease. From the literature, it is evident that the incorporation of MRI and convolutional neural networks (CNNs) is helpful in breast cancer detection and prevention. In addition, the detection strategies have shown promise in identifying cancerous cells. The CNN Improvements for Breast Cancer Classification (CNNI-BCC) model helps doctors spot breast cancer using a trained deep learning neural network system to categorize breast cancer subtypes. However, they require significant computing power for imaging methods and preprocessing. Therefore, in this research, we proposed an efficient deep learning model that is capable of recognizing breast cancer in computerized mammograms of varying densities. Our research relied on three distinct modules for feature selection: the removal of low-variance features, univariate feature selection, and recursive feature elimination. The craniocaudally and medial-lateral views of mammograms are incorporated. We tested it with a large dataset of 3002 merged pictures gathered from 1501 individuals who had digital mammography performed between February 2007 and May 2015. In this paper, we applied six different categorization models for the diagnosis of breast cancer, including the random forest (RF), decision tree (DT), k-nearest neighbors (KNN), logistic regression (LR), support vector classifier (SVC), and linear support vector classifier (linear SVC). The simulation results prove that our proposed model is highly efficient, as it requires less computational power and is highly accurate.
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Deep learning is an advanced machine learning technique that is used in several medical fields to diagnose diseases and predict therapeutic outcomes. In this study, using anteroposterior ankle radiographs, we developed a convolutional neural network (CNN) model to diagnose osteochondral lesions of the talus (OLTs) using ankle radiographs as input data. We evaluated whether a CNN model trained on anteroposterior ankle radiographs could help diagnose the presence of OLT. We retrospectively collected 379 cases (OLT casesâ =â 133, non-OLT casesâ =â 246) of anteroposterior ankle radiographs taken at a university hospital between January 2010 and December 2020. The OLT was diagnosed using ankle magnetic resonance images of each patient. Among the 379 cases, 70% of the included data were randomly selected as the training set, 10% as the validation set, and the remaining 20% were assigned to the test set to evaluate the model performance. To accurately classify OLT and non-OLT, we cropped the area of the ankle on anteroposterior ankle radiographs, resized the image to 224â ×â 224, and used it as the input data. We then used the Visual Geometry Group Network model to determine whether the input image was OLT or non-OLT. The performance of the CNN model for the area under the curve, accuracy, positive predictive value, and negative predictive value on the test data were 0.774 (95% confidence interval [CI], 0.673-0.875), 81.58% (95% CI, 0.729-0.903), 80.95% (95% CI, 0.773-0.846), and 81.82% (95% CI, 0.804-0.832), respectively. A CNN model trained on anteroposterior ankle radiographs achieved meaningful accuracy in diagnosing OLT and demonstrated that it could help diagnose OLT.
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Tálus , Humanos , Tálus/diagnóstico por imagem , Tálus/patologia , Tornozelo , Estudos Retrospectivos , Radiografia , Redes Neurais de ComputaçãoRESUMO
Breast cancer is one of the most common invasive cancers in women and it continues to be a worldwide medical problem since the number of cases has significantly increased over the past decade. Breast cancer is the second leading cause of death from cancer in women. The early detection of breast cancer can save human life but the traditional approach for detecting breast cancer disease needs various laboratory tests involving medical experts. To reduce human error and speed up breast cancer detection, an automatic system is required that would perform the diagnosis accurately and timely. Despite the research efforts for automated systems for cancer detection, a wide gap exists between the desired and provided accuracy of current approaches. To overcome this issue, this research proposes an approach for breast cancer prediction by selecting the best fine needle aspiration features. To enhance the prediction accuracy, several feature selection techniques are applied to analyze their efficacy, such as principal component analysis, singular vector decomposition, and chi-square (Chi2). Extensive experiments are performed with different features and different set sizes of features to investigate the optimal feature set. Additionally, the influence of imbalanced and balanced data using the SMOTE approach is investigated. Six classifiers including random forest, support vector machine, gradient boosting machine, logistic regression, multilayer perceptron, and K-nearest neighbors (KNN) are tuned to achieve increased classification accuracy. Results indicate that KNN outperforms all other classifiers on the used dataset with 20 features using SVD and with the 15 most important features using a PCA with a 100% accuracy score.
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Deep learning is an advanced machine learning approach used in diverse areas such as image analysis, bioinformatics, and natural language processing. In the current study, using only one knee magnetic resonance image of each patient, we attempted to develop a convolutional neural network (CNN) to diagnose anterior cruciate ligament (ACL) tear. We retrospectively recruited 164 patients who had knee injury and underwent knee magnetic resonance imaging evaluation. Of 164 patients, 83 patients' ACLs were torn (20 patients, partial tear; 63 patients, complete tear), whereas 81 patients' ACLs were intact. We used a CNN algorithm. Of the included subjects, 79% were assigned randomly to the training set and the remaining 21% were assigned to the test set to measure the model performance. The area under the curve was 0.941 (95% CI, 0.862-1.000) for the classification of intact and tears of the ACL. We demonstrated that a CNN model trained using one knee magnetic resonance image of each patient could be helpful in diagnosing ACL tear.
