Detalhe da pesquisa
1.
Architecture of the outbred brown fat proteome defines regulators of metabolic physiology.
Cell
; 185(24): 4654-4673.e28, 2022 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36334589
2.
A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging.
Cell
; 180(5): 968-983.e24, 2020 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32109415
3.
pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise.
Cell
; 183(1): 62-75.e17, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32946811
4.
Author Correction: Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses.
Nat Immunol
; 20(11): 1555, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31551573
5.
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses.
Nat Immunol
; 20(9): 1186-1195, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31384058
6.
A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.
Cell
; 163(3): 643-55, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26496606
7.
Lactate regulates cell cycle by remodelling the anaphase promoting complex.
Nature
; 616(7958): 790-797, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36921622
8.
Mitochondrial uncouplers induce proton leak by activating AAC and UCP1.
Nature
; 606(7912): 180-187, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35614225
9.
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.
Nature
; 599(7884): 296-301, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34707293
10.
Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine.
Nature
; 593(7860): 580-585, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33981039
11.
Exercise preserves physical fitness during aging through AMPK and mitochondrial dynamics.
Proc Natl Acad Sci U S A
; 120(2): e2204750120, 2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36595699
12.
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor.
Nat Chem Biol
; 19(7): 815-824, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36823351
13.
H+ transport is an integral function of the mitochondrial ADP/ATP carrier.
Nature
; 571(7766): 515-520, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31341297
14.
Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel.
Nat Chem Biol
; 18(5): 461-469, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484255
15.
Accumulation of succinate controls activation of adipose tissue thermogenesis.
Nature
; 560(7716): 102-106, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30022159
16.
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Nature
; 556(7699): 113-117, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29590092
17.
Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry.
J Am Chem Soc
; 145(40): 21937-21944, 2023 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37767920
18.
Sample multiplexing for targeted pathway proteomics in aging mice.
Proc Natl Acad Sci U S A
; 117(18): 9723-9732, 2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32332170
19.
Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity.
Proc Natl Acad Sci U S A
; 117(20): 10789-10796, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32358195
20.
Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes.
J Biol Chem
; 296: 100137, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268383