Detalhe da pesquisa
1.
Identification of (-)-Epigallocateshin gallate derivatives promoting innate immune activation via 2',3'-cyclic GMP-AMP-stimulator of interferon genes pathway.
Bioorg Med Chem Lett
; 90: 129325, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37182610
2.
Synthesis and biological evaluation of indane-based fluorescent probes for detection of amyloid-ß aggregates in Alzheimer's disease.
Bioorg Med Chem
; 95: 117513, 2023 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37931520
3.
Identification of novel pyrrolopyrimidine and pyrrolopyridine derivatives as potent ENPP1 inhibitors.
J Enzyme Inhib Med Chem
; 37(1): 2434-2451, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36069240
4.
Serotonin Receptors as Therapeutic Targets for Autism Spectrum Disorder Treatment.
Int J Mol Sci
; 23(12)2022 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35742963
5.
Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model.
J Enzyme Inhib Med Chem
; 36(1): 856-868, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33771089
6.
Modulation of Serotonin Receptors in Neurodevelopmental Disorders: Focus on 5-HT7 Receptor.
Molecules
; 26(11)2021 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34199418
7.
Development of carbapenem-based fluorogenic probes for the clinical screening of carbapenemase-producing bacteria.
Bioorg Chem
; 94: 103405, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31806156
8.
Synthesis and Biological Evaluation of Disubstituted Pyrimidines as Selective 5-HT2C Agonists.
Molecules
; 24(18)2019 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31491978
9.
Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's disease.
Acta Neuropathol
; 134(5): 729-748, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28593442
10.
Neuropathic pain-alleviating effects of pyrazole-conjugated arylsulfonamides as 5-HT6 receptor antagonists.
Bioorg Med Chem Lett
; 27(17): 4146-4149, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28729057
11.
Quercetin-glutamic acid conjugate with a non-hydrolysable linker; a novel scaffold for multidrug resistance reversal agents through inhibition of P-glycoprotein.
Bioorg Med Chem
; 25(3): 1219-1226, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28043777
12.
Identification of Optically Active Pyrimidine Derivatives as Selective 5-HT2C Modulators.
Molecules
; 22(9)2017 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28846591
13.
Novel JAK1-selective benzimidazole inhibitors with enhanced membrane permeability.
Bioorg Med Chem Lett
; 26(14): 3213-3215, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27261178
14.
Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists.
Bioorg Med Chem Lett
; 26(1): 140-4, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26598462
15.
Dicyanovinyl-substituted J147 analogue inhibits oligomerization and fibrillation of ß-amyloid peptides and protects neuronal cells from ß-amyloid-induced cytotoxicity.
Org Biomol Chem
; 13(37): 9564-9, 2015 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26303522
16.
A curcumin-based molecular probe for near-infrared fluorescence imaging of tau fibrils in Alzheimer's disease.
Org Biomol Chem
; 13(46): 11194-9, 2015 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26488450
17.
Synthesis of novel dihydropyridothienopyrimidin-4,9-dione derivatives.
Molecules
; 20(3): 5074-84, 2015 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25808151
18.
Facile diverted synthesis of pyrrolidinyl triazoles using organotrifluoroborate: discovery of potential mPTP blockers.
Org Biomol Chem
; 12(47): 9674-82, 2014 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25348904
19.
Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression.
Bioorg Med Chem
; 22(17): 4587-96, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25127461
20.
Synthesis and in vitro evaluation of the antitubercular and antibacterial activity of novel oxazolidinones bearing octahydrocyclopenta[c]pyrrol-2-yl moieties.
Chem Pharm Bull (Tokyo)
; 62(12): 1214-24, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25297523