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Lesões do Ligamento Cruzado Anterior , Lacerações , Humanos , Ligamento Cruzado Anterior/diagnóstico por imagem , Ligamento Cruzado Anterior/patologia , Estudos Retrospectivos , Artroscopia , Lesões do Ligamento Cruzado Anterior/diagnóstico por imagem , Lesões do Ligamento Cruzado Anterior/patologia , Ruptura/patologia , Imageamento por Ressonância Magnética/métodos , Lacerações/patologia , Redes Neurais de ComputaçãoRESUMO
COVID-19 pandemic is widely spreading over the entire world and has established significant community spread. Fostering a prediction system can help prepare the officials to respond properly and quickly. Medical imaging like X-ray and computed tomography (CT) can play an important role in the early prediction of COVID-19 patients that will help the timely treatment of the patients. The x-ray images from COVID-19 patients reveal the pneumonia infections that can be used to identify the patients of COVID-19. This study presents the use of Convolutional Neural Network (CNN) that extracts the features from chest x-ray images for the prediction. Three filters are applied to get the edges from the images that help to get the desired segmented target with the infected area of the x-ray. To cope with the smaller size of the training dataset, Keras' ImageDataGenerator class is used to generate ten thousand augmented images. Classification is performed with two, three, and four classes where the four-class problem has X-ray images from COVID-19, normal people, virus pneumonia, and bacterial pneumonia. Results demonstrate that the proposed CNN model can predict COVID-19 patients with high accuracy. It can help automate screening of the patients for COVID-19 with minimal contact, especially areas where the influx of patients can not be treated by the available medical staff. The performance comparison of the proposed approach with VGG16 and AlexNet shows that classification results for two and four classes are competitive and identical for three-class classification.
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COVID-19 vaccination raised serious concerns among the public and people are mind stuck by various rumors regarding the resulting illness, adverse reactions, and death. Such rumors are dangerous to the campaign against the COVID-19 and should be dealt with accordingly and timely. One prospective solution is to use machine learning-based models to predict the death risk for vaccinated people and clarify people's perceptions regarding death risk. This study focuses on the prediction of the death risks associated with vaccinated people followed by a second dose for two reasons; first to build consensus among people to get the vaccines; second, to reduce the fear regarding vaccines. Given that, this study utilizes the COVID-19 VAERS dataset that records adverse events after COVID-19 vaccination as 'recovered', 'not recovered', and 'survived'. To obtain better prediction results, a novel voting classifier extreme regression-voting classifier (ER-VC) is introduced. ER-VC ensembles extra tree classifier and logistic regression using soft voting criterion. To avoid model overfitting and get better results, two data balancing techniques synthetic minority oversampling (SMOTE) and adaptive synthetic sampling (ADASYN) have been applied. Moreover, three feature extraction techniques term frequency-inverse document frequency (TF-IDF), bag of words (BoW), and global vectors (GloVe) have been used for comparison. Both machine learning and deep learning models are deployed for experiments. Results obtained from extensive experiments reveal that the proposed model in combination with TF-TDF has shown robust results with a 0.85 accuracy when trained on the SMOTE-balanced dataset. In line with this, validation of the proposed voting classifier on binary classification shows state-of-the-art results with a 0.98 accuracy. Results show that machine learning models can predict the death risk with high accuracy and can assist the authors in taking timely measures.
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Vacinas contra COVID-19/efeitos adversos , COVID-19 , Sistemas de Notificação de Reações Adversas a Medicamentos , COVID-19/prevenção & controle , Humanos , Política , Estudos ProspectivosRESUMO
Vaccination for the COVID-19 pandemic has raised serious concerns among the public and various rumours are spread regarding the resulting illness, adverse reactions, and death. Such rumours can damage the campaign against the COVID-19 and should be dealt with accordingly. One prospective solution is to use machine learning-based models to predict the death risk for vaccinated people by utilizing the available data. This study focuses on the prognosis of three significant events including 'not survived', 'recovered', and 'not recovered' based on the adverse events followed by the second dose of the COVID-19 vaccine. Extensive experiments are performed to analyse the efficacy of the proposed Extreme Regression- Voting Classifier model in comparison with machine learning models with Term Frequency-Inverse Document Frequency, Bag of Words, and Global Vectors, and deep learning models like Convolutional Neural Network, Long Short Term Memory, and Bidirectional Long Short Term Memory. Experiments are carried out on the original, as well as, a balanced dataset using Synthetic Minority Oversampling Approach. Results reveal that the proposed voting classifier in combination with TF-IDF outperforms with a 0.85 accuracy score on the SMOTE-balanced dataset. In line with this, the validation of the proposed voting classifier on binary classification shows state-of-the-art results with a 0.98 accuracy.
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Educational Data Mining is widely used for predicting student's performance. It's a challenging task because a plethora of features related to demographics, personality traits, socio-economic, and environmental may affect students' performance. Such varying features may depend on the level of study, program offered, nature of subject, and geographical location. This study attempted to predict the final semester's results of students studying Doctor of Veterinary Medicine (DVM) based on their pre-admission academic achievements, demographics, and first semester performance. The imbalanced data led to non-generic prediction models, so it was addressed through synthetic minority oversampling technique. Among five prediction models, the Support Vector Machine led the best with 92% accuracy. The decision tree model identified key features affecting students' performance. The analysis led to the conclusion that marks obtained in Biology, Islamiat, and Urdu at Matric and English at Intermediate level affected the students' performance in their final semester. The findings provide useful information to predict students' performance and guidelines for academic institutes' management regarding improving students' achievement. It is speculated that adoption of digital transformation may help reduce difficulty faced in data collection and analysis.
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Sucesso Acadêmico , Estudantes , Demografia , Escolaridade , HumanosRESUMO
The molecular weight and isoelectric point of the proteins are very important parameters that control their subcellular localization and subsequent function. Although the genome sequence data of the plant kingdom improved enormously, the proteomic details have been poorly elaborated. Therefore, we have calculated the molecular weight and isoelectric point of the plant proteins and reported them in this database. A database, PlantMWpIDB, containing protein data from 342 plant proteomes was created to provide information on plant proteomes for hypothesis formulation in basic research and for biotechnological applications. The Molecular weight and isoelectric point (pI) are important molecular parameters of proteins that are useful when conducting protein studies involving 2D gel electrophoresis, liquid chromatography-mass spectrometry, and X-ray protein crystallography. PlantMWpIDB provides an easy-to-use and efficient interface for search options and generates a summary of basic protein parameters. The database represents a virtual 2D proteome map of plants, and the molecular weight and pI of a protein can be obtained by searching on the name of a protein, a keyword, or by a list of accession numbers. The PlantMWpIDB database also allows one to query protein sequences. The database can be found in the following link https://plantmwpidb.com/ . The individual 2D virtual proteome map of the plant kingdom will enable us to understand the proteome diversity between different species. Further, the molecular weight and isoelectric point of individual proteins can enable us to understand their functional significance in different species.
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Proteoma , Proteômica , Bases de Dados de Proteínas , Eletroforese em Gel Bidimensional , Focalização Isoelétrica , Ponto Isoelétrico , Peso Molecular , Plantas/metabolismo , Proteoma/metabolismo , Proteômica/métodosRESUMO
The Internet Movie Database (IMDb), being one of the popular online databases for movies and personalities, provides a wide range of movie reviews from millions of users. This provides a diverse and large dataset to analyze users' sentiments about various personalities and movies. Despite being helpful to provide the critique of movies, the reviews on IMDb cannot be read as a whole and requires automated tools to provide insights on the sentiments in such reviews. This study provides the implementation of various machine learning models to measure the polarity of the sentiments presented in user reviews on the IMDb website. For this purpose, the reviews are first preprocessed to remove redundant information and noise, and then various classification models like support vector machines (SVM), Naïve Bayes classifier, random forest, and gradient boosting classifiers are used to predict the sentiment of these reviews. The objective is to find the optimal process and approach to attain the highest accuracy with the best generalization. Various feature engineering approaches such as term frequency-inverse document frequency (TF-IDF), bag of words, global vectors for word representations, and Word2Vec are applied along with the hyperparameter tuning of the classification models to enhance the classification accuracy. Experimental results indicate that the SVM obtains the highest accuracy when used with TF-IDF features and achieves an accuracy of 89.55%. The sentiment classification accuracy of the models is affected due to the contradictions in the user sentiments in the reviews and assigned labels. For tackling this issue, TextBlob is used to assign a sentiment to the dataset containing reviews before it can be used for training. Experimental results on TextBlob assigned sentiments indicate that an accuracy of 92% can be obtained using the proposed model.
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Deep learning (DL) is an advanced machine learning approach used in diverse areas such as bioinformatics, image analysis, and natural language processing. Here, using brain magnetic resonance imaging (MRI) data obtained at early stages of infarcts, we attempted to develop a convolutional neural network (CNN) to predict the ambulatory outcome of corona radiata infarction at six months after onset. We retrospectively recruited 221 patients with corona radiata infarcts. A favorable outcome of ambulatory function was defined as a functional ambulation category (FAC) score of ≥ 4 (able to walk without a guardian's assistance), and a poor outcome of ambulatory function was defined as an FAC score of < 4. We used a CNN algorithm. Of the included subjects, 69.7% (n = 154) were assigned randomly to the training set and the remaining 30.3% (n = 67) were assigned to the validation set to measure the model performance. The area under the curve was 0.751 (95% CI 0.649-0.852) for the prediction of ambulatory function with the validation dataset using the CNN model. We demonstrated that a CNN model trained using brain MRIs captured at an early stage after corona radiata infarction could be helpful in predicting long-term ambulatory outcomes.